Valvular Involvement in Cancer

  • Brent M. Parker


Involvement of the cardiac valves with cancer is relatively infrequent, but clinically important valvular problems may arise. This is most often true with cardiac myxomas, which may cause valvular stenosis or insufficiency, and with nonbacterial thrombotic endocarditis, which may occur as a late complication in patients with malignant neoplasms, especially adenocarcinoma. Valves are resistant to tumor invasion. The paucity of valvular lesions has been attributed to the relative avascularity of these structures. Hence, tumor involvement of the cardiac valves directly is very unusual. A possible scheme of valvular involvement is shown in Table 24.1.


Aortic Valve Mitral Valve Infective Endocarditis Cardiac Valve Bacterial Endocarditis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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© Springer-Verlag New York Inc. 1986

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  • Brent M. Parker

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