A New Class of 5α-Reductase Inhibitors

  • G. H. Rasmusson
  • T. Liang
  • J. R. Brooks


Over the past 20 years several approaches to the control of androgen action have been investigated by research teams at Merck & Co., Inc. Basically, these approaches can be described as those that would cause chemical interference at certain critical stages where hormone development or action takes place (Fig. 1). These studies were initiated largely through the efforts of the late Dr. Glen E. Arth, the Steroid Chemistry group leader in the Department of Synthetic Chemical Research (1957–1975).


Androgen Receptor Seminal Vesicle Cyproterone Acetate Ventral Prostate Testosterone Propionate 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag New York Inc. 1983

Authors and Affiliations

  • G. H. Rasmusson
  • T. Liang
  • J. R. Brooks

There are no affiliations available

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