Morbidity of Epstein-Barr Virus Infection in Children
Primary infections with the Epstein-Barr virus (EBV) commonly occur in childhood. However, the classical combination of fever, pharyngitis, adenopathy and splenomegaly which is characteristic of infectious mononucleosis in adolescents and young adults is rare in children. On occasion complications of EBV infection may be the only presenting manifestations of EBV disease in children (1). We have retrospectively reviewed the case records of 41 children with EBV disease referred either to a university pediatric department or to a children’s oncology center for presumed malignancy. Our findings suggest that EBV may cause prolonged illness, and, in addition, may lead to serious, potentially life threatening complications.
KeywordsInfectious Mononucleosis Viral Meningitis Atypical Lymphocyte Prolonged Illness Potential Life Threatening Complication
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