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Approaches to the Genetic Analysis and Breeding of Brewer’s Yeast

  • Chapter
Yeast Genetics

Abstract

Man has subjected many plants to breeding to suit his needs better. Some plant species have been bred for thousands of years. In modern times plant breeding has become increasingly intentional and systematic. Saccharomyces yeasts belong, according to their use, to man’s old, cultivated plants, but with the exception of pure culture selection (Hansen 1888) they have undergone little intentional or systematic breeding.

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References

  • Anderson, E., Martin, P. A. (1975). The sporulation and mating of brewing yeasts. J. Inst. Brew. 81:242–247.

    Google Scholar 

  • Barney, M. C., Jansen, G. P., Helbert, J. R. (1980a). Use of spheroplast fusion and genetic transformation to introduce dextrin utilization into Saccharomyces uvarum. Am. Soc. Brew. Chem. J. 38:1–5.

    CAS  Google Scholar 

  • Barney, M. C., Jansen, G. P., Helbert, J. R. (1980b). Use of genetic transformation for the introduction of flocculence into yeast. Am. Soc. Brew. Chem. J. 38:71–74.

    CAS  Google Scholar 

  • Beggs, J. D. (1978). Transformation of yeast by a replicating hybrid plasmid. Nature 275:104–109.

    Article  PubMed  CAS  Google Scholar 

  • Brown, A. J. P., Goodey, A. R., Tubb, R. S. (1981). Interstrain transfer of the 2µm DNA plasmid of Saccharomyces by cytoduction. J. Inst. Brew. 87:234–238.

    CAS  Google Scholar 

  • Burton, K. (1956). A study of the conditions and mechanism of the diphenylamine reaction for the colorimetrie estimation of deoxyribonucleic acid. Biochem. J. 62:315–323.

    PubMed  CAS  Google Scholar 

  • Cabane, B., Ramos-Jeunehomme, C., Lapage, N., Masschelein, C. A. (1974). Vicinal diketones—the problem and prospective solutions. Am. Soc. Brew. Chem. Proc. 1973:94–99.

    Google Scholar 

  • Cameron, J. R., Philippsen, P., Davis, R. W. (1977). Analysis of chromosomal integration and deletions of yeast plasmids. Nucl. Acids Res. 4:1429–1448.

    Article  PubMed  CAS  Google Scholar 

  • Christensen, B. E. (1979). Somatic hybridization in Saccharomyces cerevisiae: Analysis of products of protoplast fusion. Carlsberg Res. Commun. 44:225–233.

    Article  Google Scholar 

  • Clayton, E., Howard, G. A., Martin, P. A. (1973). Yeast hybridization. Am. Soc. Brew. Chem. Proc. 1972: 78–81.

    Google Scholar 

  • Conde, J., Fink, G. R. (1976). A mutant of Saccharomyces cerevisiae defective for nuclear fusion. Proc. Natl. Acad. Sci. USA 73:3651–3655.

    Article  PubMed  CAS  Google Scholar 

  • Conde Zurita, J., Mascort Suárez, J. L. (1981). Effect of the mitochondrial genome on the fermentation behaviour of brewing yeast. Eur. Brew. Conv. Congr., Copen-hagen, 177–186.

    Google Scholar 

  • Cryer, D. R., Eccleshall, R., Marmur, J. (1975). Isolation of yeast DNA. In: Methods in Cell Biology, edited by D. M. Prescott. New York: Academic Press, Vol. XII, pp. 39–44.

    Google Scholar 

  • Dutcher, S. K. (1981). Internuclear transfer of genetic information in karl-1/KAR1 heterokaryons in Saccharomyces cerevisiae. Mol. Cell. Biol. 1:245–253.

    PubMed  CAS  Google Scholar 

  • Emeis, C. C. (1961). Polyploide Kulturhefen. Eur. Brew. Conv. Congr., Wien, 205–215.

    Google Scholar 

  • Emeis, C. C. (1971). A new hybrid yeast for the fermentation of wort dextrins. Am. Soc. Brew. Chem. Proc. 58–62.

    Google Scholar 

  • Erratt, J. A., Stewart, G. G. (1978). Genetic and biochemical studies on yeast strains able to utilize dextrins. Am. Soc. Brew. Chem. J. 36:151–161.

    CAS  Google Scholar 

  • Fowell, R. R. (1969). Sporulation and hybridization of yeasts. In: The Yeasts, edited by A. H. Rose, J. S. Harrison. London and New York: Academic Press, Vol. 1, pp. 303–383.

    Google Scholar 

  • Gjermansen, C., Sigsgaard, P. (1981). Construction of a hybrid brewing strain of Saccharomyces carlsbergensis by mating of meiotic segregants. Carlsberg Res. Commun. 46:1–11.

    Article  CAS  Google Scholar 

  • Goodey, A. R., Tubb, R. S. (1981). A yeast gene responsible for the production of 4-vinyl guaiacol from ferulic acid. Soc. Gen. Microbiol. Quart. 8:103 (abstr.).

    Google Scholar 

  • Gunge, N., Nakatomi, Y. (1972). Genetic mechanisms of rare matings of the yeast Saccharomyces cerevisiae heterozygous for mating type. Genetics 70:41–58.

    PubMed  CAS  Google Scholar 

  • Gunge, N., Tamaru, A. (1978). Genetic analysis of products of protoplast fusion in Saccharomyces cerevisiae. Japan. J. Genet. 53:41–49.

    Article  Google Scholar 

  • Hansen, E. C. (1888). Undersogelser fra gjœringsindustriens praxis. Meddelelser fra Carlsberg Laboratoriet 2:257–322.

    Google Scholar 

  • Herbert, D., Phipps, P. J., Strange, R. E. (1971). Chemical analysis of microbial cells. In: Methods in Microbiology, edited by J. R. Norris, D. W. Ribbons. London and New York: Academic Press, Vol. 5B, pp. 209–344.

    Google Scholar 

  • Hinnen, A., Hicks, J. B., Fink, G. R. (1978). Transformation of yeast. Proc. Natl. Acad. Sci. USA 75:1929–1933.

    Article  PubMed  CAS  Google Scholar 

  • Holmberg, S. (1982). Genetic differences between Saccharomyces carlsbergensis and S. cerevisiae. II. Restriction endonuclease analysis of genes in chromosome III. Carlsberg Res. Commun. 47:233–244.

    Article  CAS  Google Scholar 

  • Holmberg, S., Kielland-Brandt, M. C., Nilsson-Tillgren, T., Petersen, J. G. L. (1979a). Molecular characterization of three his4 deletion mutants in Saccharomyces cerevisiae. Carlsberg Res. Commun. 44:283–288.

    Article  CAS  Google Scholar 

  • Holmberg, S., Petersen, J. G. L., Nilsson-Tillgren, T., Kielland-Brandt, M. C. (1979b). Molecular characterization of a Saccharomyces plasmid containing the HIS4 gene. Carlsberg Res. Commun. 44:269–282.

    Article  CAS  Google Scholar 

  • Jansen, G. P., Barney, M. C., Heibert, J. R., Esposito, M. S. (1979). Nonvectoras-sociated transformation in Saccharomyces. J. Appl. Biochem. 1:369–376.

    CAS  Google Scholar 

  • Johnston, J. R. (1965a). Breeding yeasts for brewing, I. Isolation of breeding strains. J. Inst. Brew. 71:130–135.

    Google Scholar 

  • Johnston, J. R. (1965b). Breeding yeasts for brewing, II. Production of hybrid strains. J. Inst. Brew. 71:135–137.

    Google Scholar 

  • Kielland-Brandt, M. C. (1981). The genetics of brewer’s yeast. Eur. Brew. Conv. Congr., Copenhagen, 263–276.

    Google Scholar 

  • Kielland-Brandt, M. C., Nilsson-Tillgren, T., Holmberg, S., Petersen, J. G. L., Svenningsen, B. A. (1979a). Transformation of yeast without the use of foreign DNA. Carlsberg Res. Commun. 44:77–87.

    Article  CAS  Google Scholar 

  • Kielland-Brandt, M. C., Petersen, J. G. L., Mikkelsen, J. D. (1979b). Mutants in the biosynthesis of isoleucine in a non-mating, non-sporulating brewing strain of Saccharomyces carlsbergensis. Carlsberg Res. Commun. 44:27–36.

    Article  CAS  Google Scholar 

  • Kielland-Brandt, M. C., Wilken, B., Holmberg, S., Petersen, J. G. L., Nilsson-Tillgren, T. (1980). Genetic evidence for nuclear location of 2-micron DNA in yeast. Carlsberg Res. Commun. 45:119–124.

    Article  CAS  Google Scholar 

  • Kielland-Brandt, M. C., Gjermansen, C., Nilsson-Tillgren, T., Petersen, J. G. L., Holmberg, S., Sigsgaard, P. (1981a). Genetics of a lager production yeast. Tech. Quart. Master Brew. Assoc. Am. 18:185–187.

    CAS  Google Scholar 

  • Kielland-Brandt, M. C., Nilsson-Tillgren, T., Petersen, J. G. L., Holmberg, S. (1981b). Transformation in yeast without the involvement of bacterial plasmids. In: Molecular Genetics in Yeast, edited by D. von Wettstein, J. Friis, M. Kielland-Brandt, A. Stenderup. Copenhagen: Munksgaard, pp. 369–382.

    Google Scholar 

  • Lewis, C. W., Johnston, J. R., Martin, P. A. (1976). The genetics of yeast flocculation. J. Inst. Brew. 82:158–160.

    CAS  Google Scholar 

  • Livingston, D. M. (1977). Inheritance of the 2µm DNA plasmid from Saccharomyces. Genetics 86:73–84.

    PubMed  CAS  Google Scholar 

  • Mortimer, R. K., Schild, D. (1980). Genetic map of Saccharomyces cerevisiae. Microbiol. Rev. 44:519–571.

    PubMed  CAS  Google Scholar 

  • Nilsson-Tillgren, T., Petersen, J. G. L., Holmberg, S., Kielland-Brandt, M. C. (1979). Stabilization by chromosomal integration of HIS4 from an unstable yeast transformant. Meeting on: The Molecular Biology of Yeast. Cold Spring Harbor, N.Y.: Cold Spring Harbor Laboratory, abstract p. 125.

    Google Scholar 

  • Nilsson-Tillgren, T., Petersen, J. G. L., Holmberg, S., Kielland-Brandt, M. C. (1980). Transfer of chromosome III during kar mediated cytoduction in yeast. Carlsberg Res. Commun. 45:113–117.

    Article  Google Scholar 

  • Nilsson-Tillgren, T., Gjermansen, C., Kielland-Brandt, M. C., Petersen, J. G. L., Holmberg, S. (1981). Genetic differences between Saccharomyces carlsbergensis and S. cerevisiae. Analysis by single chromosome transfer. Carlsberg Res. Commun. 46:65–76.

    Article  CAS  Google Scholar 

  • Ramos-Jeunehomme, C., Masschelein, C. A. (1977). Controle genetique de la formation des dicetones vicinales chez Saccharomyces cerevisiae. Eur. Brew. Conv. Congr., Amsterdam, 267–283.

    Google Scholar 

  • Russell, I., Stewart, G. G. (1979). Spheroplast fusion of brewer’s yeast strains. J. Inst. Brew. 85:95–98.

    Google Scholar 

  • Russell, I., Stewart, G. G., Reader, H. P., Johnston, J. R., Martin, P. A. (1980). Revised nomenclature of genes that control yeast flocculation. J. Inst. Brew. 86:120–121.

    Google Scholar 

  • Scherer, S., Davis, R. W. (1979). Replacement of chromosome segments with altered DNA sequences constructed in vitro. Proc. Natl. Acad. Sci. USA 76:4951–4955.

    Article  PubMed  CAS  Google Scholar 

  • Solingen, P. van, Plaat, J. B. van der (1977). Fusion of yeast spheroplasts. J. Bacteriol. 130:946–947.

    PubMed  Google Scholar 

  • Southern, E. M. (1975). Detection of specific sequences among DNA fragments separated by gel electrophoresis. J. Mol. Biol. 98:503–517.

    Article  PubMed  CAS  Google Scholar 

  • Spencer, J. F. T., Spencer, D. M. (1977a). Hybridization of non-sporulating and weakly sporulating strains of brewer’s and distiller’s yeasts. J. Inst. Brew. 83:287–289.

    Google Scholar 

  • Spencer, J. F. T., Spencer, D. M. (1977b). Apparent bisexual behavior of yeast strains obtained from hybridization of industrial yeasts of the genus Saccharomyces with auxotrophic diploids. Antonie van Leeuwenhoek 43:245–254.

    Article  PubMed  CAS  Google Scholar 

  • Stewart, G. G., Russell, I. (1977). The identification, characterization and mapping of a gene for flocculation in Saccharomyces sp. Can. J. Microbiol. 23:441–447.

    Article  PubMed  CAS  Google Scholar 

  • Stewart, G. G., Russell, I. (1979). Current use of the “new” genetics in research and development of brewer’s yeast strains. Eur. Brew. Conv. Congr., Berlin, 475–490.

    Google Scholar 

  • Stewart, G. G., Russell, I., Goring, T. (1975). Nature-nurture anomalies—further studies in yeast flocculation. Am. Soc. Brew. Chem. Proc. 33:137–147.

    Google Scholar 

  • Struhl, K., Stinchcomb, D. T., Scherer, S., Davis, R. W. (1979). High-frequency transformation of yeast: Autonomous replication of hybrid DNA molecules. Proc. Natl. Acad. Sci. USA 76:1035–1039.

    Article  PubMed  CAS  Google Scholar 

  • Tamaki, H. (1978). Genetic studies of ability to ferment starch in Saccharomyces: Gene polymorphism. Mol. Gen. Genet. 164:205–209.

    Article  Google Scholar 

  • Thorne, R. S. W. (1951). The genetics of flocculence in Saccharomyees cerevisiae. Compt. Rend. Lab. Carlsberg, Sér. Physiol. 25:101–140.

    CAS  Google Scholar 

  • Tubb, R. S. (1979). Applying yeast genetics. A current assessment. J. Inst. Brew. 85:286–289.

    Google Scholar 

  • Tubb, R. S. (1980). 2/im DNA plasmid in brewery yeasts. J. Inst. Brew. 86: 78–80.

    CAS  Google Scholar 

  • Wettstein, D. von (1979). Biochemical and molecular genetics in the improvement of malting barley and brewer’s yeast. Eur. Brew. Conv. Congr., Berlin, 587–629.

    Google Scholar 

  • Winge, Ø. (1944). On segregation and mutation in yeast. Compt. Rend. Lab. Carlsberg, Sér. Physiol. 24:79–96.

    Google Scholar 

  • Winge, Ø., Laustsen, O. (1938). Artificial species hybridization in yeast. Compt. Rend. Lab. Carlsberg, Sér. Physiol. 22:235–247.

    Google Scholar 

  • Winge, Ø., Laustsen, O. (1939). On 14 new yeast types, produced by hybridization. Compt. Rend. Lab. Carlsberg, Sér. Physiol. 22:337–355.

    CAS  Google Scholar 

  • Wright, R. E., Lederberg, J. (1957). Extranuclear transmission in yeast heterokaryons. Proc. Natl. Acad. Sci. USA 43:919–923.

    Article  PubMed  CAS  Google Scholar 

  • Young, T. W. (1981). The genetic manipulation of killer character into brewing yeast. J. Inst. Brew. 87:292–295.

    Google Scholar 

  • Zakharov, I. A., Yarovoy, B. Ph. (1977). Cytoduction as a new tool in studying the cytoplasmic heredity in yeast. Mol. Cell. Biochem. 14:15–18.

    Article  PubMed  CAS  Google Scholar 

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Kielland-Brandt, M.C., Nilsson-Tillgren, T., Petersen, J.G.L., Holmberg, S., Gjermansen, C. (1983). Approaches to the Genetic Analysis and Breeding of Brewer’s Yeast. In: Spencer, J.F.T., Spencer, D.M., Smith, A.R.W. (eds) Yeast Genetics. Springer Series in Molecular Biology. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-5491-1_13

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  • DOI: https://doi.org/10.1007/978-1-4612-5491-1_13

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