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Modulation of Lymphocyte Function by Copper and Thiols

  • Peter E. Lipsky
Part of the Experimental Biology and Medicine book series (EBAM, volume 16)

Abstract

D-Penicillamine is effective in the treatment of rheumatoid arthritis. Moreover, D-penicillamine can modify the disease process as evidenced by the capacity to decrease acute phase reactants1. Despite this well-documented evidence of clinical efficacy, the mechanism by which D-penicillamine achieves this therapeutic result in rheumatoid arthritis remains unknown.

Keywords

Rheumatoid Arthritis Angiotensin Converting Enzyme Inhibitor Lymphocyte Function Natural Killer Cell Function Free Sulfhydryl Group 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© The Humana Press Inc. 1987

Authors and Affiliations

  • Peter E. Lipsky
    • 1
    • 2
  1. 1.Harold C. Simmons Arthritis Research CenterDallasUSA
  2. 2.Department of Internal MedicineUTHSCD Southwestern Medical SchoolDallasUSA

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