Immunocytochemical Localization of Substance P-Like Immunoreactivity in the Human Hypothalamus

  • G. Pelletier
Conference paper


Substance P has been found by immunohistochemistry to be largely distributed throughout the central nervous system in several species. This peptide has also been shown to exert some neuroendocrine effects when injected into the brain, such as stimulation of growth hormone and prolactin secretion [1]. In order to obtain more information about the role of substance P in neuroendocrine function in man, we have proceeded to the immunohistochemical localization of this peptide in the human hypothalamus.


Growth Hormone Prolactin Secretion Immunohistochemical Localization Normal Rabbit Serum Pituitary Stalk 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


  1. 1.
    Rivier C, Brown M, Vale W (1977) Effects of neurotensin, substance P and morphine sulfate in the secretion of prolactin and growth hormone in the rat. Endocrinology 100:751–754.PubMedCrossRefGoogle Scholar
  2. 2.
    Sternberger, LA (1972) Immunocytochemistry, Prentice-Hall Inc. Engelwood Cliffs, NJGoogle Scholar

Copyright information

© Springer-Verlag New York Inc. 1987

Authors and Affiliations

  • G. Pelletier
    • 1
  1. 1.MRC Group in Molecular EndocrinologyCentre Hospitalier de l’Université LavalQuebecCanada

Personalised recommendations