Disorders of the Area

  • Frederick R. Hine
  • George L. Maddox
  • Redford B. WilliamsJr.
  • Robert C. Carson
  • Redford B. WilliamsJr.

Abstract

It has been emphasized that biobehavioral dispositions—e.g., toward a more schizophrenic way of interacting with the world“cannot be logically considered as the result of either genetic influences or environmental factors. Rather, the point was made that innate and environmental factors act in concert to produce observable patterns of behavior. Furthermore, it was noted that even with the evidence presently available to support the role of heredity in expression of schizophrenic illness, the mechanisms whereby such genetic influences are expressed remain to be elucidated. Also, there are a variety of characteristic psychological functions which have been proposed as basic aspects of the schizophrenic process. At the extreme, these functions are expressed in the full-blown syndrome of a patient with a schizophrenic breakdown. However, it was also noted that these functions may be expressed within the “normal” ranges of human behavior. That is, it is possible to identify, to a less pronounced degree, basic behavioral “tendencies” which, in the individual with schizophrenic disease, are expressed to a more extreme degree.

Keywords

Dementia Histamine Norepinephrine Catecholamine Sorting 

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References

  1. Bleuler, E. Dementia Praecox oder die Gruppe der Schizophrenien. Leipzig: Deuticke, 1911. [Transl. J. Zion. Dementia Praecox or the Group of Schizophrenics. New York, New York: International Universities Press, 1950.]Google Scholar
  2. Buchsbaum, M.S., D.L. Murphy, R.D. Coursey, et al. Platelet monoamine oxidase, plasma dopamine-beta-hydroxylase and attention in a “biochemical high risk” sample. J. Psychiatric Research 14:215–224, 1978.CrossRefGoogle Scholar
  3. Chapman, L.J., and J.P. Chapman. Disordered Thought in Schizophrenia. Englewood Cliffs, New Jersey: Prentice-Hall, 1973.Google Scholar
  4. Creese, I., D.R. Burt, and S.H. Snyder. Dopamine receptor binding predicts clinical and pharmacological potencies of antischizophrenic drugs. Science 192:481, 1976.PubMedCrossRefGoogle Scholar
  5. Corbett, L. Perceptual dyscontrol: A possible organizing principle for schizophrenia research. Schizophrenia Bull. 2:249–265, 1976.Google Scholar
  6. Cromwell, R.L. Assessment of schizophrenia. Ann. Rev. Psychol. 26:593–619, 1975. ia]Diagnostic and Statistical Manual of Mental Disorders, 3rd ed. Washington, D.C.: The American Psychiatric Association, 1980.Google Scholar
  7. Lamprecht, R.B., Eichelman, and N.B. Thoa, et al. Rat fighting behavior: Serum dopamine-beta-hydroxylase and hypothalmic tyrosine hydroxylase. Science 1977:1214, 1972.CrossRefGoogle Scholar
  8. Matthysse, S.W., and K.K. Kidd. Estimating the genetic contributions to schizophrenia. Am. L. Psychiat. 133:185–191, 1976.Google Scholar
  9. Neale, J.M., and R.L. Cromwell. Attention and Schizophrenia. In B.A. Maker (Ed.) Progress in Experimental Personality Research, vol. 5, New York, New York: Academic Press, 1970, pp. 37–66.Google Scholar
  10. Nuechterlein, K.H. Reaction time and attention in schizophrenia: A critical evaluation of the data and theories. Schizophrenia Bull. 3:373–428, 1977.Google Scholar
  11. Oppenheimer, H. Clinical Psychiatry: Issues and Challenges. New York, New York: Harper and Row, 1971.Google Scholar
  12. Pincus, J.H., and G.J. Tucker. Behavioral Neurology, 2nd ed. New York, New York: Oxford University Press, 1978.Google Scholar
  13. Wyatt, R.J., D.L. Murphy, R. Belmaker, et al. Reduced monoamine oxidase activity in platelets: A possible genetic marker for vulnerability to schizophrenia. Science 173:916, 1973.CrossRefGoogle Scholar
  14. Wynn, L.C., R.I. Cromwell, and S. Matthysse (Eds.), The Nature of Schizophrenia: New Approaches to Research and Treatment. New York, New York: Wiley, 1978.Google Scholar
  15. Zubin, T. Problem of attention in schizophrenia. In M.L. Kietzman, A. Sutton, and J. Zubin (Eds.) Experimental Approaches to Psychopathology. New York, New York: Academic Press, 1975, pp. 139–166.Google Scholar

Copyright information

© Springer-Verlag New York Inc. 2004

Authors and Affiliations

  • Frederick R. Hine
    • 1
  • George L. Maddox
    • 2
  • Redford B. WilliamsJr.
    • 1
  • Robert C. Carson
    • 3
  • Redford B. WilliamsJr.
    • 4
    • 5
  1. 1.Duke University Medical CenterDurhamUSA
  2. 2.Center for the Study of Aging and Human DevelopmentDuke University Medical CenterDurhamUSA
  3. 3.Department of PsychologyDuke University Medical CenterDurhamUSA
  4. 4.Department of PsychiatryDuke University Medical CenterDurhamUSA
  5. 5.Department of PediatricsDuke University Medical CenterDurhamUSA

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