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Characterization of Binding of [125I]Iodohistidyl1-Substance K to Tachykinin K-Sites in Hamster Bladder

  • S. H. Buck
Conference paper

Abstract

P-type and K-type tachykinin binding sites exist in variable proportions in urinary bladder of different rodent species with hamster bladder containing predominantly high amounts of K-type sites [1; Burcher and Buck, this volume]. In the present report, 125iodohistidyl1-SK (ISK) has been employed as the radioligand to examine in detail the K-sites in hamster bladder.

Keywords

Urinary Bladder Rodent Species Scatchard Analysis Optimal Effect Messenger System 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. 1.
    Burcher, E, Buck, SH (1986) Multiple tachykinin binding sites in hamster, rat, and guinea-pig urinary bladder. Eur. J. Pharmacol., in press.Google Scholar
  2. 2.
    Burcher, E, Buck, SH, Lovenberg, W, O’Donohue, TL (1986) Characterization and autoradiographic localization of multiple tachykinin binding sites in gastrointestinal tract and bladder. J. Pharmacol. Exp. Ther. 236 819–831.PubMedGoogle Scholar

Copyright information

© Springer-Verlag New York Inc. 1987

Authors and Affiliations

  • S. H. Buck
    • 1
  1. 1.Div. Biochemical Sci.Merrell Dow Res. Inst.CincinnatiUSA

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