The Role of Vitamin C in Tumor Therapy (Human)

  • Fukumi Morishige
  • Takahide Nakamura
  • Naoko Nakamura
  • Noritsugu Morishige
Chapter
Part of the Experimental Biology and Medicine, Vol. 10 book series (EBAM, volume 10)

Abstract

About thirty years ago, I started administering large doses of vitamin C to post-operative patients. Its primary aim was to improve the healing of surgical wounds. During that time, I recognized that vitamin C supplemented patients very rarely suffered from post-operative and post-transfused hepatitis. This finding is from observations made on many post-operative patients especially in Kyushu district.

Keywords

Toxicity Hepatitis Lymphoma Adenocarcinoma Sarcoma 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Cameron, E. and Campbell, A. The orthomolecular treatment of cancer II. Clinical trial of high-dose ascorbic acid supplements in advanced human cancer. Chem-Biol. Interactions. 9:285–315, 1974.CrossRefGoogle Scholar
  2. 2.
    Cameron, E. and Pauling, L. Supplemental ascorbate in the supportive treatment of cancer: Prolongation of survival times in terminal human cancer. Proc. Natl. Acad. Sci. 73:3685–3689, 1976.PubMedCrossRefGoogle Scholar
  3. 3.
    Foster, M.A., Pocklington, T., Miller, J.D.B., and Mallard, J.R. A study of electron spin resonance spectra of whole blood from normal and tumor bearing patients. Br. J. Cancer. 28:340–348, 1973.PubMedCrossRefGoogle Scholar
  4. 4.
    Kawasaki, H., Akagi, Y., Nishi, K, Kakuda, T., Kimoto, E., Morishige, F., and Khono, M. Kurume Med. J. 25:273, 1978.CrossRefGoogle Scholar
  5. 5.
    Kawasaki, H., Morishige, F., Tanaka, H., and Kimoto, E. Influence of oral supplementation of ascorbate upon the induction of N-methyl-N’-nitro-N-nitro- soguanidine. Cancer Letters. 16:57–63, 1982.PubMedCrossRefGoogle Scholar
  6. 6.
    Kimoto, E., Tanaka, H., Gyotoku, J., Morishige, F., and Pauling, L. Enhancement of antitumor activity of ascorbate against ehrlich ascites tumor cells by the copper: Glycylglycylhistidine complex. Cancer Res. 43:824–828, 1983.PubMedGoogle Scholar
  7. 7.
    Kirini, Y. and Kwan, Y. Chem. Pharm. Bull. 20:2651, 1972.Google Scholar
  8. 8.
    Lagercrantz, C. Acta Chem. Scand. 18:562, 1964.CrossRefGoogle Scholar
  9. 9.
    Morishige, F. and Murata, A. Intern. Acad. Prevent. Med. 5:47, 1978.Google Scholar
  10. 10.
    Morishige, F., Ohtsu, N., Tanaka, H., Yamaguchi, T., and Kimoto, E. Changes in paramagnetic species of blood plasma following a mega-vitamin C intake. J. Nutri. Growth & Cancer. 1:11–19, 1983.Google Scholar
  11. 11.
    Pocklington, T. and Foster, M.A. Electron spin resonance of caeruloplasmin and iron transferrin in blood of patients with various malignant diseases. Br. J. Cancer. 36:369–374, 1977.PubMedCrossRefGoogle Scholar
  12. 12.
    Sylven, B. and Bois-Svensson, I. On the chemical pathology of interstitial fluid I. Proteolytic activities in transplanted mouse tumors. Cancer Res. 25:458–468, 1965.PubMedGoogle Scholar

Copyright information

© The Humana Press Inc. 1986

Authors and Affiliations

  • Fukumi Morishige
    • 1
  • Takahide Nakamura
    • 1
  • Naoko Nakamura
    • 1
  • Noritsugu Morishige
    • 1
  1. 1.Fukuoka Nakamura Memorial HospitalFukuokaJapan

Personalised recommendations