Need and Applications of Integrated Red Cell Models
The behavior of a cell within a tissue, organ, or organism is the result of direct or indirect interactions among diverse, functional molecular units. The methodological advances of the last few decades have provided much information on the identity and function of a large variety of cell components, and on the chemical structure and operation of isolated, purified, or reconstituted molecular entities. If the understanding of a cell, organ, and organismal physiology is ever to be derived from the integration of elemental functions into progressively higher order mathematical representations, a general approach to integrated modeling must first be explored.
KeywordsSickle Cell Anemia Human Erythrocyte Diffusible Anion Anion Permeability Cell Dehydration
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