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Cellular Oncogenes and the Pathogenesis of Cancer

  • Robert A. Weinberg

Abstract

Studies in two areas of biology have pointed to the existence of cellular genes that exhibit an oncogenic potential after activation. These normal cellular genes, sometimes termed “proto-oncogenes,” can become activated by several different types of genetic alterations, some involving the intervention of viral genomes. These proto-oncogenes and derived oncogenes represent centrally important components of the molecular mechanisms that create the cancer phenotype.

Keywords

Bladder Carcinoma Cellular Gene Cellular Oncogene Bladder Carcinoma Cell Line Avian Sarcoma Virus 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag New York Inc. 1984

Authors and Affiliations

  • Robert A. Weinberg
    • 1
  1. 1.Whitehead Institute for Biomedical Research and Massachusetts Institute of TechnologyCambridgeUSA

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