Immunocytochemical Localization of Substance P-Like Immunoreactivity in the Human Hypothalamus

  • G. Pelletier
Conference paper

Abstract

Substance P has been found by immunohistochemistry to be largely distributed throughout the central nervous system in several species. This peptide has also been shown to exert some neuroendocrine effects when injected into the brain, such as stimulation of growth hormone and prolactin secretion [1]. In order to obtain more information about the role of substance P in neuroendocrine function in man, we have proceeded to the immunohistochemical localization of this peptide in the human hypothalamus.

Keywords

Morphine Paraffin Prolactin Vale Neurotensin 

References

  1. 1.
    Rivier C, Brown M, Vale W (1977) Effects of neurotensin, substance P and morphine sulfate in the secretion of prolactin and growth hormone in the rat. Endocrinology 100:751–754.PubMedCrossRefGoogle Scholar
  2. 2.
    Sternberger, LA (1972) Immunocytochemistry, Prentice-Hall Inc. Engelwood Cliffs, NJGoogle Scholar

Copyright information

© Springer-Verlag New York Inc. 1987

Authors and Affiliations

  • G. Pelletier
    • 1
  1. 1.MRC Group in Molecular EndocrinologyCentre Hospitalier de l’Université LavalQuebecCanada

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