Abstract
Recent advances have led to a renewed interest in urinary tract infections in females. First, current research has reassessed the previously used definition of infection as a positive culture with ≥ 100,000 colonies per ml. Norden and Kass1 originally defined a positive culture as ≥ 105 colonies per ml because they found a 96% predictability of a third positive culture if the 2 previous cultures were positive. However, their studies primarily involved pregnant women who were asymptomatic at the time of culture and were not known to be at high risk for recurrent disease. Other authors2,3 reported that symptomatic disease is often associated with colony counts of less than 105 colonies per ml. These studies have thus led to reconsideration of the best way to define infection microbiologically. The roles of new pathogens such as Chlamydia trachomatis, herpes simplex virus (HSV), and Staphylococcus saprophytics have also been demonstrated in recent studies.
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References
Norden W, Kass EH. Bacteriuria of pregnancy-a critical appraisal. Annu Rev Med. 1968;19:431–470.
Stamm WE, Counts GW, Runnin KR, et al. Diagnosis of coliform infection in acutely dysuric women. N Engl J Med. 1982; 307: 463–468.
Gallagher DJA, Montgomerie JZ, North JDK. Acute infections of the urinary tract and the urethral syndrome in general practice. Br Med J. 1965;No. 5435: 622–626.
Thomas V, Shelokov A, Forland M. Antibody coated bacteria in the urine and the site of urinary tract infection. N Engl J Med. 1974; 290: 588–590.
Jones SR, Smith JW, Sanford JP. Localization of urinary tract infections by detection of antibody coated bacteria in urine sediment. N Engl J Med. 1974; 290: 591–593.
Mundt KA, Polk BF. Identification of site of urinary tract infections by antibody coated bacteria assay. Lancet. 1979; 1172–75.
Harris RE, Gilstrap LC III, Pretty A. Single- dose antimicrobial therapy for asymptomatic bacteriuria during pregnancy. Obstet Gynecol. 1982; 59: 546–547.
Waters WE. Prevalence of symptoms of urinary tract infection in women. Br J Prev Soc Med. 1969; 23: 263–266.
Sweet RL. Bacteriuria and pyelonephritis during pregnancy. Semin Perinatol. 1977; 1: 25–40.
Elder HA, Santamarina BAB, Smith S, Kass EH. The natural history of asymptomatic bacteriuria during pregnancy: the effect of tetracycline on the clinical course and the outcome of pregnancy. Am J Obstet Gynecol. 1971; 111: 441–462.
Latham RH, Stamm WE. Urethral syndrome in women. Urol Clin North Am. 1984; 11: 95–101.
Pfau A, Sacks T. The bacterial flora of the vaginal vestibule, urethra and vagina in premenopausal women with recurrent urinary tract infections. J Urol. 1980; 126: 630–634.
Schaeffer AJ, Jones JM, Dunn JK. Association of in vitro E. coli adherance to vaginal and buccal epithelial cells with susceptibility of women to recurrent urinary tract infections. N Engl J Med. 1981; 304: 1062–1066.
Nicolle L, Harding GRM, Preigkatihs J, Ronald AR. The association of urinary tract infection with sexual intercourse. J Infect Dis. 1982; 146: 579–583.
Hughes C, Hacker J, Roberts A, et al. Hemoly-sin production as a virulence marker in symptomatic and asymptomatic urijnary tract infections caused by E. coli. Infect Immun. 1983; 39: 546.
Latham RH, Stamm WE. Role of fimbriated E. coli in urinary tract infections in adult women: correlation with localization studies. J Infect Dis. 1984; 149: 835–839.
Harris RE, Gilstrap LC III. Cystitis during pregnancy: a distinct clinical entity. Obstet Gynecol. 1981; 57: 578–580.
Turck M, Ronald AR, Petersdof RG. Relapse and reinfection in chronic bacteriuria. N Engl J Med. 1968; 278: 422–427.
Leveno KJ, Harris RE, Gilstrap LC III, et al. Bladder versus renal bacteriuria during pregnancy: recurrence after treatment. Am J Obstet Gynecol. 1981; 139: 403–406.
Mabeck CE. Treatment of uncomplicated uri-nary tract infection in nonpregnant women. Postgrad Med J. 1972; 48: 69–75.
Zinner SH, Kass EH. Long-term (10-14 years) follow-up of bacteriuria of pregnancy. N Engl J Med. 1971; 285: 820–824.
Harris RE, Gilstrap LC III. Prevention of recurrent pyelonephritis during pregnancy. Obstet Gynecol. 1974; 44: 637–641.
Whalley PJ, Martin FG, Peters PC. Significance of asymptomatic bacteriuria detected during pregnancy. JAMA. 1965; 193: 107–109.
Stamm WE. Measurement of pyuria and its relationship to bacteriuria. Am J Med. 1983; 75: 53–58.
Lenke RR, vanDorsten JP. The efficacy of the nitrite test and microscopic urinalysis in predicting urine culture results. Am J Obstet Gynecol. 1981; 140: 427–429.
College of American Pathologists. Symposium recommendations, 1984.
Sanford JP. Urinary tract symptoms and infections. Annu Rev Med. 1976; 26: 485–498.
Sheehan G, Harding GKM, Ronald AR. Ad-vances in the treatment of urinary tract infection. Am J Med. 1984; 75: 141–147.
Dodds GH. The immediate and remote progno-sis of pyelitis of pregnancy and the puerperium. J Obstet Gynecol Br Emp. 1932; 39: 47–59.
Lenke RR, vanDorsten JP, Schifrin BS: Pyelonephritis in pregnancy: a prospective randomized trial to prevent recurrent disease evaluating suppressive therapy with nitrofurantoin and close surveillance. Am J Obstet Gynecol. 1983; 146: 953–957.
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© 1986 Springer-Verlag New York, Inc.
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Lenke, R.R., Stamm, W.E. (1986). Urinary Tract Infections. In: Galask, R.P., Larsen, B. (eds) Infectious Diseases in the Female Patient. Clinical Perspectives in Obstetrics and Gynecology. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-4852-1_12
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DOI: https://doi.org/10.1007/978-1-4612-4852-1_12
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