Inhibition of Interleukin-2 Synthesis by Infectious Mononucleosis-Associated IgG Blocking Factor
Sera from patients with Epstein-Barr virus (EBV)-induced infectious mononucleosis (IM) contain an IgG-blocking factor (IM-IgG) which inhibits cell-mediated immunity. Here we summarize evidence showing that the immunosuppressive effects of IM-IgG result from its inhibitory effect on interleukin-2 production.
KeywordsNatural Killer Natural Killer Cell Nasopharyngeal Carcinoma Infectious Mononucleosis Natural Killer Activity
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