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Cellular Growth and Hormone Receptors

  • Chapter
Benign Prostatic Hypertrophy

Abstract

The hormonal mechanisms related to normal and neoplastic growth of cellular and stromal compartments of the prostate have been the subject of numerous studies, many of which have been based on assessment of circulating levels of steroids and specific steroid-binding proteins in serum over the life span of males of various species, including man.7,18,34,44,48,86,101,102,112 Shifts in hormonal profiles are known to occur in both actual and relative amounts, and as a result some reports have suggested a relationship of such values to normal and diseased conditions of the prostate.36,52,53 Other studies have addressed the metabolism of various hormones that affect the prostate and the mechanisms associated with increased concentrations of dihydrotestosterone in specimens of human benign prostatic hypertrophy (BPH).90,100

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Authors
  1. James P. Karr
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  2. Gerald P. Murphy
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Editors and Affiliations

  1. Department of Urology, University of California, San Francisco, San Francisco, California, 94143, USA

    Frank Hinman Jr. (Clinical Professor of Urology) (Clinical Professor of Urology)

  2. Department of Surgery, Division of Urology, Washington University School of Medicine, St. Louis, Missouri, 63110, USA

    Saul Boyarsky M.D., J.D., F.A.C.S. (Professor of Genitourinary Surgery and Biomedical Engineering) (Professor of Genitourinary Surgery and Biomedical Engineering)

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Karr, J.P., Murphy, G.P. (1983). Cellular Growth and Hormone Receptors. In: Hinman, F., Boyarsky, S. (eds) Benign Prostatic Hypertrophy. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-5476-8_18

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  • DOI: https://doi.org/10.1007/978-1-4612-5476-8_18

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