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Diabetes and Dementia: A Retrospective Neuropathologic Study of Old Diabetics Compared to Non-Diabetic Controls

  • Jean-Pierre Michel
  • Pius Muller
  • Gabriel Gold
  • Willliam Mac Gee
  • Reihnild Mulligan
  • Constantin Bouras
Part of the Advances in Alzheimer Disease Therapy book series (AADT)

Abstract

Non-insulin-dependent diabetes mellitus (NIDDM) and dementia are both characterized by high prevalence in later life (Muller, 1993). Differences in prevalence of NIDDM according to regions and races are well-known. In an industrialized society, with a predominantly white population, the rate of NIDDM increases linearly starting from 35 years old, reaching 15% at the age of 75 (Wilson et al., 1986) and 20% at the age of 80 (Morley and Perry, 1991). As for Alzheimer’s Disease (AD), it follows an exponential curve starting from the age of 50, reaching 30% for the 85 year-old population (Skoog et al., 1993).

Keywords

Vascular Dementia Cerebral Amyloid Angiopathy Alzheimer Type Microscopic Lesion Elderly Diabetic 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Birkhäuser Boston 1997

Authors and Affiliations

  • Jean-Pierre Michel
    • 1
  • Pius Muller
    • 1
  • Gabriel Gold
    • 1
  • Willliam Mac Gee
    • 1
  • Reihnild Mulligan
    • 1
  • Constantin Bouras
    • 2
  1. 1.Department of GeriatricsUniversity Hospitals of GenevaThônex-GenevaSwitzerland
  2. 2.Neuropathology Division, Department of PsychiatryUniversity Hospitals of GenevaThônex-GenevaSwitzerland

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