Endothelium-Dependent Responses in Large Arteries and in the Microcirculation
Studies focusing on specific components of the blood vessel wall have yielded an important secret of how the “microenvironment” can control large and small artery diameter. As a result of the now classic discovery of endothelium-derived relaxing factor (EDRF) by Furchgott and Zawad-zki (1980), any discussion of the physiology or pathology of vascular reactivity must consider the integrity and function of the cells lining the intimal surface.
KeywordsCholesterol Adenosine Cardiol Acetylcholine Propranolol
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