Effects of Drugs on Octopamine Metabolism in the Rat

  • David J. Edwards
  • M. L. Sedlock


There is substantial evidence to suggest that octopamine (OCT) is a neurotransmitter in invertebrates, but its role in the neural function of higher organisms is not yet established. Although the presence of OCT in mammalian brain has been demonstrated by a variety of techniques in several laboratories, its presence alone is not sufficient to prove a physiological function.


Tyrosine Hydroxylase Trace Amine Aromatic Amino Acid Decarboxylase Alcoholic Metabolite MHPG Level 
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Copyright information

© The Human Press Inc. 1985

Authors and Affiliations

  • David J. Edwards
    • 1
  • M. L. Sedlock
    • 1
  1. 1.Dept. Pharmacology-PhysiologyUniv. PittsburghPittsburghUSA

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