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Methyl bromide

  • Conference paper
Residue Reviews

Part of the book series: Residue Reviews ((RECT,volume 88))

Abstract

The first case of human poisoning by methyl bromide was reported by Schuler in 1899. Since then over 950 poisoning cases involving fatalities, systemic poisonings, skin injuries, and eye injuries have been reported in the United States, Canada, England, France, Germany, Belgium, The Netherlands, Spain, Switzerland, India, Iraq, Japan, Australia, and the Soviet Union. The medical personnel reporting these incidents were particularly concerned about the potential danger of methyl bromide because of the absence of warning properties, the delayed onset of toxicity, the severity of symptoms, the poor prognosis of patients, and the variety of central nervous system (CNS) effects observed. Damage to other organs, particularly the respiratory system, has also been noted. These case histories comprise the bulk of toxicologic information available on methyl bromide. Consequently, little is known concerning methyl bromide’s mechanism of toxic action in target organs or its actions on a cellular level. This information is not available although methyl bromide has been used extensively in agriculture for 50 years.

The authors thank Jean Ackerman for her assistance in preparation of this document and translations.

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  1. Department of Environmental Toxicology, University of California, Davis, CA, 95616, USA

    George V. Alexeeff & Wendell W. Kilgore*

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    Francis A. Gunther

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Alexeeff, G.V., Kilgore*, W.W. (1983). Methyl bromide. In: Gunther, F.A. (eds) Residue Reviews. Residue Reviews, vol 88. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-5569-7_3

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