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Accelerated Recovery of Hematopoiesis with Radioprotective Cu-DIPS

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Biology of Copper Complexes

Part of the book series: Experimental Biology and Medicine ((EBAM,volume 16))

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Abstract

Copper (II) (3, 5-diisopropylsali cylate)2 (Cu-DIPS), administered to mice 3 hr prior to exposure to 8.0 Gy irradiation, increased the 42 day survival rate from 40% to 85%. Treatment with Cu-DIPS significantly accelerated spleen repopulation and the recovery of immune responsiveness following irradiation.2 In the present study the effects of Cu-DIPS on the recovery of hematopoietic activity in bone marrow and spleen following irradiation were investigated.

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References

  1. Salari, H., Baker, M. L., Barnett, J. B., Soderberg, L. S. F., Willingham, W. M. and Sorenson, J. R. J. In: Biology of Copper Complexes; Ed. J. Sorenson; Humana Press, NJ, in press, (this proceedings)

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  2. Soderberg, L. S. F., Barnett, J. B., Baker, M. L., Salari, H., and Sorenson, J. R. J. In: Biology of Copper Complexes; Ed. J. Sorenson; Humana Press, NJ, in press. (this proceedings)

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  3. Nicola, N. A., Burgess, A. W., Metcalf, D. J. Biol. Chem. 1979. 254, 5290.

    CAS  Google Scholar 

  4. Nicola, N. A., and Metcalf, D. J. Cell. Physiol. 1981, 109, 253.

    Article  CAS  Google Scholar 

  5. Hopel, A. J., Fung, M. C, Johnson, R. M., Young, I. G., Johnson, G., and Metcalf, D. Blood 1985, 65, 1453.

    Google Scholar 

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© 1987 The Humana Press Inc.

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Soderberg, L.S.F., Barnett, J.B., Baker, M.L., Salari, H., Sorenson, J.R.J. (1987). Accelerated Recovery of Hematopoiesis with Radioprotective Cu-DIPS. In: Sorenson, J.R.J. (eds) Biology of Copper Complexes. Experimental Biology and Medicine, vol 16. Humana Press. https://doi.org/10.1007/978-1-4612-4584-1_45

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  • DOI: https://doi.org/10.1007/978-1-4612-4584-1_45

  • Publisher Name: Humana Press

  • Print ISBN: 978-1-4612-8937-1

  • Online ISBN: 978-1-4612-4584-1

  • eBook Packages: Springer Book Archive

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