HLA in Transplantation

  • P. J. Morris
  • S. V. Fuggle
  • I. V. Hutchinson
  • A. Ting
  • K. J. Wood
Part of the Experimental Biology and Medicine book series (EBAM, volume 13)

Abstract

Transplantation is associated with a number of iatrogenic complications and therefore it is perhaps not unreasonable for a discussion on HLA in transplantation to be included in the HLA and Disease Symposium. We propose to discuss some aspects of the current role of matching for HLA in renal transplantation, the increased expression of Class II antigen during rejection episodes in renal transplants, the transfusion effect as observed in man with some experimental data which would provide a role for the MHC in the phenomenon, and finally say something about possible mechanisms of the transfusion effect.

Keywords

Cyclosporin Prednisolone Phosphamide 

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Copyright information

© The Humana Press Inc. 1986

Authors and Affiliations

  • P. J. Morris
    • 1
  • S. V. Fuggle
    • 1
  • I. V. Hutchinson
    • 1
  • A. Ting
    • 1
  • K. J. Wood
    • 1
  1. 1.Nuffield Dept.of SurgeryUniversity of Oxford, John Radcliffe HospitalOxfordUK

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