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Hypersensitivity Lung Disease and Challenge Testing

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Legal Aspects of Medicine

Abstract

Hypersensitivity pneumonitis (HP) or extrinsic allergic alveolitis (British terminology) is defined as a pulmonary illness caused by an immunologic reaction to a variety of inhaled environmental antigens that involves the periphery of the lung.1 The affected subject acquires an abnormal sensitivity or heightened reactivity to the inciting agent, resulting in an inflammatory host response located primarily in the alveolar-air exchange portion of the lung rather than in the conducting airways seen in asthma. The distinction is important, for certain types of asthma, notably extrinsic, IgE-mediated allergic asthma, is also a form of hypersensitivity lung disease often associated with airborne organic antigens.2

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References

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© 1989 Springer-Verlag New York Inc.

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Schlueter, D.P., Mathai, G., Klein, D. (1989). Hypersensitivity Lung Disease and Challenge Testing. In: Vevaina, J.R., Bone, R.C., Kassoff, E. (eds) Legal Aspects of Medicine. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-4534-6_30

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  • DOI: https://doi.org/10.1007/978-1-4612-4534-6_30

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4612-8867-1

  • Online ISBN: 978-1-4612-4534-6

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