Phenylethylamine and Personality
The phenylethylamine hypothesis of SABELLI & MOSNAIM (1974) postulates that PEA may play a major role in the modulation of affective behavior. Urinary PEA excretion was determined in 32 drug-free healthy volunteers. The MMPI was used for personality measurement. In the female subgroup a significant positive correlation between PEA and hypomania (rs =.50; p <.05) and a significant negative correlation between PEA and depression (rs = −.65; p <.01) was found supporting this hypothesis. Furthermore, PEA correlated significantly negatively with hypochondriasis (rs = −.58; p <.01), paranoia (rs = −.49; p < 05) and social introversion (rs = −.60; p <.05) These results suggest that PEA excretion may be related to mechanisms responsible for the modulation of affective behavior.
KeywordsEthyl Depression Creatinine Schizophrenia Phenyl
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