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Kinetics of Anion Transport

  • Chapter
The Red Cell Membrane

Part of the book series: Contemporary Biomedicine ((CB,volume 10))

Abstract

This chapter will deal primarily with the question of what we can learn about the red-cell anion transport system from kinetic studies, that is, measurements of ion fluxes under different conditions and in the presence of various inhibitors. It is important to recognize, however, that one of the chief advantages of the red-cell anion transport system has been the availability of structural data on the transport protein as well as kinetic data. Largely for reasons of brevity, this chapter will focus on only a few subjects that, in my opinion, will be important in linking the kinetic information with structural studies (see Chapter 8) to develop a molecular model for the transport process. For a broader overview of the kinetics of transport, the reader is referred to several comprehensive reviews (Macara and Cantley, 1983; Knauf, 1979, 1986; Passow, 1986; Fröhlich and Gunn, 1986).

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Authors
  1. Philip A. Knauf
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Editors and Affiliations

  1. Department of Pharmacology and Toxicology, Indiana University School of Medicine, Evansville, Indiana, USA

    B. U. Raess

  2. Department of Biochemistry, Indiana University School of Medicine, Evansville, Indiana, USA

    Godfrey Tunnicliff

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Knauf, P.A. (1989). Kinetics of Anion Transport. In: Raess, B.U., Tunnicliff, G. (eds) The Red Cell Membrane. Contemporary Biomedicine, vol 10. Humana Press. https://doi.org/10.1007/978-1-4612-4500-1_9

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  • DOI: https://doi.org/10.1007/978-1-4612-4500-1_9

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