Skip to main content
SpringerLink
Log in

Current Concepts in the Treatment of Cancer of the Prostate

  • Chapter
Hormones and Cancer

Part of the book series: Hormones in Health and Disease ((HHD))

Abstract

Carcinoma of the prostate is the most common cancer in men in the United States and the second most common cause of cancer death. In addition, both these figures are increasing at an alarming rate. The incidence of prostate cancer goes up with advancing age but the disease is being recognized increasingly in younger men.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 129.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 169.00
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Bagshaw MA, Cox RS, Rambach JE (1990): Radiation therapy for localized prostate cancer. Urol Clin N Am 17: 787–802

    CAS  Google Scholar 

  • Carter BS, Bova GS, Beaty TH, Steinberg GD, Childs B, Isaacs WB, Walsh PC (1993): Hereditary prostate cancer: epidemiologic and clinical features. J Urol 150 (3): 797–802

    PubMed  CAS  Google Scholar 

  • Catalona WJ, Smith DS, Ratliff TL, Dodds KM, Coplen DE, Yuan JJ, Petros JA, Andriole GL (1991): Measurement of prostate specific antigen in serum as a screening test for prostate cancer. N Engl J Med 324: 1156–1161

    Article  PubMed  CAS  Google Scholar 

  • Catalona WJ, Richie JP, Ahmann FR, Hudson MA, Scardino PT, Flanigan RC, deKernion JB, Ratliff TL, Kavoussi LR, Dalkin BL, Waters WB, MacFarlane MT, Southwick PC (1994): Comparison of digital rectal examination and serum prostate specific antigen in the early detection of prostate cancer: results of a multicenter clinical rial of 6630 men. J Urol 151 (5): 1283–1290

    PubMed  CAS  Google Scholar 

  • Chodak GW, Keller P, Schoenberg HW (1989): Assessment of screening for prostate cancer using the digital rectal examination. J Urol 141 (5): 1136–1138

    PubMed  CAS  Google Scholar 

  • Chodak GW, Thisted RA, Gerber GS, Johansson JE, Adolfsson J, Jones GW, Chisholm DD, Moskovitz B, Livne PM, Warner J (1994): Results of conservative management of clinically localized prostate cancer. N Engl J Med 330: 242–248

    Article  PubMed  CAS  Google Scholar 

  • Cooner WH, Mosley BR, Rutherford CL, Beard JH, Pond HS, Terry WJ, Igel TC, Kidd DD (1990): Prostate cancer detection in a clinical urological practice by ultrasonography, digital rectal examination and prostate specific antigen. J Urol 143(6):1146–1152; discussion 1152–1154

    Google Scholar 

  • Crawford ED, Eisenbergen MA, McLeod DG, Spaulding JT, Benson R, Dorr FA (1989): A controlled trial of leuprolide with and without flutamide in prostatic carcinoma. N Engl J Med 321: 419–424

    Article  PubMed  CAS  Google Scholar 

  • Eisenberger MA, Bezerdigan L, Kalash S (1987): A critical assessment of the role of chemotherapy for endocrine resistant prostatic carcinoma. Urol Clin N Am 14: 695–706

    CAS  Google Scholar 

  • Epstein JI, Walsh PC, Carmichael M, Brendler CB (1994): Pathologic and clinical findings to predict tumor extent of nonpalpable (stage Tic) prostate cancer. JAMA 271 (5): 368–374

    Article  PubMed  CAS  Google Scholar 

  • Garmick MB, Glode LM, Smith JA Jr (1985): Leuprolide versus diethylstilbestrol for metastatic prostate cancer. N Engl J Med 311: 1281–1286

    Google Scholar 

  • Hanks GE, Asbell S, Krall JM, Perez CA, Doggett S, Robin P, Sause W, Pilepich MV (1991): Outcome for lymph node dissection negative Tib, T2 prostate cancer treated with external beam radiation therapy in RTOG 77-06. Int J Rad Oncol Biol Physiol 21: 1009–1103

    Google Scholar 

  • Hernandez AD, Smith JA Jr (1990): Transrectal ultrasonography for the early detection and staging of prostate cancer. Urol Clin N Am 17: 745–757

    CAS  Google Scholar 

  • Huggins C, Hodges CV (1941): Studies on prostatic cancer. I. The effect of castration, estrogen and androgen injections or serum phosphatases in metastatic carcinoma of the prostate. Cancer Res 1: 293–295

    CAS  Google Scholar 

  • Johansson JE, Adami HO, Andersson SO, Bergstrom R, Holmberg L, Krusemo UB (1992): High 10 year survival rate in patients with early untreated prostate cancer. JAMA 267: 2191–2196

    Article  PubMed  CAS  Google Scholar 

  • Koch MO, Smith J A, Hodge EM, Brandell RA (1994): Prospective development of a cost efficient program for radical retropubic prostatectomy. Urology 44 (3): 311–318

    Article  PubMed  CAS  Google Scholar 

  • Labrie F (1991): Endocrine therapy of prostate cancer. Endocrinol Metab Clin N Am 20: 845–872

    CAS  Google Scholar 

  • Laing AH, Ackery DM, Bayly RJ, Buchanan RB, Lewington VJ, McEwan AJ, Macleod PM, Zivanovic MA (1991): Strontium-89 chloride for pain palliation in prostatic skeletal malignancy. Br J Radiol 64: 816–822

    Article  PubMed  CAS  Google Scholar 

  • LaRocca RV, Cooper MR, Uhrich M, Danesi R, Walther MM, Linehan WM, Myers CE (1991): Use of suramin in treatment of prostatic carcinoma refractory to conventional hormonal manipulation. Urol Clin N Am 18: 123–129

    Google Scholar 

  • Lee F, Littrup PJ, Torp-Pedersen ST, Mettlin C, McHugh TA, Gray JM, Kumasaka GH, McLeary RD (1988): Prostate cancer: comparison of transrectal US and digital rectal examination for screening. Radiology 168 (2): 389–394

    PubMed  CAS  Google Scholar 

  • Lewington VJ, McEwan AJ, Ackery DM, Bayly RJ, Keeling DH, Macleod PM, Porter AT, Zivanovic MA (1991): A prospective, randomized double-blind crossover study to examine the efficacy of strontium-89 in pain palliation in patients with advanced prostate cancer metastatic to bone. Eur J Cancer 27: 954–958

    Article  PubMed  CAS  Google Scholar 

  • McWhorter WP, Hernandez AD, Meikle AW, Terreros DA, Smith JA Jr, Skolnick MH, Cannon-Albright LA, Eyre HJ (1992): A screening study of prostate cancer in high risk families. J Urol 148: 826–828

    PubMed  CAS  Google Scholar 

  • Mettlin C, Lee F, Drago J, Murphy GP (1991): The American Cancer Society National Prostate Cancer Detection Project. Findings on the detection of early prostate cancer in 2425 men. Cancer 67 (12): 2949–2958

    Article  PubMed  CAS  Google Scholar 

  • Middleton RG, Larsen RH (1990): Selection of patients with stage B prostate cancer for radical prostatectomy. Urol Clin N Am 17: 779–786

    CAS  Google Scholar 

  • Oesterling JE (1991): Prostate specific antigen: A critical assessment of the most useful tumor marker for prostate cancer. J Urol 145: 907–923

    PubMed  CAS  Google Scholar 

  • Oesterling JE, Cooner WH, Jacobsen SJ, Guess HA, Lieber MM (1993): Influence of patient age on the serum PSA concentration. An important clinical observation. Urol Clin N Am 20 (4): 671–680

    CAS  Google Scholar 

  • Rosen MA, Goldstone L, Lapin S, Wheeler T, Scardino PT (1992): Frequency and location of extracapsular extension and positive surgical margins in radical prostatectomy specimens. J Urol 148: 331–337

    PubMed  CAS  Google Scholar 

  • Scaletscky R, Koch MO, Eckstein CW, Bicknell SL, Gray GF Jr, Smith JA Jr (1994): Tumor volume and stage in carcinoma of the prostate detected by elevation in prostate specific antigen. J Urol 152: 129–131

    PubMed  CAS  Google Scholar 

  • Schellhammer PF, Whitmore RB, Kuban DA, El-Mahdi AM, Ladaga LA (1989): Morbidity and mortality of local failure after definitive therapy for prostate cancer. J Urol 141: 567 - 571

    PubMed  CAS  Google Scholar 

  • Seidman AD, Scher HI, Petrylak D, Dershaw DD, Curley T (1992): Estramustine and vinblastine: use of prostate specific antigen as a clinical trial endpoint in hormone-refractory prostatic cancer. J Urol 147: 931–934

    PubMed  CAS  Google Scholar 

  • Shinohara K, Wheeler TM, Scardino PT (1989): The appearance of prostate cancer on transrectal ultrasonography: correlation of imaging and pathological examinations. J Urol 142 (l): 76–82

    PubMed  CAS  Google Scholar 

  • Smith JA Jr (1984): Androgen suppression by a gonadotropin releasing hormone analog in patients with metastatic carcinoma of the prostate. J Urol 131: 1110–1112

    PubMed  Google Scholar 

  • Smith JA Jr (1987): Endocrine treatment. In: Clinical Management of Prostate Cancer. Smith JA Jr, Middleton RG (eds). Chicago: Year Book Medical Publishers, pp 134–153

    Google Scholar 

  • Smith JA Jr (1994): A prospective comparison of treatments for symptomatic hot flushes following endocrine therapy for carcinoma of the prostate. J Urol 152: 132 - 134.

    PubMed  Google Scholar 

  • Tannock I, Gospodarowicz M, Meakin W, Panzarella T, Stewart L, Rider W (1989): Treatment of metastatic prostatic cancer with low-dose prednisone: evaluation of pain and quality of life as pragmatic indices of response. J Clin Oncol 7: 590–597

    PubMed  CAS  Google Scholar 

  • Terris MK, McNeal JE, Stamey TA (1992): Detection of clinically significant prostate cancer by transrectal ultrasound-guided systematic biopsies. J Urol 148 (3): 829–832

    PubMed  CAS  Google Scholar 

  • Walsh PE, Epstein JI, Lowe FC (1987): Potency following radical prostatectomy with wide unilateral excision of the neurovascular bundle. J Urol 138: 823–827

    PubMed  CAS  Google Scholar 

  • Wheeler J A, Zagars GK, Ayala AG (1993): Dedifferentiation of locally recurrent prostate cancer after radiation therapy. Evidence for tumorprogression. Cancer 71: 3783–3787

    Article  PubMed  CAS  Google Scholar 

  • Whitmore WF Jr, Warner JA, Thompson IM Jr (1991): Expectant management of localized prostate cancer. Cancer 67: 1091–1096

    Article  PubMed  Google Scholar 

  • Yagoda A, Smith JA Jr, Soloway MS, Tomera K, Seidmon EJ, Olsson C, Wajsman Z (1991): Phase II study of estramustine phosphate in advanced hormone refractory prostatic cancer with increasing prostate specific antigen levels. J Urol 145: 384A

    Google Scholar 

Download references

Authors
  1. Joseph A. Smith Jr.
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Department of Biochemistry and Molecular Biology, Louisiana State University Medical Center, 1901 Perdido Street, 70112-1393, New Orleans, LA, USA

    Wayne V. Vedeckis

  2. Stanley S. Scott Cancer Center, 1901 Perdido Street, 70112-1393, New Orleans, LA, USA

    Wayne V. Vedeckis

Rights and permissions

Reprints and permissions

Copyright information

© 1996 Birkhäuser Boston

About this chapter

Cite this chapter

Smith, J.A. (1996). Current Concepts in the Treatment of Cancer of the Prostate. In: Vedeckis, W.V. (eds) Hormones and Cancer. Hormones in Health and Disease. Birkhäuser Boston. https://doi.org/10.1007/978-1-4612-4266-6_13

Download citation

  • DOI: https://doi.org/10.1007/978-1-4612-4266-6_13

  • Publisher Name: Birkhäuser Boston

  • Print ISBN: 978-1-4612-8715-5

  • Online ISBN: 978-1-4612-4266-6

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation