Characterization of Binding of [125I]Iodohistidyl1-Substance K to Tachykinin K-Sites in Hamster Bladder
P-type and K-type tachykinin binding sites exist in variable proportions in urinary bladder of different rodent species with hamster bladder containing predominantly high amounts of K-type sites [1; Burcher and Buck, this volume]. In the present report, 125iodohistidyl1-SK (ISK) has been employed as the radioligand to examine in detail the K-sites in hamster bladder.
KeywordsUrinary Bladder Rodent Species Scatchard Analysis Optimal Effect Messenger System
- 1.Burcher, E, Buck, SH (1986) Multiple tachykinin binding sites in hamster, rat, and guinea-pig urinary bladder. Eur. J. Pharmacol., in press.Google Scholar