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Chemical contaminants in human milk

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Residue Reviews

Part of the book series: Residue Reviews ((RECT,volume 89))

Abstract

It has been known since the last century that maternal milk sometimes may contain chemical contaminants which could have adverse effects on nursing infants. Such experiences came mainly from cases of exposure to occupational chemicals or drugs. Since 1950, it has further been known that human milk may contain potentially hazardous persistent environmental chemicals in concentrations higher than in cow’s milk.

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References

  • Abbott, D. C., G. B. Collins, R. Goulding, and R. A. Hoodless: Organochlorine pesticide residues in human fat in the United Kingdom 1976–7. Brit. Med. J. 283, 1425 (1981).

    CAS  Google Scholar 

  • Acker, L.: Zur Kontamination der Frauenmilch mit chlor organischen Verbindungen. Geburtsh. u. Frauenheilk. 41, 882 (1981).

    CAS  Google Scholar 

  • Acker, L., and E. Schulte: Über das Vorkommen von chlorierten Biphenylen und Hexachlorbenzol neben chlorierten Insektiziden in Humanmilch und menschlichem Fettgewebe. Naturwis. 57, 497 (1970).

    CAS  Google Scholar 

  • Acker, L., and E. Schulte: Zum Vorkommen von Hexachlorbenzol und polychlorierten Biphenylen neben chlorierten Insektiziden in menschlichem Fettgewebe und im Humanmilch. Ernährungsforschung 16, 559 (1971).

    Google Scholar 

  • Ackerman, L. B.: Humans: Overview of human exposure to dieldrin residues in the environment and current trends of residue levels in tissue. Pest. Monit. J. 14, 64 (1980).

    CAS  Google Scholar 

  • Adamovic, V., B. Sokić, and O. Petrović: Zur Kenntnis der Faktoren, welche auf das Organochlorinsektizide im Organismus der neugeboren Einwirken. Ernährungsforschung 16, 579 (1971).

    Google Scholar 

  • Adamovic, V. M.: Rückstände in der Muttermilch. In: Bewertung von Risiken für die Gesundheit. Symp. Berlin Maj 1976, pp. 94–96. Stuttgart: G. Fischer Verlag (1977).

    Google Scholar 

  • Adamovic, V. M., B. Sokić, and Milena-Jovanovic-Smiljanska: Some observations concerning the ratio of the intake of organo chlorine insecticides through food and amount excreted in the milk of breast-feeding mothers. Bull. Envi-ronm. Contam. Toxicol. 20, 280 (1978).

    CAS  Google Scholar 

  • Albert, L.: Residuos de plaguicidas organoclorados en leche materna y riesgo para la salud. Bol. Of. Sanit. Panam. 91, 15 (1981).

    CAS  Google Scholar 

  • Allen, J. R., D. A. Barsotti, and L. A. Carstens: Residual effects of polychlori-nated biphenyls on adult nonhuman primates and their offspring. J. Toxicol. Environ. Health 6, 55 (1980).

    PubMed  CAS  Google Scholar 

  • Amin-Zaki, L., S. ElHassani, M. A. Majeed, T. W. Clarkson, R. A. Doherty, M. R. Greenwood, and T. Giovanoli-Jakubczak: Perinatal methylmercury poisoning in Iraq. Amer. J. Dis. Child. 130, 1070 (1976).

    PubMed  CAS  Google Scholar 

  • Amin-Zaki, L., S. ElHassani, M. A. Majeed, T. W. Clarkson, R. A. Doherty, M. R. Greenwood, and T. Giovanoli-Jakubczak: Methylmercury poisoning in mothers and their suckling infants. In B. Holmstedt et al. (eds.), Mechanisms of toxicity and hazard evaluation, pp. 75–78. Elsevier/North-Holland Biomedical Press (1980).

    Google Scholar 

  • Andersen, A. N., C. Lund-An der sen, E. Henriksen, and J. Vogelius: Cigaretrygn-ings indflydelse på graviditet, fødsel, amnings-og amenoréperiode. Ugeskr. Læger 28, 2115 (1982).

    Google Scholar 

  • Anonymous: Tabel over koncentrationer af DDT + DDE of af PCB i moder-mælksprøver fra Odense Sygehus. Odense Kommunes Laboratorium (1973).

    Google Scholar 

  • Anonymous: Beretning om undersøgelser af levnedsmidler og vand m. m. for året 1973, p. 30. Stadsdyrlægen i Odense (1974).

    Google Scholar 

  • Anonymous: Materiale til årsberetning for 1974. Stadsdyrlægen i Odense (1975 a).

    Google Scholar 

  • Anonymous: Findings of survey on PCB pollution of mother’s milk bared. Japan Environmental Summary 3, 3 (1975 b).

    Google Scholar 

  • Anonymous: Report on cacinogenesis bioassay of chlordane and heptachlor. Amer. Ind. Hyg. Assoc. J. 38, A–32 (1977).

    Google Scholar 

  • Anonymous: WHO/UNICEF meeting. Encouragement and support of breast-feeding. Lancet II(8147), 841 (1979).

    Google Scholar 

  • Anonymous: Report of the Government Chemist 1981. Organochlorine residues in human milk. Her Majesty’s Stationary Office London, Chapt. 1.5 (1982).

    Google Scholar 

  • Arnon, S. S., K. Damus, B. Thompson, T. F. Midura, and J. Chin: Protective role of human milk against sudden death from infant botulism. J. Pediatr. 100 568 (1982).

    PubMed  CAS  Google Scholar 

  • Ari, L.: Levels of chlorinated remnants in native, pasteurized and lyophilized breast milk. (In Hungarian) Egészségtudomány 22, 38 (1977).

    Google Scholar 

  • Bagnell, P. C., and H. A. Ellenberger: Obstructive jaundice due to a chlorinated hydrocarbon in breast milk. Can. Med. Assoc. J. 117, 1047 (1977).

    PubMed  CAS  Google Scholar 

  • Bailey, J., V. Knauf, W. Mueller, and W. Hobson: Transfer of hexachlorobenzene and poly chlorinated biphenyls to nursing infant Rhesus monkeys: Enhanced toxicity. Environ. Res. 21, 190 (1980).

    PubMed  CAS  Google Scholar 

  • Bakir, F., S. F. Damluji, L. Amin-Zaki, M. Murtadha, A. Khalidi, N. Y. Ak-Rawi, S. Tikriti, H. I. Dhamir, T. W. Clarkson, J. C. Smith, and R. A. Doherty: Methylmercury poisoning in Iraq. Science 181, 230 (1973).

    PubMed  CAS  Google Scholar 

  • Bakken, A. F., and M. Seip: Insecticides in human breast milk. Acta Pædiatr. Scand. 65, 535 (1976).

    PubMed  CAS  Google Scholar 

  • Baluja, G., L. M. Hernandez, Ma. J. Gonzales, and Ma. C. Rico: Presence of organochlorine pesticides, polychlorinated biphenyls and mercury in Spanish human milk samples. Bull. Environm. Contam.Toxicol. 28, 573 (1982).

    CAS  Google Scholar 

  • Barnett, R., A. J. D’Ercole, J. D. Cain, and R. D. Arthur: Organochlorine pesticide residues in human milk samples from women living in Northwest and Northeast, Mississippi, 1973–75. Pest. Monit. J. 13, 47 (1979).

    CAS  Google Scholar 

  • Bauza, C. A.: Residuos de plaguicidas organoclorados en leche de madres de Montevideo. Arch. Pediatr. Uruguay 46, 31 (1975); through Pest. Abstr. 75-2325 (1975).

    Google Scholar 

  • Bell, R. R., and J. T. Spickett: The influence of milk in the diet on the toxicity of orally ingested lead in rats. Food Cosmet. Toxicol. 19, 429 (1981).

    PubMed  CAS  Google Scholar 

  • Bhattacharyya, M. H., B. D. Whelton, and D. P. Peterson: Gastrointestinal absorption of cadmium in mice during gestation and lactation 1. Short-term exposure studies. Toxicol. Applied Pharmacol. 61, 335 (1981).

    CAS  Google Scholar 

  • Bjerk, J. E.: Rester av DDT og polyklorerte bifenyler i Norsk humant materiale. T. Norske Lægeforen. 92, 15 (1972).

    PubMed  CAS  Google Scholar 

  • Bradt, P. T., and R. C. Herrenkohl: DDT in human milk. What determines the levels? Sci. Total Environ. 6, 161 (1976).

    CAS  Google Scholar 

  • Branski, D.: The prevalence of disease in the first year of life: Human and cow milk compared. In S. Freier and A. I. Eidelman (eds.): Human milk. Its biological and social value, p. 209. Amsterdam-Oxford-Princeton: Excerpta Medica (1980).

    Google Scholar 

  • Brauw, M. C. T. N. de, C. van Ingen, and J. H. Koeman: Mirex in seals. Sci. Total Environ. 2, 196 (1973).

    Google Scholar 

  • Brevik, E. M.: Gas Chromatographic method for the determination of organo-chlorine pesticides in human milk. Bull. Environm. Contamin. Toxicol. 19, 281 (1978).

    CAS  Google Scholar 

  • Brevik, E. M., and J. E. Bjerk: Organochlorine compounds in Norwegian human fat and milk. Acta Pharmacol. et Toxicol. 43, 59 (1978).

    CAS  Google Scholar 

  • Brilliant, L., G. V. Amburg, J. Isbister, H. Humphrey, K. Wilcox, J. Eyster, A. W. Bloomer, and H. Price: Breast-milk monitoring to measure Michigan’s contamination with polybrominated biphenyls. Lancet II, 643 (1978).

    Google Scholar 

  • Bronisz, H., and J. Ochynski: DDT and DDE in human milk. (In Polish) Biul. Inst. Ochr. Rosl. 41, 99 (1968).

    Google Scholar 

  • Cai, A. X., and Y. S. Bao: Placental transfer, secretion into mother’s milk of carbon disulphide and the effects on maternal function of viscose rayon workers. Ind. Health 19, 15 (1981).

    PubMed  CAS  Google Scholar 

  • Campos, M. de, and A. F. Olszyna-Marzys: Contamination of human milk with chlorinated pesticides in Guatemala and in El Salvador. Arch. Environm. Contam. Toxicol. 8, 43 (1979).

    Google Scholar 

  • Carter, L. H.: Michigan’s PBB incident: Chemical mix-up leads to disaster. Science 192, 240 (1976).

    PubMed  CAS  Google Scholar 

  • Casey, C. E.: The content of some trace elements in infant milk foods and supplements available in New Zealand. N. Z. Med. J. 85, 275 (1977).

    PubMed  CAS  Google Scholar 

  • Cerutti, G., A. Gerosa, and R. Zappavigna: Residui di antiparassitari organici clorurati in latti di donna. Latte, 1, 317 (1976).

    CAS  Google Scholar 

  • Chen, E.: PBB: An American tragedy. Englewood Cliffs, N.J.: Prentice-Hall (1979).

    Google Scholar 

  • Clement, J. G., and A. B. Okey: Reproduction in female rats born to DDT-treated parents. Bull. Environm. Contam. Toxicol. 12, 373 (1974).

    CAS  Google Scholar 

  • Cordle, F., P. Corneliussen, C. Jelinek, G. Hackley, R. Lehmann, J. McLaughlin, R. Rhoden, and R. Shapiro: Human exposure to polychlorinated biphenyls and polybrominated biphenyls. Environ. Health Persp. 24, 157 (1978).

    CAS  Google Scholar 

  • Coté, C. J., N. B. Kenepp, S. B. Reed, and G. E. Strobel: Trace concentrations of halothane in human breast milk. Br. J. Anaesth. 48, 541 (1976).

    PubMed  Google Scholar 

  • Courtney, K. D.: Hexachlorobenzene (HCB): A review. Environ. Res. 20, 225 (1979).

    PubMed  CAS  Google Scholar 

  • Cripps, D. J., A. Gocmen, and H. A. Peters: Porphyria Turcica. Twenty years after hexachlorobenzene intoxication. Arch. Dermatol. 116, 46 (1980).

    PubMed  CAS  Google Scholar 

  • Cruz, J. R., B. Garcia, J. J. Urrutia, B. Carlsson, and L. Å. Hanson: Food antibodies in milk from Guatemalan women. J. Pediatr. 99, 600 (1981).

    PubMed  CAS  Google Scholar 

  • Curley, A., and R. Kimbrough: Chlorinated hydrocarbon insecticides in plasma and milk of pregnant and lactating women. Arch. Environ. Health. 18, 156 (1969).

    PubMed  CAS  Google Scholar 

  • Currie, R. A., V. W. Kadis, W. E. Breitkreitz, G. B. Cunningham, and G. W. Bruns: Pesticide residues in human milk, Alberta, Canada.-1966–70, 1977–78. Pest. Monit. J. 13, 52 (1979).

    CAS  Google Scholar 

  • Damaskin, V. I.: The extent of the accumulation of DDT in the human body in connection with its assimulation with food and its toxic effect. (In Russian) Gig. Sanit. 30, 109 (1965).

    PubMed  CAS  Google Scholar 

  • Davies, J. E., W. F. Edmundson, A. Raffonelli, J. C. Cassady, and C. Morgade: The role of social class in human pesticide pollution. Amer. J. Epidem. 96, 334 (1972).

    CAS  Google Scholar 

  • De Bellini, Y., J. Cressely, A. Deluzarche, and A. Hazemann: Pesticides Organochlores dans le lait de femme. Ann. Fals. Exp. Chim. 70, 567 (1977).

    Google Scholar 

  • Deutsche Forschungsgemeinschaft (DFG): Rückstände in Frauenmilch-Situation und Bewertung. Bonn: Harald Boldt Verlag (1978).

    Google Scholar 

  • Dillon, H. K., D. J. Wilson, and W. Schaffner: Lead concentrations in human milk. Amer. J. Dis. Child. 128, 491 (1974).

    PubMed  CAS  Google Scholar 

  • Dillon, J.-C., G. B. Martin, and H. T. O’Brien: Pesticide residues in human milk. Food Cosmet. Toxicol. 19, 437 (1981).

    PubMed  CAS  Google Scholar 

  • Doguchi, M.: Polychlorinated terphenyls as an environmental pollutant in Japan. Ecotox. Environ. Safety 1, 239 (1977).

    CAS  Google Scholar 

  • Doucette, J. S.: Is breast-feeding still safe for babies? Amer. J. Maternal Child Nursing, p. 345 (1978).

    Google Scholar 

  • Dyment, P. G., L. M. Hebertson, W. J. Decker, E. D. Gomes, and J. S. Wiseman: Relationship between levels of chlorinated hydrocarbon insecticides in human milk and serum. Bull. Environm. Contam. Toxicol. 6, 449 (1971 a).

    CAS  Google Scholar 

  • Dyment, P. G., L. M. Hebertson, E. D. Gomes, J. S. Wiseman, and R. W. Hornabrook: Absence of polychlorinated biphenyls in human milk and serum from Texas and human milk from New Guinea. Bull. Environm. Contam. Toxicol. 6, 532 (1971b).

    Google Scholar 

  • Eckenhausen, F. W., D. Bennett, K. I. Beynon, and K. E. Elgar: Organochlorine pesticide concentration in perinatal samples from mothers and babies. Arch. Environ. Health 36, 81 (1981).

    PubMed  CAS  Google Scholar 

  • Egan, H., R. Goulding, J. Roburn, and J. O’G. Tatton: Organo-chlorine pesticide residues in human fat and human milk. Brit. Med. J. 2, 66 (1965).

    PubMed  CAS  Google Scholar 

  • Engst, R., and R. Knoll: DDT-und DDE-Rückstände in human Milch. Ernährungsforschung 16, 569 (1971).

    Google Scholar 

  • Engst, R., and R. Knoll: Rückstände von chlorierten Kohlenwasserstoffen in Humanmilch. Pharmazie 27, 526 (1972).

    PubMed  CAS  Google Scholar 

  • EPA: Manual of analytical methods for the analysis of pesticides in human and environmental samples. U.S. Environmental Protection Agency. EPA-600/ 8-80-038 (1980).

    Google Scholar 

  • Evans, G. W., and P. E. Johnson: Characterization and quantitation of a zinc-binding ligand in human milk. Pediatr. Res. 14, 876 (1980).

    PubMed  CAS  Google Scholar 

  • Fahim, M. S., R. Bennett and D. G. Hall: Effect of DDT on the nursing neonate. Nature 228, 1222 (1970).

    PubMed  CAS  Google Scholar 

  • FAO/WHO: Pesticide residues in food. Rome (1970).

    Google Scholar 

  • FAO/WHO: Evaluation of certain food additives and the contaminants mercury, lead and cadmium. Tech. Rept. Ser. No. 505, Geneva (1972).

    Google Scholar 

  • FAO/WHO: Pesticide residues in food. Geneva (1974).

    Google Scholar 

  • FAO/WHO: Joint FAO/WHO food and animal feed contamination monitoring programme. Summary of data received from collaborating centres — 1977 to 1980. Part B-Contaminants. Geneva, World Health Organization (1981).

    Google Scholar 

  • Fernandez, J. C. G.: Estudion y comentarios sobre impregnacion humana por plagnicidas organoclorados en la republica Argentina. Medicine 34, 393 (1974).

    Google Scholar 

  • Fischbein, L.: Chromatographic and biological aspects of DDT and its metabolites. J. Chromatogr. 98, 177 (1974).

    Google Scholar 

  • Finberg, L.: PBBs: The ladies milk is not burning. J. Pediatr. 90, 511 (1977).

    PubMed  CAS  Google Scholar 

  • Fomon, S. J.: Infant nutrition, 2nd ed. Philadelphia: Saunders (1974).

    Google Scholar 

  • Fransson, G.-B., and B. Lönnerdal: Iron in human milk. J. Pediatr. 96, 380 (1980).

    CAS  Google Scholar 

  • Fries, G. F., and G. S. Marrow: Excretion of polybrominated biphenyls into the milk of cows. J. Dairy Sci. 58, 947 (1975).

    PubMed  CAS  Google Scholar 

  • Fujita, M., and E. Takabatake: Mercury levels in human maternal and neonatal blood, hair and milk. Bull. Environm. Contam. Toxicol. 18, 205 (1977).

    CAS  Google Scholar 

  • Gaines, T. B., and R. D. Kimbrough: Oral toxicity of mirex in adult and suckling rats. Arch. Environ. Health 21, 7 (1970).

    PubMed  CAS  Google Scholar 

  • Galster, A.: Mercury in Alaskan Eskimo mothers and infants. Environ. Health Persp. 15, 135 (1976).

    CAS  Google Scholar 

  • Garcia, J. D., M. G. Yang, P. S. Belo, and J. H. C. Wang: Carbon-mercury bond breakage in milk, cerebrum, liver and kidney of rats fed methyl mercuric chloride. Proc. Soc. Exp. Biol. Med. 146, 190 (1974).

    PubMed  CAS  Google Scholar 

  • Gatti, G. L.: Pesticide residues in human fat and human milk in the nine Member States of the European Community, Luxembourg, CEC (1974).

    Google Scholar 

  • Gerrard, J. W.: Breast-feeding: Second thoughts. Pediatrics 54, 757 (1974).

    PubMed  CAS  Google Scholar 

  • Getty, S. M., D. E. Rickert, and A. L. Trapp: Polybrominated biphenyl (PBB) toxicosis: An environmental accident. CRC Crit. Rev. Environ. Control 7, 309 (1977).

    CAS  Google Scholar 

  • Gyimothi, J.: Über die Rückstandsbelastung von Frauenmilch an Organochlor-pesticiden in Abhängigheit zur laktations Zeit. Forschungsberichte 4/79, p. 317. Bundesministerium für Gesundheit und Umweltschutz, Wien (1979).

    Google Scholar 

  • Gochfeld, M.: Pesticides and the nursing mother. Pediatrics 50, 169 (1972).

    PubMed  CAS  Google Scholar 

  • Goursaud, J., F. M. Luquet, and J. Casalis: Sur la pollution des laits de femme par les résidus de pesticides dans les départements du Nord et du PasdeCalais. Lait 508, 559 (1971).

    Google Scholar 

  • Graca, I., A. M. S. S. Fernandes, and H. C. Mourao: Organochlorine insecticide residues in human milk in Portugal. Pest. Monit. J. 8, 148 (1974).

    CAS  Google Scholar 

  • Gracheva, G. V.: The possibility of DDT accumulation in the organism of persons not having occupational contact with it. (In Russian) Faktory Vneshn. Sredy ikh Znachen. 1, 125 (1969).

    Google Scholar 

  • Gracheva, G. V.: DDT execretion with the milk of nursing mothers occupationally unexposed to the effect of this insecticide. (In Russian) Vop. Pitan. 29, 75 (1970).

    PubMed  CAS  Google Scholar 

  • Grant, D. L., J. Mes, and R. Frank: PCB residues in human adipose tissue and milk. National Conference on Polychlorinated Biphenyls. Chicago, Nov. 1975, p. 144. U.S. Environmental Protection Agency Conf. Proc: (EPA-560/6-75-004) (1976).

    Google Scholar 

  • Grebbenikov, and Soroka: Micro-element content in breast milk. (In Russian) Pediatrija 6, 16 (1963).

    Google Scholar 

  • Greenwood, M. R., T. W. Clarkson, R. A. Doherty, A. H. Gates, L. Amin-Zaki, S. ElHassani, and M. A. Majeed: Blood clearance half-times in lactating and nonlactating members of a population exposed to methylmercury. Environ. Res. 16, 48 (1978).

    PubMed  CAS  Google Scholar 

  • Gulko, A. G., N. I. Zimnitsa, A. P. Diskalenko, V. F. Chernokan, and V. F. Bubucha: Pesticide carriers among certain population groups of Moldavia. (In Russian) Gig. Sanit. 4, 36 (1978).

    Google Scholar 

  • Gutenmann, W. H., and D. J. Lisk: Tissue storage and excretion in milk of polybrominated biphenyls in ruminants. J. Agr. Food Chem. 23, 463 (1975).

    Google Scholar 

  • Hadjimarkos, D. M., and T. R. Shearer: Selenium in mature human milk. Amer. J. Gin. Nutr. 26, 583 (1973).

    CAS  Google Scholar 

  • Hagyard, S. B., W. H. Brown, J. W. Stull, F. M. Whiting, and S. R. Kemberling: DDT and DDE content of human milk in Arizona. Bull. Environm. Con-tarn. Toxicol. 9, 169 (1973).

    CAS  Google Scholar 

  • Hall, B.: Uniformity of human milk. Amer. J. Clin. Nutr. 32, 304 (1979).

    PubMed  CAS  Google Scholar 

  • Hambraeus, L.: Proprietary milk versus human breast milk in infant feeding. A critical appraisal from the nutritional point of view. Pediatric. Clin. N. America 24, 17 (1977).

    CAS  Google Scholar 

  • Hambraeus, L., B. Lönnerdal, E. Forsum, and M. Gebre-Medhin: Nitrogen and protein compounds of human milk. Acta Paediatr. Scand. 67, 561 (1978).

    PubMed  CAS  Google Scholar 

  • Hamosh, M.: Breast milk fat: Origin and digestion. In S. Freier and A. I. Eidelman (eds.): Human milk. Its biological and social value, p. 62. Amsterdam-Ox ford-Princeton: Excerpta Medica (1980).

    Google Scholar 

  • Hapke, H. J.: Pestizide in der Frauenmilch. Umschau 10, 318 (1979).

    Google Scholar 

  • Harless, R. L., E. O. Oswald, M. K. Wilkinson, A. E. Bupury, D. P. McDaniel, and H. Tai: Sample preparation and gas chromatography-mass spectrometry determination of 2,3,7,8-tetrachlorodibenzo-p-dioxin. Anal. Chem. 52, 1239 (1980).

    PubMed  CAS  Google Scholar 

  • Harrod, J. R., and M. T. Asquith: Pollutants in breast milk. N. Eng. J. Med. 303, 945 (1980).

    CAS  Google Scholar 

  • Hashemy-Tonkabony, S. E., and F. Fateminassab: Chlorinated pesticide residues in milk of Iranian nursing mothers. J. Dairy Sci. 60, 1858 (1977).

    PubMed  CAS  Google Scholar 

  • Hashimoto, T. M.: Organochlorine pesticide residues in human breast milk. (In Japanese) Bull. Hyoga Prefect. Public Health Lab. 7, 19 (1972).

    Google Scholar 

  • Hattula, M. L., J. Ikkala, M. Isomäki, K. Määttä, and A. U. Arstila: Chlorinated hydrocarbon residues (PCB and DDT) in human liver, adipose tissue and brain in Finland. Acta Pharmacol. et Toxicol. 39, 545 (1976).

    CAS  Google Scholar 

  • Haver, W. van, R. Vandezande, and L. Gordts: Organochlorpesticiden in moedermelk. Belg. Med. Soc. Hyg. Med. Trav. Med. Leg. 35, 312 (1977).

    Google Scholar 

  • Hawthorne, J., J. H. Ford, C. D. Loftis, and G. P. Markin: Mirex in milk from southeastern United States. Bull. Environm. Contam. Toxicol. 11, 238 (1974).

    CAS  Google Scholar 

  • Hayashi, M.: Pollution of mother’s milk by organo chlorine pesticides. (In Japanese) Japan J. Publ. Health 19, 437 (1972 a).

    Google Scholar 

  • Hayashi, M.: Pesticide pollution of mother’s milk. (In Japanese) J. Japan Med. Assoc. 68, 1981 (1972 b).

    Google Scholar 

  • Hayes, W. J.: Dosage relationships associated with DDT in milk. Toxicol. Applied Pharmacol. 38, 19 (1976).

    CAS  Google Scholar 

  • Heeschen, W.: Analyses for residues in milk and milk products. In F. Coulston and F. Korte (eds.): EQS Environmental Quality and Safety 1, 229. Stuttgart: G. Thieme Verlag (1972).

    Google Scholar 

  • Heeschen, W., A. Blüthgen, und A. Tolle: Fremdstoffe in der Muttermilch. In Hövels, O., and I. Eckert (eds.): Säuglingsernährung in den ersten Lebensmonaten in Klinik und Praxis. Symposium BAD Nauheim, 1977. Stuttgart: G. Thieme Verlag (1978).

    Google Scholar 

  • Heeschen, W., A. Blüthgen, und A. Tolle: Toxikologische bewertung von HCH-Rückständen. Kiel Milchwirtsch Forschungsber. 32, 151 (1980).

    CAS  Google Scholar 

  • Heeschen, W., A. Blüthgen, and A. Tolle: Chlorierte Kohlenwasserstoffe in Frauenmilch. Molkereizeitung Welt Milch 36, 302 (1981).

    Google Scholar 

  • Hergenrather, J., G. Hlady, B. Wallace, and E. Savage: Pollutants in breast milk of vegetarians. N. Eng. J. Med. 304, 792 (1981).

    CAS  Google Scholar 

  • Herngreen, M. J. J., and R. L. Zielhuis: Borstvoeding en bestrijdungsmiddelen. Ned. T. Geneesk. 116, 511 (1972).

    PubMed  CAS  Google Scholar 

  • Hesse, V., T. Gabrio, E. Kirst, and W. Plenert: Untersuchungen zur Kontamination von Frauenmilch, Kuhmilch und Butter in der DDR mit chlorierten Kohlenwasserstoffen. Kinderarztl. Prax. 49, 292 (1981).

    PubMed  CAS  Google Scholar 

  • Heyndrickx, A., and R. Maes: The excretion of chlorinated insecticides inhuman mother milk. J. Pharm. Beg. 24, 459 (1969).

    CAS  Google Scholar 

  • Hidaka, K., Ohe, and K. Fujiwara: PCB and organochlorine pesticide in mother’s milk. (In Japanese) Igakuno Ayumi 82, 519 (1972).

    CAS  Google Scholar 

  • Hofvander, Y., and A. Petros-Barvazian: WHO collaborative study on breast feeding. Acta Paediatr. Scand. 67, 556 (1978).

    PubMed  CAS  Google Scholar 

  • Hofvander, Y., U. Hagman, C.-E. Linder, R. Vaz, and S. A. Slorach: WHO collaborative breast feeding study. I. Organochlorine contaminants in individual samples of Swedish human milk, 1978–1979. Acta Paediatr. Scand. 70, 3 (1981).

    PubMed  CAS  Google Scholar 

  • Holdrinet, M. V. H., H. E. Braun, R. Frank, G. J. Stopps, M. S. Smout, and J. W. McWade: Organochlorine residues in human adipose tissue and milk from Ontario residents, 1969–74. Can. J. Publ. Health 68, 74 (1977).

    CAS  Google Scholar 

  • Hornabrook, R. W., P. G. Dyment, E. D. Gomes, and J. S. Wiseman: DDT residues in human milk from New Guinea natives. Med. J. Aust. 1, 1297 (1972).

    PubMed  CAS  Google Scholar 

  • Hruska, J.: DDT residues in the milk, butter, and fat of cattle. (In Czech.) Veter-inarstvi. 19, 493 (1969).

    Google Scholar 

  • Hunt, V. R.: Work and the health of women. Boca Raton, Florida: CRC Press (1979).

    Google Scholar 

  • IARC: Monographs on the evaluation of the carcinogen risk of chemicals to humans. Vol. 18: Polychlorinated biphenyls and polybrominated bi-phenyls. Lyon: International Agency for Research on Cancer (1978).

    Google Scholar 

  • IARC: Chemicals and industrial processes associated with cancer in humans. IARC Monographs, suppl. 1. Lyon: International Agency for Research on Cancer (1979).

    Google Scholar 

  • ICRP: International Commission on Radiation Protection. Report of the task group on reference man. Oxford: Pergamon (1975).

    Google Scholar 

  • Inoue, Y.: Discovery of PCB pollution in a textile factory. I. PCB levels in blood serum of laborers and results of physical examination. (In Japanese) Japan J. Publ. Health 22, 459 (1975).

    Google Scholar 

  • Inuyama, Y., and T. Takeshita: Organochlorine residues in mother’s milk and blood. (In Japanese) Prefect. Inst. Public Health 12, 27 (1970).

    Google Scholar 

  • Jelliffe, D. B., and E. F. P. Jelliffe: Human milk in the modern world. Oxford: Oxford University Press (1979).

    Google Scholar 

  • Jensen, A. A., and K. F. Jørgensen: Polychlorinated terphenyls (PCTs). Use, levels and biological effects. Sci. Total Environ. In press (1983).

    Google Scholar 

  • Jensen, R. G., R. M. Clark, and A. M. Ferris: Composition of the lipids in human milk: A review. Lipids 15, 345 (1980).

    PubMed  CAS  Google Scholar 

  • Jensen, S.: The PCB story. Ambio 1, 123 (1972).

    CAS  Google Scholar 

  • Jensen, S., and G. Sundström: Structures and levels of most chlorobiphenyls in two technical PCB products and in human adipose tissue. Ambio 3, 70 (1974).

    CAS  Google Scholar 

  • Jonas, A.: Human milk at different stages of lactation. In S. Freier and A. I. Eidelman (eds.): Human milk. Its biological and social value, p. 51. Amster-dam-Oxford-Princeton: Excerpta Medica (1980).

    Google Scholar 

  • Jonsson, V., G. J. K. Liu, J. Armbruster, L. L. Kettelhut, and B. Drucker: Chlorohydrocarbon pesticide residues in human milk in Greater St. Louis, Missouri 1977. Amer. J. Clin. Nutr. 30, 1106 (1977).

    PubMed  CAS  Google Scholar 

  • Jugo, S.: Metabolism of toxic heavy metals in growing organisms: A review. Environ. Res. 13, 36 (1977).

    PubMed  CAS  Google Scholar 

  • Jukes, T. H.: DDT in mothers milk. Nature 226, 194 (1970).

    PubMed  CAS  Google Scholar 

  • Juszkiewicz, T.: Toksykologia Srodowskowa Zagrozeń Przed I Poporadowych. Genekol. Pol. Suppl. 1, 14 (1979).

    Google Scholar 

  • Juszkiewicz, T., A. Niewiadowska, and T. Radomanski: Polychlorinated biphenyls in human milk from three different regions of the country. (In Polish) Bromat. Chem. Toksykol., 10, 263 (1977).

    CAS  Google Scholar 

  • Juszkiewicz, T., J. Stec, A. Niewiadowska, and A. Posyniak: Pesticide residues in animal tissues in the light of 11-year studies. Mater. Ses. Inst. Ochr. Rosl. 14, 211 (1980).

    Google Scholar 

  • Kaiser, K. L. E.: The rise and fall of Mirex. Environ. Sci. Technol. 12, 520 (1978).

    CAS  Google Scholar 

  • Kalra, R. L., and R. P. Chawla: Occurrence of DDT and BHC residues in human milk in India. Experientia 37, 404 (1981).

    PubMed  CAS  Google Scholar 

  • Kamata, T.: On the present status of environmental polllution by organo chlorine pesticide residues. (In Japanese) Japan J. Publ. Health 20, 405 (1973).

    Google Scholar 

  • Kamata, T.: Hygienic studies on pesticide residues. ( In Japanese) Med. J. Hiroshima Univ. 22, 315 (1974).

    Google Scholar 

  • Kanitz, S., and G. Castello: The presence of residues of some disenfectants in the human adipose tissue and in some foods. (In Italian) Igiene Med. Prev. 7, 1 (1966).

    CAS  Google Scholar 

  • Kasahara, M., and S.-I. Nosu: Über das sogenante “Normalblei” in der Frauenmilch. Jahrb. Kinderh. 145, 78 (1935).

    CAS  Google Scholar 

  • Kato, K., T. Yamada, and S. Watanabe: Analyses of residual pesticides in vegetables, cow milk and mothers milk. (In Japanese) Ann. Rept. Kanagawa. Prefect. Inst. Publ. Health 21, 85 (1971).

    Google Scholar 

  • Kavlock, R. J., N. Chernoff, E. Rogers, and D. Whitehouse: Comparative tissue distribution of mirex and chlordecone in fetal and neonatal rats. Pest. Bio-chem. Physiol. 14, 227 (1980).

    CAS  Google Scholar 

  • Kawai, Y., Y. Hori, Y. Nigawa, I. Yamamoto, Y. Tsuzuki, H. Kitayama, and K. Mori: On the pollution of mother’s milk by pesticides and PCB in Kok-kaido. (In Japanese) J. Food. Hyg. Soc. Japan 14, 310 (1973).

    Google Scholar 

  • Kay, K.: Polybrominated biphenyls (PBB) environmental contamination in Michigan, 1973–1976. Environ. Res. 13, 74 (1977).

    PubMed  CAS  Google Scholar 

  • Kehoe, R. A., F. Thamann, and J. Cholak; On the normal absorption and excretion of lead. IV. Lead absorption and excretion in infants and children. J. Ind. Hyg. 15, 301 (1933).

    CAS  Google Scholar 

  • Kendrick, E.: Testing for environmental contaminants in human milk. Pediatrics 66, 470 (1980).

    PubMed  CAS  Google Scholar 

  • Kimbrough, R. D., D. F. Groce, M. P. Korver, and V. W. Burse: Induction of liver tumors in female Sherman strain rats by polybrominated biphenyls. J. Nat. Cancer Inst. 66, 535 (1981).

    PubMed  CAS  Google Scholar 

  • Klemmer, H. E., A. M. Budy, and W. Takahashi: Human tissue distribution of cyclodiene pesticides-Hawaii 1964–73. Clin. Toxicol. 11, 71 (1977).

    PubMed  CAS  Google Scholar 

  • Knoll, W., and S. Jayaraman: Zur Kontamination von Humanmilch mit chlorierten Kohlenwasserstoffen. Nahrung 17, 599 (1973 a).

    CAS  Google Scholar 

  • Knoll, W., and S. Jayaraman: Chlorierte Kohlenwasserstoffe in Humanmilch. Z. Ges. Hyg. 19, 43 (1973 b).

    CAS  Google Scholar 

  • Kodoma, H., and H. Ota: Transfer of polychlorinated biphenyls to infants from their mothers. Arch. Environ. Health 35, 95 (1980).

    Google Scholar 

  • Kodric-Smit, M., Z. Smit, and K. Olie: Organochlorine contaminants in human milk from Slavonia Provence, Yugoslavia, 1978. Pest. Monit. J. 14, 1 (1980).

    CAS  Google Scholar 

  • Kojima, S., M. Saito, H. Konno, and K. Ozawa: Results of investigation of organochlorine pesticide residues in mother’s milk and in blood of the mothers. (In Japanese) Rept. Akita Prefect. Inst. Publ. Health 16, 65 (1971).

    Google Scholar 

  • Komarova, L.: DDT excretion with the breast milk and its effect on the body of the mother and child. (In Russian) Pediatr. Akus. Ginek. 1, 19 (1970).

    CAS  Google Scholar 

  • Kontek, M., S. Kubachi, S. Paradowski, and B. Wierzchowiecka: Determination of organic chlorine pesticides in human milk. (In Polish) J. Pediatr. Pol. 46, 193 (1971).

    Google Scholar 

  • Kontek, M., S. Banaszak, J. Didowicz-Parzycka, S. Kubacki, and A. Kossowski: Comparative investigations of organic chloride pesticides in human milk before and after withdrawal of these agents from chemical plant protection. Pol. Tyg. Lek. 36, 9 (1981).

    PubMed  CAS  Google Scholar 

  • Kostial, K., and D. Kello: Bioavailability of lead in rats fed “human” diets. Bull. Environm. Contam. Toxicol. 21, 312 (1979).

    CAS  Google Scholar 

  • Krauthacker, B., T. Alebic-Kolbah, A. Buntic, B. Tkalcevic, and E. Reiner: DDT residues in samples of human milk and in mothers and cord blood serum in a continental town in Croatia (Yugoslavia). Int. Arch. Occup. Environ. Health 46, 267 (1980).

    PubMed  CAS  Google Scholar 

  • Kroger, M.: Insecticide residues in human milk. J. Pediatr. 80, 401 (1972).

    PubMed  CAS  Google Scholar 

  • Kroger, M.: General environmental contaminants occurring in milk. In B. L. Larson and V. R. Smith (eds.): Lactation: A comprehensive treatise, p. 135. New York: Academic Press (1974).

    Google Scholar 

  • Kumpulainen, J.: Determination of chromium in human milk and urine by graphite-furnace atomic absorption spectrometry. Anal. Chim. Acta 113, 355 (1980).

    CAS  Google Scholar 

  • Kuratsune, M.: Epidemiologic studies on Yusho. In K. Higuchi (ed.): PCB poisoning and pollution, p. 9. Tokyo: Kodanska Ltd. (1976).

    Google Scholar 

  • Kutz, F. W., and S. C. Strassman: Residues of polychlorinated biphenyls in the general population of the United States. Conference Proceedings. Nat. Conf. of Polychlorinated Biphenyls, Chicago, 1975, p. 139. U.S. Environmental Protection Agency (EPA-560/6-75-004) (1976).

    Google Scholar 

  • Kutz, F. W., S. C. Strassman, and A. R. Yobs: Survey of pesticide residues and their metabolites in humans. Pest. Manage. Insectic. Resist., p. 523 (1977).

    Google Scholar 

  • Kutz, F. W., S. C. Strassman, and J. F. Sperling: Survey of selected organochlorine pesticides in the general population of the United States: Fiscal years 1970–1975. Ann. N.Y. Acad. Sci. 320, 60 (1979).

    PubMed  CAS  Google Scholar 

  • Kuwabara, K., T. Yakushiji, I. Watanabe, S. Yoshida, K. Koyama, and N. Kunita: Levels of polychlorinated biphenyls in blood of breast-fed children whose mothers are non-occupationally exposed to PCBs. Bull. Environm. Con-tarn. Toxicol. 21, 458 (1979).

    CAS  Google Scholar 

  • Lamm, S. H., and J. F. Rosen: Lead contamination in milks fed to infants: 1972–1973. Pediatr. 53, 137 (1974).

    CAS  Google Scholar 

  • Lamm, S. H., and J. F. Rosen: Blood lead concentrations among formula-fed and breast-fed infants. Amer. J. Epidem. 104, 312 (1976).

    Google Scholar 

  • Lamm, S. H., B. Cole, K. Glynn, and W. Ullmann: Lead content of milk fed to infants, 1971–2. N. Eng. J. Med. 289, 574 (1973).

    CAS  Google Scholar 

  • Landoui, J. H., and E. A. Astolfi: Organochlorinated pesticide residues in human milk—Rep. Argentina—10 years monitoring. Paper, Int. Symp., Chemicals in the Environment, Copenhagen, Oct. 18-20 (1982).

    Google Scholar 

  • Landrigan, P. J.: General population exposure to environmental concentrations of halogenated biphenyls. In R. Kimbrough (ed.): Halogenated biphenyls, terphenyls, nap hthalens, dibenzodioxines and related products, p. 267. Elsevier/North-Holland Biomedical Press (1980).

    Google Scholar 

  • Lamm, S. H., K. R. Wileox, J. Silva, H. E. B. Humphrey, C. Kauffman, and C. W. Heath: Cohort study of Michigan residents exposed to polybrominated biphenyls: epidemiologic and immunilogic findings. Ann. N.Y. Acad. Sci 320, 284 (1979).

    Google Scholar 

  • Landry, T. D., R. A. Doherty, and A. H. Gates: Effects of three diets on mercury excretion after methylmercury administration. Bull. Environm. Con-tarn. Toxicol. 22, 151 (1979).

    CAS  Google Scholar 

  • Langhorst, M. L., and L. A. Shadoff: Determination of parts-per-trillion concentrations of tetra-, hexa-, hepta-, and octachlorodibenzo-p-dioxins in human milk samples. Anal. Chem. 52, 2037 (1980).

    PubMed  CAS  Google Scholar 

  • Larsson, B., S. A. Slorach, U. Hagman, and Y. Hofvander: WHO collaborative breast feeding study, II. Levels of lead and cadmium in Swedish human milk 1978–79. Acta Pædiatr. Scand. 70, 281 (1981).

    PubMed  CAS  Google Scholar 

  • Laug, E. P., F. M. Kunze, and C. S. Prickett: Occurrence of DDT in human fat and milk. Arch. Industr. Hyg. 3, 245 (1951).

    CAS  Google Scholar 

  • Lechner, W., H. J. Battista, and F. Dienstl: Untersuchungen zum Bleigehalt in der Muttermilch in Verkehrsreichen und Verkehrsarmen Gegenden Tirols. Gynäk. Rdsch. (Suppl.) 20, 268 (1980).

    Google Scholar 

  • Lombeck, I., K. Kasperek, B. Bonnermann, L. E. Feinendegen, and H. J. Bremer: Selenium content of human milk, cow’s milk and cow’s milk infant formulas. Eur. J. Pediatr. 129, 139 (1978).

    PubMed  CAS  Google Scholar 

  • Lora, R. P., A. H. Marteache, L. M. P. Villar, R. L. Gimenez, M. J. Villarejo, and J. I. Perez: Plaquicidas organoclorados en leches humanas espanolas. Rev. Esp. Pediatr. 35, 93 (1979).

    Google Scholar 

  • Lorenzo, D. T., and M. I. F. Garcia: Determination de residues de pesticidas organoclorados en leche de mujer. Quim. Anal. 30, 319 (1976).

    Google Scholar 

  • Löfroth, G.: Who cares about DDT? Ecologist 1, 8 (1971).

    Google Scholar 

  • Lönnerdal, B., C. L. Keen, and L. S. Hurley: Iron, copper, zinc, and manganese in milk. Ann. Rev. Nutr. 1, 49 (1981).

    Google Scholar 

  • Luquet, F. M., J. Gorsaud, and B. Gaudier: Etude de la pollution des laits humains par les résidues de pesticides. Pathol. Biol 20, 137 (1972).

    PubMed  CAS  Google Scholar 

  • Luquet, F. M., J. Gorsaud, and J. Casalis: Pollution des laits de femme par les residus de pesticides organochlorés en France. Lait 55, 207 (1975).

    CAS  Google Scholar 

  • Lusby, W. R., and K. R. Hill: Detection of mirex in the presence of poly chlorinated biphenyls. Bull. Environm. Contam. Toxicol. 22, 567 (1979).

    CAS  Google Scholar 

  • McCormack, K. M., P. Melrose, D. E. Ricket, J. G. Dent, J. E. Gibson, and J. B. Hook: Concomitant dietary exposure to polychlorinated biphenyls and polybrominated biphenyls: Tissue distribution and arylhydrocarbon hydroxylase activity in lactating rats. Toxicol. Applied Pharmacol. 47, 95 (1979).

    CAS  Google Scholar 

  • McCormack, L. F. Lepper, D. M. Wilson, and J. B. Hook: Biochemical and physiological sequelae to perinatal exposure to polybrominated biphenyls: A multigeneration study in rats. Toxicol. Applied Pharmacol. 59, 300 (1981).

    CAS  Google Scholar 

  • Macy, I. G.: Composition of human colostrum and milk. Amer. J. Dis. Child. 78, 589 (1949).

    CAS  Google Scholar 

  • Mansour, M. M., N. C. Dyre, L. H. Hoffman, A. R. Schulert, and A. B. Brill: Maternal-fetal transfer of organic and inorganic mercury via placenta and milk. Environ. Res. 6, 479 (1973).

    PubMed  CAS  Google Scholar 

  • Maruna, H., R. F. L. Maruna, and R. Eisner: Cadmium und Blei in Muttermilchproben. Arztl. Praxis 28, 6 (1976).

    Google Scholar 

  • Masuda, Y., R. Kagawa, and M. Kuratsune: Comparison of polychlorinated biphenyls in Yusho patients and ordinary persons. Bull. Environm. Contam. Toxicol. 11, 212 (1974).

    Google Scholar 

  • Masuda, Y., R. Kagawa, H. Kuroki, M. Kuratsune, T. Yoshimura, I. Taki, M. Kusuda, F. Yamashita, and M. Hayashi: Transfer of polychlorinated biphenyls from mothers to foetuses and infants. Food Cosmet. Toxicol. 16, 543 (1978).

    PubMed  CAS  Google Scholar 

  • Masuda, Y., R. Kagawa, H. Kuroki, S. Tokudome, and M. Kuratsune: Transfer of various polychlorinated biphenyls to the foetuses and offspring of mice. Food Cosmet. Toxicol. 17, 623 (1979).

    PubMed  CAS  Google Scholar 

  • Matuo, Y. K., J. N. C. Lopes, and J. L. C. Lopes: DDT levels in human milk from Ribeiraõ Preto (Brazil). Rev. Brasil. Biol. 40, 293 (1980).

    PubMed  CAS  Google Scholar 

  • Mes, J.: Experiences in human milk analysis for halogenated hydrocarbon residues. Intern. J. Environ. Anal. Chem. 9, 283 (1981).

    CAS  Google Scholar 

  • Mes, J., and D. J. Davies: Variation in the polychlorinated biphenyl and organochlorine pesticide residues during human breastfeeding and its diurnal pattern. Chemosphere 9, 699 (1978).

    Google Scholar 

  • Mes, J., and D. J. Davies: Presence of polychlorinated biphenyl and organochlorine pesticide residues and the absence of polychlorinated terphenyls in Canadian human milk samples. Bull. Environm. Contam. Toxicol. 21, 381 (1979).

    CAS  Google Scholar 

  • Mes, J., and D. J. Davies, and P.-Y. Lau: The effects of extraction technique on the fat content, poly chlorinated biphenyl level and tri-to octabiphenyl distribution in human milk. Chemosphere 9, 763 (1980).

    CAS  Google Scholar 

  • Mes, J., and D. J. Davies: Poly chlorinated biphenyl in human milk samples from British Columbia (Canada) Women. Bull. Environm. Contam. Toxicol. In press (1982).

    Google Scholar 

  • Mes, J., and D. J. Davies, and W. Miles: Traces of mirex in some Canadian human milk samples. Bull. Environm. Contam. Toxicol. 19, 564 (1978).

    CAS  Google Scholar 

  • Mes, J., and D. J. Davies, and D. Turton: Poly chlorinated biphenyl and other chlorinated hydrocarbon residues in adipose tissue of Canadians. Bull. Environm. Contam. Toxicol. 28, 97 (1982).

    CAS  Google Scholar 

  • Miller, G. J., and J. A. Fox: Chlorinated hydrocarbon pesticide residues in Queensland human milk. Med. J. Aust. 2, 261 (1973).

    PubMed  CAS  Google Scholar 

  • Miller, H. J., S. Cucos, D. Wassermann, and M. Wassermann: Organochlorine insecticides and poly chlorinated biphenyls in human milk. In W. B. Deichmann (ed.): Toxicology and occupational medicine, p. 279. New York: Elsevier/North-Holland (1979).

    Google Scholar 

  • Minagawa, K., Y. Takigawa, H. Sakai, and I. Sasagawa: Poly chlorinated terphenyls in human fat and mothers milk. (In Japanese) Nippon Eiseigaha Zasshi. 28, 543 (1974); through Chem. Abstr. 82, 11876j (1975).

    CAS  Google Scholar 

  • Miyazaki, T., K. Akiyama, S. Kaneko, S. Horii, and T. Yamagishi: Chlordane residues in human milk. Bull. Environ. Contam. Toxicol. 25, 518 (1980).

    PubMed  CAS  Google Scholar 

  • Miyazaki, T., S. Kaneko, S. Horii, and T. Yamagishi: Identification of the synergist bis(2,3,3,3-tetrachloropropyl)ether in human milk. Bull. Environm. Contam. Toxicol. 26, 420 (1981).

    CAS  Google Scholar 

  • Mizoguchi, M., T. Yamagishi, F. Ushio, C. Fujimoto, K. Takeba, K. Kani, M. Haruta, K. Yasuhara, and H. Kubota: On the residual amount of organochlorine pesticides in human milk in Tokyo metropolitan area. (In Japanese) Japan J. Publ. Health 19, 541 (1972).

    Google Scholar 

  • Mølhave, L., I. Andersen, G. R. Lundquist, P. A. Nielsen, and O. Nielsen: Afgas-ning frabyggematerialer-Forekomst og hygiejnisk vurdering. SBI-rapport 137 Statens Byggeforskningsinstitut, København (1982).

    Google Scholar 

  • Mullin, M., G. Sawka, L. Safe, S. McCrindle, and S. Safe: Synthesis of octa-and nonachlorobiphenyl isomers and congeners and their quantitation in commercial polychlorinated biphenyls and identification in human breast milk. J. Anal. Toxicol. 5, 138 (1981).

    PubMed  CAS  Google Scholar 

  • Munro, I. C., and S. M. Charbonneau: Environmental contaminants. Fed. Proc. 37, 2582 (1978).

    PubMed  CAS  Google Scholar 

  • Murthy, G. K., and U. S. Rhea: Cadmium, copper, iron, lead, manganese, and zinc in evaporated milk, infant products, and human milk. J. Dairy Sci. 54, 1001 (1971).

    PubMed  CAS  Google Scholar 

  • Murti, C. R. G.: Etiologic studies. Environmental cancer in the Indian context. J. Cancer Res. Clin. Oncol. 99, 57 (1981).

    CAS  Google Scholar 

  • Musial, C. J., O. Hutzinger, V. Zitko, and J. Crocker: Presence of PCB, DDE and DDT in human milk in the provinces of New Brunswick and Nova Scotia, Canada. Bull. Environm. Contam. Toxicol. 12, 258 (1974).

    CAS  Google Scholar 

  • Müller, B., and H. Schröder: Biozide in menschlishem Fettgewebe und Muttermilch. Ernährungs-Umschau 25, 205 (1978).

    Google Scholar 

  • Nagai, I.: Residues of organochlorine pesticides in mothers milk in Yamaguchi Prefecture. (In Japanese) Ann. Rep. Res. Inst. Public Health 14, 93 (1972).

    Google Scholar 

  • Nakayama, K., and T. Aoki: Hazards of organic chlorine compounds to the health of children. Paediatr. 6, 9 (1977).

    CAS  Google Scholar 

  • Narayanan, I., K. Prakash, and V. V. Gujral: The value of human milk in the prevention of infection in the high risk low-birth-weight infant. J. Pediatr. 99, 496 (1981).

    PubMed  CAS  Google Scholar 

  • Newton, K. G., and N. C. Greene: Organochlorine pesticide residue levels in human milk. Pest. Monit. J. 6, 4 (1972).

    CAS  Google Scholar 

  • Noirfalise, A., C. Heusghem, and J. Legros: Teneur en plomb du lait humain et de produits de substitution. Arch. Belg. Med. Soc. 25, 73 (1967).

    PubMed  CAS  Google Scholar 

  • Ogra, P. L., and H. L. Greene: Human milk and breast feeding: An update on the state of the art. Pediatr. Res. 16, 266 (1982).

    PubMed  CAS  Google Scholar 

  • Olszyna-Marzys, A. E.: Contaminants in human milk. Acta Paediatr. Scand. 67, 571 (1978).

    PubMed  CAS  Google Scholar 

  • Olszyna-Marzys, A. E., M. Campos de, M. T. Farvar, and M. Thoman: Residous de plaguicidas clorados en la leche humana en Guatemala. Bol. Of Sanit. Panam. 74, 93 (1973).

    CAS  Google Scholar 

  • Orbaek, K.: Personal communication (1979).

    Google Scholar 

  • Orbaek, K.: Personal communication (1982).

    Google Scholar 

  • Orberg, J.: Placental and mammary transfer of two PCBs (2,4′,5-TCB and 2,2′,4, 4′,5,5′-HCB) and their effect on reproductive capacity in mice. Ambio 6, 278 (1976).

    Google Scholar 

  • Oura, H., H. Kobayashi, T. Oura, I. Senda, and K. Kubota: On the pollution of human milk by PCB and organochlorine pesticides. (In Japanese) J. Jpn. Assoc. Rural Med. 21, 300 (1972).

    Google Scholar 

  • Parkinson, A., L. W. Robertson, and S. Safe: Reconstituted human breast milk PCBs as potent inducers of aryl hydrocarbon hydroxylase. Biochem. Bio-phys. Res. Communication 96, 882 (1980).

    CAS  Google Scholar 

  • Pellizzari, E. D., T. D. Hartwell, B. S. H. Harris, R. D. Waddell, D. A. Whitaker, and M. D. Erickson: Purgeable organic compounds in mother’s milk. Bull. Environm. Contam. Toxicol. 28, 322 (1982).

    CAS  Google Scholar 

  • Pesendorfer, H.: Rückstände von Organochlorpestiziden (DDT v.a.) und polychlorierten Biphenylen (PCB’s) in der Muttermilch. Klin. Wochenschr. 87, 732 (1975).

    CAS  Google Scholar 

  • Peters, H. A., S. A. M. Johnson, S. Cam, S. Oral, and T. Müftü: Hexachloroben-zene-induced porphyria: Effect of chelation on the disease, porphyrin and metal metabolism. Amer. J. Med. Sci. 251, 314 (1966).

    PubMed  CAS  Google Scholar 

  • Peters, H. A., A. Gocmen, D. J. Cripps, G. T. Bryan, and I. Dogramaci: Epidemiology of hexachlorobenzene-induced porphyria in Turkey: Clinical and laboratory follow-up after 25 years. Arch Neurol. 39, 744 (1982).

    PubMed  CAS  Google Scholar 

  • Pfeilsticker, K.: Pesticide in der Kinderernährung. Mschr. Kinderheilk. 121, 551 (1973).

    PubMed  CAS  Google Scholar 

  • Picciano, M. F., and H. A. Guthrie: Copper, iron and zinc contents of mature human milk. Amer. J. Clin. Nutr. 29, 242–54 (1974).

    Google Scholar 

  • Picciano, M. F., and H. A. Guthrie: The volume and composition of human milk. Lecture. Int. Symp. on infant and early childhood feeding. Michigan State University, Oct. (1978 a).

    Google Scholar 

  • Picciano, M. F., and H. A. Guthrie: Mineral content of human milk during a single nursing. Nutr. Rept. Int. 18, 5 (1978 b).

    CAS  Google Scholar 

  • Pinkerton, C., D. I. Hammer, K. Bridbord, J. P. Creason, J. L. Kent, and G. K. Murthy: Human milk as dietary source of cadmium and lead. In D. D. Hemphill (ed.): Trace substances in environmental health VI, pp. 39–44. University of Missouri, Colombia, MO (1972).

    Google Scholar 

  • Pitkin, R. M., J. A. Bahns, L. J. Filer, and W. A. Reynolds: Mercury in human maternal and cord blood, placenta, and milk. Proc. Soc. Exp. Biol. Med. 151, 565 (1976).

    PubMed  CAS  Google Scholar 

  • Poland, R. L., and S. N. Cohen: The contamination of the food chain in Michigan with PBB: The breast-feeding question. In: Drug and chemical risks to the fetus and newborn, p. 129. New York: A. R. Liss, Inc. (1980).

    Google Scholar 

  • Polishuk, Z., M. Ron, M. Wasserman, S. Cucos, D. Wasserman, and C. Lemesch: Organochlorine compounds in human blood plasma and milk. Pest. Monit. J. 10, 121 (1977).

    CAS  Google Scholar 

  • Prentice, A., A. M. Prentice, and R. G. Whitehead: Breast-milk fat concentrations of most African women. 1. Short-term variation within individuals. Br. J. Nutr. 45, 483 (1981 a).

    PubMed  CAS  Google Scholar 

  • Prentice, A., A. M. Prentice, and R. G. Whitehead: Breast-milk fat concentration of most African women. 2. Long-term variations within a community. Br. J. Nutr. 45, 495 (1981 b).

    PubMed  CAS  Google Scholar 

  • Prinz, B., J. Hower, and E. Gono: Erhebungen über den Einluss der bleiimissions-Belastung auf den Blutbleispiegel und die neurologische Entwicklung von Säuglingen im Westlichen Ruhrgebiet. Staub-Reinhalt. Luft. 38, 87 (1978).

    CAS  Google Scholar 

  • Pröstler, E.: Stillen trotz verseuchter Umwelt? Die chemische Belastung der Humanmilch. Freiburg: Dreisam-Verlag (1981).

    Google Scholar 

  • Quinby, E., J. F. Armstrong, and W. F. Durham: DDT in human milk. Nature 207, 726 (1965).

    PubMed  CAS  Google Scholar 

  • Rabar, I., and K. Kostial: Bioavailability of cadmium in rats fed various diets. Arch. Toxicol. 47, 63 (1981).

    PubMed  CAS  Google Scholar 

  • Raie, R. M., and H. Smith: Trace element deficiency and cot deaths. Med. Sci. Law. 21, 41 (1981).

    PubMed  CAS  Google Scholar 

  • Rappl, A., and W. Waiblinger: Zur Kontamination von Muttermilch mit Rückständen chlorierter Kohlwasserstoffe. Dtsch. Med. Wschr. 100, 228 (1975).

    PubMed  CAS  Google Scholar 

  • Reed, C. B.: A study of the conditions that require the removal of the child from the breast. Surg. Gynecol. Obstet. 6, 514 (1908).

    Google Scholar 

  • Reuber, M. D.: Carcinogenicity of benzene hexachloride and its isomers. J. Environ. Pathol. Toxicol. 4, 355 (1980).

    PubMed  CAS  Google Scholar 

  • Ritcey, W. R., G. Savary, and K. A. McCully: Organochlorine insecticide residues in human milk, evaporated milk and some milk substitutes in Canada. Can. J. Publ. Health 63, 125 (1972).

    CAS  Google Scholar 

  • Rodin, F.: Chlorerede insecticider i kvindemælk og komælk. Aarhus Levneds-middelkontrol, Aarhus (1968).

    Google Scholar 

  • Roels, H., R. Lauwerys, J.-P. Buchet, and G. Hubermont: Effects of lead on lactating rats and their sucklings. Toxicol. 8, 107 (1977).

    CAS  Google Scholar 

  • Rogan, W. J., A. Bagniewska, and T. Damstra: Pollutants in breast milk. N. Eng. J.Med. 302, 1450 (1980).

    CAS  Google Scholar 

  • Rosival, L., A. Szokolay, and J. Uhnak: Ökotoxikologische Studien über chlorierte Pestizide. Nahrung 24, 359 (1980).

    PubMed  CAS  Google Scholar 

  • Ryu, J. E., E. E. Ziegler, and S. J. Fomon: Maternal lead exposure and blood lead concentration in infancy. J. Pediatr. 93, 476 (1978).

    PubMed  CAS  Google Scholar 

  • Sasaki, S., K. Watabe, S. Hayashi, and H. Sugaya: Residues of organochlorine pesticides and PCBs in humans. (In Japanese) J. Japan Assoc. Rural Med. 29, 564 (1980).

    Google Scholar 

  • Savage, E. P.: National study to determine levels of chlorinated hydrocarbon insecticides in human milk. Washington: Environmental Protection Agency (EPA 540/9-781005) (1976).

    Google Scholar 

  • Savage, E. P., J. D. Tessari, J. W. Malberg, H. W. Wheeler, and J. R. Bagby: A search for polychlorinated biphenyls in human milk in rural Colorado. Bull. Environm. Contam. Toxicol. 9, 222 (1973 a).

    CAS  Google Scholar 

  • Savage, E. P., J. D. Tessari, J. W. Malberg, H. W. Wheeler, and J. R. Bagby: Organochlorine pesticide residues and polychlorinated biphenyls in human milk. Colorado 1971–72. Pest. Monit. J. 7, 1 (1973 b).

    CAS  Google Scholar 

  • Savage, E. P., J. D. Tessari, J. W. Malberg, H. W. Wheeler, and J. R. Bagby: A search for polychlorinated biphenyls in human milk in rural Colorado. In D. D. Hemphill (ed.): Trace substances in environmental health VI, pp. 45–48. Univ. Missouri, Columbia, MO (1972).

    Google Scholar 

  • Savage, E. P., T. J. Keefe, J. D. Tessari, H. W. Wheeler, F. M. Applehans, E. A. Goes, and S. A. Ford: National study of chlorinated hydrocarbon insecticide residues in human milk. USA Amer. J. Epidemiol. 113, 413 (1981).

    CAS  Google Scholar 

  • Schulte-Löbbert, F. J., and G. Bonn: Determination of cadmium in human milk during lactation. Arch. Toxicol. 37, 155 (1977).

    PubMed  Google Scholar 

  • Schüpbach, M. R., and H. Egli: Organochlorpestizide und poly chlorierte Bi-phenyle in Muttermilch. Mitt. Gebiete Lebensm. Hyg. 70, 451 (1979).

    Google Scholar 

  • Shearer, T. R., and D. M. Hadjimarkos: Geographic distribution of selenium in human milk. Arch. Environ. Health 30, 230 (1975).

    PubMed  CAS  Google Scholar 

  • Shimada, T., and M. Ugawa: Induction of liver microsmal drug metabolism by polychlorinated biphenyls whose gas Chromatographic profile have much in common with that in human milk. Bull. Environm. Contam. Toxicol. 20, 198 (1978).

    Google Scholar 

  • Shirakawa, M.: On the result of investigation of the pesticide residues in the milk from lactating women of coastal areas in Wakayama Prefecture. (In Japanese) Nippon Eiseigaku Zasshi 29, 94 (1974); through Pest. Abstr. 7, 74-1574 (1974).

    Google Scholar 

  • Siddiqui, M. K. J., M. C. Saxena, A. K. Bhargava, T. D. Seth, C. R. K. Murti, and D. Kutty: Agrochemicals in the maternal blood, milk, and cord blood: A source of toxicants for prenates and neonates. Environ. Res. 24, 24 (1981).

    PubMed  CAS  Google Scholar 

  • Siyali, D. S.: Polychlorinated biphenyls, hexachlorobenzene and other organochlorine pesticides in human milk. Med. J. Aust. 17, 815 (1973).

    Google Scholar 

  • Skaare, J. U.: Persistent organochlorinated compounds in Norwegian human milk in 1979. Acta Pharmacol, et Toxicol. 49, 384 (1981).

    CAS  Google Scholar 

  • Soos, K., and V. Czieleszky; Information submitted to WHO Regional Office for Europe, Copenhagen (1982).

    Google Scholar 

  • Stacey, I., and B. W. Thomas: Organochlorine pesticide residues in human milk, Western Australia—1970–71. Pest. Monit. J. 9, 64 (1975).

    CAS  Google Scholar 

  • Strassmann, S. C., and F. W. Kutz: Insecticide residues in human milk from Arkansas and Mississippi, 1973–74. Pest. Monit. J. 10, 130 (1977).

    Google Scholar 

  • Stross, J. K., I. A. Smokier, J. Isbister, and K. R. Wilcox: The human health effects of exposure to polybrominated biphenyls. Toxicol. Applied Pharmacol. 58, 145 (1981).

    CAS  Google Scholar 

  • Sugaya, T. et al.: Organochlorine pesticide residues in human milk. (In Japanese) J. Japan Assoc. Rural Med. 19, 379 (1971).

    Google Scholar 

  • Suvak, L. N.: DDT in mother’s milk. (In Russian) Adravoochr. Kosinev. 13, 19 (1970).

    CAS  Google Scholar 

  • Suzuki, Y., H. Sugaya, and S. Sasaki: Results of 3 years tracing investigations of organochlorine pesticide residues in humans. (In Japanese) J. Japan Assoc. Rural Med. 22, 276 (1973).

    Google Scholar 

  • Szokolay, A., L. Rosival, J. Uhnak, and A. Madaric: Dynamics of benzene hexa-chloride (BHC) isomers and other chlorinated pesticides in the food chain and in human fat. Ecotoxic. Envir. Safety 1, 349 (1977).

    CAS  Google Scholar 

  • Takagi, Y., T. Otake, M. Kataoka, Y. Murata, S. Aburada, S. Akasaka, K. Hashimoto, H. Uda, and T. Kitaura: Studies on the transfer and distribution of (14C) polychlorinated biphenyls from maternal to fetal and suckling rats. Toxicol. Applied Pharmacol. 38, 549 (1976).

    CAS  Google Scholar 

  • Takahashi, W., D. Saidin, G. Takei, and L. Wong: Organochlorine pesticide residues in human milk in Hawaii, 1979–80. Bull. Environm. Contam. Toxicol. 27, 506 (1981).

    CAS  Google Scholar 

  • Takeshita, R., M. Suzuki, and M. Hayashi: Transference of polychlorinated biphenyls in human adipose tissue to human milk. (In Japanese) Eisei Kagaku 20, 256 (1974); through Chem. Abstr. 82, 119751d (1975).

    CAS  Google Scholar 

  • Task Group on Metal Accumulation: Accumulation of toxic metals with special reference to their absorption, excretion and biological half-times. Environ. Physiol. Biochem. 3, 65 (1973).

    Google Scholar 

  • Tessari, J. D., and E. P. Savage: Pesticide residues. Gas-liquid Chromatographic determination of organochlorine pesticides and polychlorinated biphenyls in human milk. J. Assoc. Off. Anal. Chemists 63, 736 (1980).

    CAS  Google Scholar 

  • Thielemann, H.: Untersuchungsbegnisse zur Frage der Kontamination von Humanmilch mit Gesamt-DDT (DDT + DDE) im Stadtgebiet von Halle (Saale) im Jahre 1978. Pharmazie 34, 665–666 (1974).

    Google Scholar 

  • Thielemann, H., and H. Grahneis: Untersuchungserbegnisse zur Frage der Kontamination von Humanmilch mit Gesamt-DDT (DDT + DDE) im Stadtgebiet von Halle im Jahre 1976. Z. Ges. Hyg. 22, 68 (1978 a).

    Google Scholar 

  • Thielemann, H., and H. Grahneis: Untersuchungsergebnisse zur Frage der Kontamination von Humanmilch mit Gesamt-DDT (DDT + DDE) im Stadtgebiet von Halle im Jahre 1977. Pharmazie 33, 374 (1978 b).

    PubMed  CAS  Google Scholar 

  • Thielemann, H., H. Grahneis, and H. H. Haase: Untersuchungen zur Frage der Kontamination von Humanmilch mit DDT im Stadtgebiet von Halle. Z. Ges. Hyg. 21, 685 (1975).

    CAS  Google Scholar 

  • Tokutsu, K., T. Koyama, and T. Tokoyama: Pesticide residues in mother’s milk and plasma in Wakayama Prefecture. (In Japanese) Ann. Rep. Wakayama Prefect. Inst. Public Health 19, 59 (1970).

    Google Scholar 

  • Tolle, A., W. Heeschen, and A. Blüthgen: Fremdstoffe in Milchnahrungen. Mschr. Kinderheilk. 122, 309 (1974).

    PubMed  CAS  Google Scholar 

  • Tracy, A., and J. McPheat: Spectrographic determination of lead in blood. Bio-chem. J. 37,683 (1943).

    CAS  Google Scholar 

  • Tuinstra, L. G. M. Th.: Organochlorine insecticide residues in human milk in the Leiden region. Neth. Milk Dairy J. 25, 24 (1971 a).

    CAS  Google Scholar 

  • Tuinstra, L. G. M. Th.: Residuen van Organochloor Bestrijdingsmiddelen in Moedermelk in Leiden en Omgering. Voeding 32, 395 (1971 b).

    CAS  Google Scholar 

  • UNEP/WHO: Pilot project on assessment of human exposure topollutants through biological monitoring. Report of a consultation on the organochlorine compounds component, Zagreb, 8–11 Dec. (1981).

    Google Scholar 

  • UNEP/WHO: Report of a meeting of government designated experts on health-related monitoring. Geneva, 8–12 Mar. (1982).

    Google Scholar 

  • Unger, M., L. Ipsen, and J. Clausen: Forekomsten af polyklorerede bifenyler i human ammemælk, komælksprodukter samt i kostprøver. Ugeskr. Læger 144, 1849 (1982).

    PubMed  CAS  Google Scholar 

  • Unterman, H. W., and H. Aizicovici: Impregnation de DDT et DDE de l’organisme de la femme pendant la purepéralité. Igiena 21, 477 (1972).

    Google Scholar 

  • Unterman, H. W., and E, Sirghie: Impregnation of the human organism with organochlorine compounds. Determination of the DDT and DDE content in maternal milk. (In Romanian) Igiena 18, 221 (1969); through Excerpta Medica, Section 17, 16, 420 (1970).

    CAS  Google Scholar 

  • Varo, P., M. Nuurtamo, E. Saari, and P. Koivistoinen: Mineral element composition of Finnish foods. VII. Dairy products, eggs and margarine. Acta Agr. Scand. Suppl. 22, 115 (1980).

    CAS  Google Scholar 

  • Villar, L. M. P., A. H. Marteache, R. P. Lora, R. L. Gimenez, M. J. Villarejo, and J. I. Perez: Hexachlorobenzeno (HCB) en leches humanas espanolas. Rev. Esp. Pediatr. 35, 271 (1979).

    Google Scholar 

  • Vodicnik, M. H., and J. J. Lech: The transfer of 2,4,5,2′4′,5′-hexachlorobiphenyl to fetuses and nursing offspring. Toxicol. Applied Pharmacol. 54, 293 (1980).

    CAS  Google Scholar 

  • Vodicnik, M. H., C. R. Elcombe, and J. J. Lech: The transfer of 2,4,5,2′,4′,5′-hexa-chlorobiphenyl to fetuses and nursing offspring. Toxicol. Applied Pharmacol. 54, 301 (1980).

    CAS  Google Scholar 

  • Vozoveya, M. A., L. K. Malarova, and P. M. Enikeeva: Content of methylene chloride in tissues during pregnancy and lactation in female workers in rubber industry. (In Russian) Gig. Tr. Prof. Zabol. 18, 42 (1974).

    Google Scholar 

  • Vuori, E., H. Tyllinen, P. Kuitunen, and A. Paganus: The occurrence and origin of DDT in human milk. Acta Pædiatr. Scand. 66, 761 (1977).

    PubMed  CAS  Google Scholar 

  • Vuori, E., S. M. Mäkinen, R. Kara, and P. Kutiunen: The effects of the dietary intakes of copper, iron, manganese and zinc on the trace element content of human milk. Amer. J. Clin. Nutr. 33, 227 (1980).

    PubMed  CAS  Google Scholar 

  • Wada, Y., K. Iida, Y. Saito, and S. Watanabe: Contamination of human milk with polychlorinated biphenyls (PCB). (In Japanese) Kanagawa-Ken Eisei Kenkyusho Nempo 22, 102 (1972).

    Google Scholar 

  • Walker, B.: Lead content of milk and infant formula. J. Food Protec. 43, 178 (1980).

    CAS  Google Scholar 

  • Wasserman, M., D. Wasserman, S. Cucos, H. J. Miller, and N. Y. Ann: World PCB’s map. Ann. N.Y. Acad. Sci. 320, 69 (1979).

    Google Scholar 

  • Watanabe, I., T. Yakushiji, K. Kuwabara, S. Yoshida, K. Maeda, T. Kashimoto, K. Koyama, and N. Kunita: Surveillance of the daily PCB intake from diet of Japanese women from 1972–76. Arch. Environm. Contam. Toxicol. 8, 67 (1979).

    CAS  Google Scholar 

  • Watanabe, I., T. Yakushiji, and N. Kunita: Distribution differences between polychlorinated terphenyls and polychlorinated biphenyls in human tissues. Bull. Environm. Contam. Toxicol. 25, 810 (1980).

    CAS  Google Scholar 

  • Waters, E. M., J. E. Huft, and H. B. Gerstner: Mirex. An overview. Environ. Res. 14, 212 (1977).

    CAS  Google Scholar 

  • Wegman, R. C. C., and P. A. Greve: Levels of organochlorine pesticides and inorganic bromide in human milk. Meded. Fac. Landbouw Rijk Gent. 39, 1301 (1974).

    CAS  Google Scholar 

  • Weigand, G., and W. Mücke: Verunreinigung der Humanmilch mit Organohalo-genverbindungen. München: Gesellschaft für Strahlen und Umweltforschung (1980).

    Google Scholar 

  • Weisenberg, E., E. Ackerman, S. Freier, A. Reshef, Z. Sahm, and J. Shoenberg: Pesticides in the milk of mothers in Jerusalem. In S. Freier and A. I. Eidelman: Human milk—its biological and social value, p. 147. Amsterdam-Oxford-Princeton: Excerpta Medica. (1980).

    Google Scholar 

  • West, I.: Pesticides as contaminants. Arch. Environ. Health 9, 626 (1964).

    PubMed  CAS  Google Scholar 

  • West, R. W., D. J. Wilson, and W. Schaffner: Hexachlorophene concentrations in human milk. Bull. Environ. Contam. Toxicol. 13, 167 (1975).

    PubMed  CAS  Google Scholar 

  • Westöö, G., and K. Norén: Halter av klorpesticider och polykorerade bifenyler i svensk modermjölk. Vår Föda 24, 41 (1972).

    Google Scholar 

  • Westöö, G., and K. Norén: Kvicksilver och kvicksilverhalter i svensk komjölk och modersmjölk. Vår Föda 25, 122–123 (1974).

    Google Scholar 

  • Westöö, G., and K. Norén: Changes in the levels of environmental pollutants (Hg, DDT, Dieldrin, PCB) in some Swedish foods. Ambio 3, 79 (1974).

    Google Scholar 

  • Westöö, G., and K. Norén: Organochlorine contaminants in human milk, Stockholm, 1967–1977. Ambio 7, 62 (1978).

    Google Scholar 

  • WHO: The hazards to health and ecological effects of persistent substances in the environment-Polychlorinated biphenyls. Report on a Working Group. Regional Office for Europe. Copenhagen: World Health Organization (1975).

    Google Scholar 

  • WHO: Environmental Health Criteria 2: Polychlorinated biphenyls and terphenyls. Geneva: World Health Organization (1976).

    Google Scholar 

  • WHO: Environmental Health Criteria 9: DDT and its derivatives. Geneva: World Health Organization (1979).

    Google Scholar 

  • WHO: Contemporary pattern of breast-feeding. Geneva: World Health Organization (1981).

    Google Scholar 

  • Wickizer, T. M., and L. B. Brilliant: Testing for polychlorinated biphenyls in human milk. Pediatr. 68, 411 (1981).

    CAS  Google Scholar 

  • Wickizer, T. M., L. B. Brilliant, R. Copeland, and R. Tilden: Polychlorinated biphenyl contamination of nursing mother’s milk in Michigan. Amer. J. Publ. Health 71, 132 (1981).

    CAS  Google Scholar 

  • Wilson, J. T., R. D. Brown, D. R. Sherek, J. W. Dailey, B. Hilman, P. C. Jobe, B. R. Manno, J. E. Manno, H. M. Redtzki, and J. J. Stewart: Drug excretion in human breast milk. Principles, pharmacokinetics and projected consequences. Clin. Pharmacokin. 5, 1 (1980).

    CAS  Google Scholar 

  • Wilson, J. W., D. J. Locker, C. A. Ritzen, J. T. Watson, and W. Schaffner: DDT concentrations in human milk. Amer. J. Dis. Child. 125, 814 (1973).

    PubMed  CAS  Google Scholar 

  • Winter, M., M. Thomas, S. Wernick, S. Levin, and M. T. Farvar: Analysis of pesticide residues in 290 samples of Guatemalan mother’s milk. Bull. Envi-ronm. Contam. Toxicol. 16, 652 (1976).

    CAS  Google Scholar 

  • Wolff, M. S., H. A. Anderson, K. D. Rosenman, and I. J. Selikoff: Equilibrium of polybrominated biphenyl (PBB) residues in serum and fat of Michigan residents. Bull. Environm. Contam. Toxicol. 21, 775 (1979).

    CAS  Google Scholar 

  • Woodard, B. T., B. B. Ferguson, and D. J. Wilson: DDT levels in milk of rural indigent blacks. Amer. J. Dis. Child. 130, 400 (1976).

    PubMed  CAS  Google Scholar 

  • Wright, L. H., R. G. Lewis, H. L. Christ, G. W. Sovocool, and J. M. Simpson: The identification of polychlorinated terphenyls at trace levels human adipose tissue by gas chromatography/mass spectrometry. J. Anal. Toxicol. 2, 76 (1978).

    CAS  Google Scholar 

  • Yakushiji, T., R. Tanaka, and N. Kunita: PCB and organochlorine pesticides in mothers milk, blood and foods. Pediatr. 6, 28 (1977).

    CAS  Google Scholar 

  • Yakushiji, T., I. Watanabe, K. Kuwabara, and S. Yoshida: Identification of low chlorinated biphenyls in human milk by gas chromatography-mass spectrometry. J. Chromatog. 154, 203 (1978 a).

    CAS  Google Scholar 

  • Yakushiji, T., I. Watanabe, K. Kuwabara, and S. Yoshida, K. Koyama, I. Hara, and N. Kunita: Long term studies of the excretion of polychlorinated biphenyls (PCB) through the mother’s milk of an occupationally exposed worker. Arch. Environm. Contam. Toxicol. 7, 493 (1978 b).

    CAS  Google Scholar 

  • Yakushiji, T., I. Watanabe, K. Kuwabara, S. Yoshida, K. Koyama, and N. Kunita: Levels of polychlorinated biphenyls (PCBs) and organochlorine pesticides in human milk and blood. Int. Arch. Occup. Environ. Health 43, 1 (1979).

    PubMed  CAS  Google Scholar 

  • Yamagishi, T., K. Takeba, C. Fujimoto, K. Morimoto, and M. Haruta: On the organochlorine pesticide residues in mother’s body and her fetus’ body. (In Japanese) Tokyo Publ. Health Stud. 50, 44 (1972).

    Google Scholar 

  • Yoshida, S.,and A. Nakamura: Residual status after parturition of methylsulfone metabolites of polychlorinated biphenyls in the breast milk of a former employee in a capacitor factory. Bull. Environm. Contam. Toxicol. 21, 111 (1979).

    CAS  Google Scholar 

  • Yoshimura, T.: Epidemiological study on yusho babies born to mothers who had consumed oil contaminated by PCB. (In Japanese) Fukuoka Acta Med. 65, 74 (1974).

    Google Scholar 

  • Zaldivar, R., and G. Ghai: Clinical epidemiological studies on endemic chronic arsenic poisoning in children and adults, including observations on children with high-and low-intake of dietary arsenic. Zbl. Bakt. Hyg. I. Abt. Orig. 170, 409 (1980).

    CAS  Google Scholar 

  • Zimmerman, A. W.: Acrodermatitis in breast-fed premature infants: Evidence for a defect of mammary zinc secretion. Pediatr. 69, 176 (1982).

    CAS  Google Scholar 

  • Zitko, V.: PCB levels in human adipose tissue and population density. Chemosphere. 2, 45 (1979).

    Google Scholar 

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Jensen, A.A. (1983). Chemical contaminants in human milk. In: Gunther, F.A., Gunther, J.D. (eds) Residue Reviews. Residue Reviews, vol 89. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-5601-4_1

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