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Multiple Neurokinin Receptors in the Rat Lower Urinary Tract

  • C. A. Maggi
  • P. Santicioli
  • L. Abelli
  • S. Giuliani
  • M. Furio
  • M. Parlani
  • A. Meli
Conference paper

Abstract

In recent years huge evidence has accumulated indicating that neuropeptides are widely distributed in the lower urinary tract of various animal species(l). The aim of this study was to determine the relative ability of neurokinins (subs tance P, SP; neurokinin A, NKA; neurokinin B, NKB) and tachykinins (kassinin, KASS; eledoisin, ELE; physalaemin, PHYS) to activate motility and produce plasma extravasation in the rat lower urinary tract. The effects of neurokinins (NKs) and tachykinins (TKs) were compared to those of capsaicin, a drug known to stimulate neuropeptide release from primary afferent fibers (2).

Keywords

Calcitonin Gene Related Peptide Evans Blue Rhythmic Contraction Plasma Extravasation Primary Afferent Fiber 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag New York Inc. 1987

Authors and Affiliations

  • C. A. Maggi
    • 1
  • P. Santicioli
    • 1
  • L. Abelli
    • 2
  • S. Giuliani
    • 1
  • M. Furio
    • 2
  • M. Parlani
    • 1
  • A. Meli
    • 1
  1. 1.Pharmacology DepartmentA. Menarini PharmaceuticalsFlorenceItaly
  2. 2.C.R.FRomeItaly

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