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Dissociation Constant II: Partial Agonists

  • Ronald J. Tallarida
  • Rodney B. Murray

Abstract

A partial agonist is an agent that requires appreciable receptor occupancy in order to achieve an effect. By way of contrast, full agonists (or strong agonists) have a large spare receptor capacity, that is, these agents produce effects with just a small fraction of their receptors occupied.

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Copyright information

© Springer-Verlag New York Inc. 1987

Authors and Affiliations

  • Ronald J. Tallarida
    • 1
  • Rodney B. Murray
    • 2
  1. 1.Department of PharmacologyTemple University School of MedicinePhiladelphiaUSA
  2. 2.Department of PharmacologyBiosearch Inc.PhiladelphiaUSA

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