Advertisement

Infrequent Phenotypes of Clonogenic Cells in AML: Evidence for Abnormal Differentiation and Possibilities for Detecting Minimal Disease?

  • Bob Löwenberg
  • Ruud Delwel
Chapter
Part of the Experimental Biology and Medicine book series (EBAM, volume 17)

Abstract

Efforts to detect minimal numbers of AML clonogenic cells (AML-CFU) in the marrow during complete remission depend on phenotypic properties which distinguish AML-CFU from normal marrow stem and progenitor cells.

Keywords

Fluorescence Activate Cell Sorting Clonogenic Cell Normal Marrow Normal Bone Marrow Cell Discriminative Marker 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Lange, B., Ferrero, D., Pessano, S., Palumbo, A., Faust, J., Meo, P., Rovera, G. (1984) Blood 64, 693.PubMedGoogle Scholar
  2. 2.
    Sabbath, K.D., Ball, E.D., Larcom, P., Davis, R.B., Griffin, J.D. (1985) J.Clin.Invest. 75, 746.PubMedCrossRefGoogle Scholar
  3. 3.
    Löwenberg, B., Bauman, J.G.J. (1985) Blood 66, 1225.PubMedGoogle Scholar
  4. 4.
    Wouters, R., Löwenberg, B. (1984) Blood 63, 684.PubMedGoogle Scholar
  5. 5.
    Touw, I.P., Löwenberg, B. (1985) Brit.J.Haemat. 59, 37.PubMedCrossRefGoogle Scholar
  6. 6.
    Löwenberg, B., Swart, K., Hagemeijer, A. (1980) Leuk.Res. 4, 143.PubMedCrossRefGoogle Scholar
  7. 7.
    Löwenberg, B., Hagemeijer, A., Swart, K. (1982) Blood 59, 641.PubMedGoogle Scholar
  8. 8.
    Swart, K., Hagemeijer, A., Löwenberg, B. (1982) Blood 59, 816.PubMedGoogle Scholar
  9. 9.
    Deiwel, H.R., Touw, I.P., Löwenberg, B. (1985) Blood 68, 41.Google Scholar
  10. 10.
    Majdic, O., Bettelheim, P., Stockinger, H., Aberer, W., Liszka, K., Lutz, D. and Knapp, W. (1984) Int.J. Cancer 33, 617.PubMedCrossRefGoogle Scholar
  11. 11.
    Civin, C.I., Strauss, L.C., Brovall, C., Fackler, M.J., Schwartz, J.F., Shaper, J.H. (1984) J.Immunol. 133, 157.PubMedGoogle Scholar
  12. 12.
    Bodger, M.P., Francis, G.E., Delia, D., Granger, S.M. and Janossy, G. (1981) J.Immunol. 127, 2269.PubMedGoogle Scholar
  13. 13.
    Delwel, R., Bot, F., Touw, I.P. and Löwenberg, B. Exceptional phenotypes of progenitors in acute myelocytic leukemia (AML-CFU): possibilities for separating AML-CFU from normal marrow progenitors. (1986) Blood submitted.Google Scholar
  14. 14.
    Griffin, J.D. and Löwenberg, B. (1986) Blood in press.Google Scholar

Copyright information

© The Humana Press Inc. 1987

Authors and Affiliations

  • Bob Löwenberg
    • 1
  • Ruud Delwel
    • 1
  1. 1.The Dr Daniel den Hoed Cancer CenterRotterdamThe Netherlands

Personalised recommendations