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Growth, Cancer, and the Cell Cycle pp 187–201Cite as

Changes in Adhesion, Nuclear Anchorage, and Cytoskeleton During Giant Cell Formation

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Part of the book series: Experimental Biology and Medicine ((EBAM,volume 5))

Abstract

Most cells derived from solid tissues require anchorage to a suitable surface for viability, growth, and the ability to express differentiated functions in culture (1–6). Anchorage becomes altered during growth and differentiation through changes in the contact interactions which a cell makes with other cells, substrata, and soluble extracellular ligands, and in turn influences a wide spectrum of cellular activities, including cell shape, motility, biosynthetic patterns, gene expression, and cell proliferation.

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Authors and Affiliations

  1. Department of Pharmacology/Oncology Research Group, The University of Calgary, Calgary, Alberta, Canada

    Susan Friedman, Catharine Dewar, James Thomas & Philip Skehan

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  1. Susan Friedman
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  2. Catharine Dewar
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  3. James Thomas
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  4. Philip Skehan
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Editor information

Editors and Affiliations

  1. Oncology Research Group and Department of Pharmacology, The University of Calgary, Calgary, Alberta, Canada

    Philip Skehan  & Susan J. Friedman  & 

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© 1984 The Humana Press Inc.

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Friedman, S., Dewar, C., Thomas, J., Skehan, P. (1984). Changes in Adhesion, Nuclear Anchorage, and Cytoskeleton During Giant Cell Formation. In: Skehan, P., Friedman, S.J. (eds) Growth, Cancer, and the Cell Cycle. Experimental Biology and Medicine, vol 5. Humana Press. https://doi.org/10.1007/978-1-4612-5178-1_18

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  • DOI: https://doi.org/10.1007/978-1-4612-5178-1_18

  • Publisher Name: Humana Press

  • Print ISBN: 978-1-4612-9599-0

  • Online ISBN: 978-1-4612-5178-1

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