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Pathology of Affect: Nuerobiological Aspects

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Introduction to Behavioral Science in Medicine

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Abstract

In Chapter 9 the dopamine theory of schizophrenia was reviewed, along with experimental data showing that genetically and environmentally determined variations in enzyme biosynthesis can influence amine levels and, hence, behavior. We shall now turn our attention to the possible neurochemical bases for disorders of affect and mood, with specific attention being given to the “catecholamine hypothesis” of depression. In addition, we shall consider the CNS mechanisms involved in regulating certain other behaviors which are also disrupted in association with clinical levels of depression.

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Authors and Affiliations

  1. Duke University Medical Center, Durham, North Carolina, 27710, USA

    Frederick R. Hine M.D. (Professor of Psychiatry, Director of Medical Student Education in Psychiatry) & Redford B. Williams Jr. M.D. (Professor of Psychiatry, Associate Professor of Medicine, Lecturer in Psychology)

  2. Center for the Study of Aging and Human Development, Duke University Medical Center, Durham, North Carolina, 27710, USA

    George L. Maddox Ph.D (Professor of Sociology and Medical Sociology (Psychiatry), Director)

  3. Department of Psychology, Duke University Medical Center, Durham, North Carolina, 27710, USA

    Robert C. Carson M.D. (Professor and Chairman)

  4. Department of Psychiatry, Duke University Medical Center, Durham, North Carolina, 27710, USA

    Redford B. Williams Jr. Ph.D. (Associate Professor and Head Division of Medical Psychology)

  5. Department of Pediatrics, Duke University Medical Center, Durham, North Carolina, 27710, USA

    Redford B. Williams Jr. Ph.D. (Associate Professor and Head Division of Medical Psychology)

Authors
  1. Frederick R. Hine M.D.
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  2. George L. Maddox Ph.D
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  3. Redford B. Williams Jr. M.D.
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  4. Robert C. Carson M.D.
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  5. Redford B. Williams Jr. Ph.D.
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© 2004 Springer-Verlag New York Inc.

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Hine, F.R., Maddox, G.L., Williams, R.B., Carson, R.C., Williams, R.B. (2004). Pathology of Affect: Nuerobiological Aspects. In: Introduction to Behavioral Science in Medicine. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-5452-2_14

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  • DOI: https://doi.org/10.1007/978-1-4612-5452-2_14

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-0-387-90736-9

  • Online ISBN: 978-1-4612-5452-2

  • eBook Packages: Springer Book Archive

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