The Genes of the Murine T Cell Receptor

  • Nicholas R. J. Gascoigne
  • Yueh-hsiu Chien
  • Phillip Patten
  • Daniel M. Becker
  • Tullia Lindsten
  • Joshua Kavaler
  • Nadine E. Lee
  • Mark M. Davis
Chapter
Part of the Experimental Biology and Medicine book series (EBAM, volume 9)

Abstract

T cells recognize antigen in a way fundamentally different from B cells. It has been known now for a decade (1–3) that the T cell receptor sees the antigen, not alone, but in association the major histocompatibility complex (MHC, H-2 in the mouse). As a general rule cytotoxic T (Tc) cells recognize antigen in association with Class I MHC molecules and helper T (Th) cells do so with Class II structures (4,5).

Keywords

Codon Cysteine Proline Lysine Arginine 

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Copyright information

© The Humana Press Inc. 1985

Authors and Affiliations

  • Nicholas R. J. Gascoigne
    • 1
  • Yueh-hsiu Chien
    • 1
  • Phillip Patten
    • 1
  • Daniel M. Becker
    • 1
  • Tullia Lindsten
    • 1
  • Joshua Kavaler
    • 1
  • Nadine E. Lee
    • 1
  • Mark M. Davis
    • 1
  1. 1.Department of Medical Microbiology, Fairchild BuildingStanford University School of MedicineStanfordUSA

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