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Effects of an Amino-Terminal Fragment of Substance P on Brain Dopamine and Serotonin Metabolism

  • M. E. Hall
  • P. DeArmey
  • J. M. Stewart
Conference paper

Abstract

Central or peripheral administration of substance P (SP) produces a number of effects on behavior. In mice, SP decreases isolation-induced aggressive [1] and nociceptive [2] behaviors. SP alters several measures of spontaneous motor behavior in rats and mice [3]. Intraventricular (ICIT) SP dramatically enhances groaning and scratching behavior in mice [4], but not rats [5], while locomotion, sniffing and hindlimb rearing behavior are enhanced in both species [6,7].

Keywords

Substantia Nigra Brain Dopamine HIAA Level Rear Behavior Amine Level 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag New York Inc. 1987

Authors and Affiliations

  • M. E. Hall
    • 1
  • P. DeArmey
    • 1
  • J. M. Stewart
    • 1
  1. 1.Department of BiochemistryUniversity of Colorado School of MedicineDenverUSA

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