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Bartter’s Syndrome

  • Chapter
Hormone Resistance and Other Endocrine Paradoxes

Part of the book series: Endocrinology and Metabolism ((EAM,volume 1))

Abstract

Our understanding of the pathogenesis of Bartter’s syndrome, although not complete, has evolved greatly since the first description of the disorder in 1962 (1). This chapter reviews the salient features of the syndrome, discussing previous and current concepts of its etiology and treatment, as well as the pathogenesis of the multiple hormonal derangements that accompany Bartter’s syndrome. To illustrate the confusion that can arise concerning the basic definition of Bartter’s syndrome and the essential defects required for proper diagnosis, we begin with clinical summaries of 2 patients with primary renal potassium wasting who demonstrated some but not all of the classic features of Bartter’s syndrome. These cases will be analyzed at the conclusion of the chapter in light of the discourse that follows.

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Authors
  1. Mark D. Okusa
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  2. Margaret Johnson Bia
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Editor information

Editors and Affiliations

  1. University of Medicine and Dentistry of New Jersey, 07103, Newark, New Jersey, USA

    Margo Panush Cohen M.D., Ph.D. (Professor of Medicine, Director) (Professor of Medicine, Director)

  2. Institute for Metabolic Research, University City Science Center, 19104, Philadelphia, Pennsylvania, USA

    Margo Panush Cohen M.D., Ph.D. (Professor of Medicine, Director) (Professor of Medicine, Director)

  3. Wayne State University, USA

    Piero P. Foà M.D., Sc.D. (Professor Emeritus of Physiology, Chairman Emeritus) (Professor Emeritus of Physiology, Chairman Emeritus)

  4. Department of Research, Sinai Hospital, Detroit, Michigan, 48202, USA

    Piero P. Foà M.D., Sc.D. (Professor Emeritus of Physiology, Chairman Emeritus) (Professor Emeritus of Physiology, Chairman Emeritus)

  5. 2104 Rhine Road, 48033, West Bloomfield, Michigan, USA

    Piero P. Foà M.D., Sc.D. (Professor Emeritus of Physiology, Chairman Emeritus) (Professor Emeritus of Physiology, Chairman Emeritus)

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© 1987 Springer-Verlag New York Inc.

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Okusa, M.D., Bia, M.J. (1987). Bartter’s Syndrome. In: Cohen, M.P., Foà, P.P. (eds) Hormone Resistance and Other Endocrine Paradoxes. Endocrinology and Metabolism, vol 1. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-4758-6_8

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  • DOI: https://doi.org/10.1007/978-1-4612-4758-6_8

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4612-9143-5

  • Online ISBN: 978-1-4612-4758-6

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