A New Focus on Cytoskeletal Therapy in Alzheimer’s Disease

  • Hugo Geerts
  • Rony Nuydens
  • Mirjam de Jong
  • Gerd van de Kieboom
Part of the Advances in Alzheimer Disease Therapy book series (AADT)

Abstract

The classical approach to Alzheimer’s Disease (AD) starts from the neuropathological findings and assumes any reasonable model should at least incorporate either β-amyloid plaques or neurofibrillary tangles. However, these neuropathological features are just tombstones of a disease process going on for several years. In the absence of specific and sensitive imaging markers for these aberrant protein forms, we will not be able to judge properly on their relevance to the course of the pathology per se.

Keywords

Serotonin Neurol Tryptophan Neuroblastoma Butyrate 

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Copyright information

© Birkhäuser Boston 1997

Authors and Affiliations

  • Hugo Geerts
    • 1
  • Rony Nuydens
    • 1
  • Mirjam de Jong
    • 1
  • Gerd van de Kieboom
    • 1
  1. 1.Dept Cellular PhysiologyJanssen Research FoundationBeerseBelgium

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