Criteria for the Clinical Diagnosis of Alzheimer’s Disease: Transcultural Aspects

  • Luigi Amaducci
  • Marzia Baldereschi
Part of the Advances in Alzheimer Disease Therapy book series (AADT)


The clinical diagnosis of Alzheimer’s Disease (AD) is now usually based on the use of structured diagnostic criteria. Although that is an essential step in the standardization of AD clinical diagnosis, differences in the observation and interpretation of findings may affect the reliability of the diagnostic instrument.


Depression Dementia Nigeria Poss 


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  1. Anthony JC, Le Resche L and Niaz U (1982): Limits of the Mini-Mental-State as a screening test for dementia and delirium among hospital patients. Psychol Med 12:397–408.PubMedCrossRefGoogle Scholar
  2. Baldereschi M, Meneghini F, Quiroga P, Albala C, Mamo J, Muscat P, Gabriel R, Bermejo F, Amaducci L and Katzman R (1994a): Cognitive versus functional screening for dementia across different countries: cross-cultural validation of the Mini-Mental-State Examination (MMSE) and of the Pfeffer Functional Activities Questionnaire (PFAQ) against the standardized clinical diagnosis of dementia. Neurology 44 (suppl. 2):A365.Google Scholar
  3. Baldereschi M, Amato MP, Nencini P, Pracucci G, Lippi A, Amaducci L, Gauthier S, Beatty L, Quiroga P, Klassen G, Galea A and Muscat P, Osuntokun B, Ogunniyi A, Portera-Sanchez A, Bermejo F, Hendrie H, Burdine V, Brashear A, Farlow M, Maggi S, Katzman R (1994b): Cross-national interrater agreement on the clinical diagnostic criteria for dementia. Neurology 44:239–242.PubMedGoogle Scholar
  4. Baldereschi M, Grigoletto F, Mamo J, Muscat P, Gabriel R, Bermejo F, Quiroga P, Albala C, Amaducci L and Katzman R (1995): Cross-cultural validation of a modified version of the Mini-Mental-State Examination and of a serial testing procedure. Neurology 45 (suppl. 4):A326.Google Scholar
  5. Bird HR, Canino G and Stipec MR (1987): Use of the Mini-Mental-State Examination in a probability sample of an hispanic population. J New Ment Dis 175:731–737.CrossRefGoogle Scholar
  6. Escobar JI, Burnam A and Karho M (1986): Use of the Mini-Mental-State Examination (MMSE) in a community population of mixed ethnicity. Cultural and linguistic artifacts. J New Ment Dis 174:607–614.CrossRefGoogle Scholar
  7. Folstein M, Anthony JC and Parhad I (1985): The meaning of cognitive impairment in the elderly. J Am Geriatr Soc 33:228–235.PubMedGoogle Scholar
  8. Folstein MF, Folstein SE and McHugh PR (1975): Mini-Mental-State: a practical method for grading the cognitive state of patients for the clinicians. J Psychiatr Res 12:189–198.PubMedCrossRefGoogle Scholar
  9. Jin H, Zhang HY and Qu Oy (1989): Cross-cultural studies on dementia: use of a Chinese version of the Blessed-Roth Information-Memory-Concentration test in a Shangai dementia survey. Psychol Aging 4:471–479PubMedCrossRefGoogle Scholar
  10. Lopez OL, Swihart AA, Becker JT, Reinmuth OM, Reynolds III CF, Rezek DL and Daly FL (1990): Reliability of NINCDS-ADRDA clinical criteria for the diagnosis of Alzheimer’s disease. Neurology 40:1517–1522.PubMedGoogle Scholar
  11. Pfeffer R, Kurosaki TT, Harrah CH, Chance JM and Filos S, (1982): Measurement of functional activities in older adults in the community. J Gerontol 37:323–329.PubMedGoogle Scholar

Copyright information

© Birkhäuser Boston 1997

Authors and Affiliations

  • Luigi Amaducci
    • 1
  • Marzia Baldereschi
    • 2
  1. 1.Department of NeurologyUniversity of FlorenceFlorenceItaly
  2. 2.Targeted Project on AgingNational Research Council of ItalyFlorenceItaly

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