A New Focus on Cytoskeletal Therapy in Alzheimer’s Disease
The classical approach to Alzheimer’s Disease (AD) starts from the neuropathological findings and assumes any reasonable model should at least incorporate either β-amyloid plaques or neurofibrillary tangles. However, these neuropathological features are just tombstones of a disease process going on for several years. In the absence of specific and sensitive imaging markers for these aberrant protein forms, we will not be able to judge properly on their relevance to the course of the pathology per se.
KeywordsNerve Growth Factor Axonal Transport Okadaic Acid Sodium Butyrate Fast Axonal Transport
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