Abstract
The notion that aberrant cell differentiation is a consistent and important characteristic of malignant cells has been a popular theme in cancer research for many years. Theories concerning phenomena such as dedifferentiation, misprogramming of differentiated lineages, and inappropriate or ectopic expression of genes associated with embryonic development have often been linked to the progression of malignancy (1,2).
Keywords
- Nude Athymic Mouse
- Tumorigenic Phenotype
- Restriction Fragment Length Polymorphism Probe
- Parental HeLa
- Human Foreskin Keratinocytes
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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Stanbridge, E.J. (1987). Differentiation as a Mechanism for Control of Malignancy in Human Cell Hybrids. In: Aarbakke, J., Chiang, P.K., Koeffler, H.P. (eds) Tumor Cell Differentiation. Experimental Biology and Medicine, vol 17. Humana Press. https://doi.org/10.1007/978-1-4612-4594-0_22
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DOI: https://doi.org/10.1007/978-1-4612-4594-0_22
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