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Preparing the Tracer: Iodination Techniques

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Book cover Assay of Calcium-regulating Hormones

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Abstract

Radiolabeled hormones have a wide variety of uses, for example in radioimmunoassay procedures, in pharmacokinetic analyses, as tracers for receptors, and for autoradiography studies. In general, it is not difficult to prepare radioiodinated hormones in the laboratory. However, iodination of parathyroid hormone (PTH) and calcitonin (CT) has been particularly troublesome because radiolabeling procedures often damage these hormones. With the development of several new techniques during the past decade, it is possible to choose the method best suited to the needs of the investigator.

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Authors
  1. Anne P. Teitelbaum
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Editors and Affiliations

  1. Department of Medicine, University of California, San Francisco Veterans Administration Medical Center, 4150 Clement Street (111N), 94121, San Francisco, California, USA

    Daniel D. Bikle M.D., Ph.D.

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© 1983 Springer-Verlag New York Inc.

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Teitelbaum, A.P. (1983). Preparing the Tracer: Iodination Techniques. In: Bikle, D.D. (eds) Assay of Calcium-regulating Hormones. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-5553-6_11

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  • DOI: https://doi.org/10.1007/978-1-4612-5553-6_11

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4612-5555-0

  • Online ISBN: 978-1-4612-5553-6

  • eBook Packages: Springer Book Archive

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