Skip to main content
SpringerLink
Log in

Viral-Chemical Combination Effects in Tumorigenesis

  • Chapter
Chemical Induction of Cancer

  • 98 Accesses

Abstract

Shortly after the discovery of the first tumor virus by Rous (1) in 1911 and the first experimental demonstration of chemical induction of cancer in rabbit skin by painting coal tar by Yamagiwa and Ichikawa (2) in 1915, Rous and Kidd (3, 4) reported that tar enhanced the carcinogenic activity of the Shope papillomavirus for the rabbit skin. Since then, numerous reports of interaction between viruses and chemical carcinogens have been published (revs. 5–15) with the majority of these showing synergism. These findings have attracted increasing attention as evidence is mounting that human populations are often exposed to both viruses and chemical carcinogens and that the high incidence of human cancer in certain geographic areas can be attributed to viral-chemical synergistic action. The focus of this section is to review studies indicative of viral-chemical interaction in tumorigenesis in humans, experimental animals, and cell culture systems.

For the Abbreviations Used see p. 619.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Abbreviations

AFB1 :

aflatoxin B1

ATL:

adult T-cell leukemia

BaP:

benzo[α]pyrene

BL:

Burkitt’s lymphoma

BPV:

bovine papillomavirus

CRPV:

cottontail rabbit papillomavirus

DEN:

diethylnitrosamine

DHBV:

duck hepatitis B virus

DMBA:

7,12-dimethylbenz[α]anthracene

EBV:

Epstein-Barr virus

GSHV:

ground squirrel hepatitis virus

HBV:

hepatitis B virus

HCC:

hepatocellular carcinoma

HHPA:

12-O-hexadecanoyl-16-hydroxyphorbol-13-acetate

HPV:

human papillomavirus

HTLV:

human T-cell leukemia virus

3-MC:

3-methylcholanthrene

MuLV:

murine leukemia virus

NPC:

nasopharyngeal carcinoma

SFV:

Shope fibromavirus

SPV:

Shope papillomavirus,virus

TPA:

12-O-tetradecanoylphorbol-13-acetateV

V:

vaccinia virus

WHV:

woodchuck hepatitis virus

References

  1. Rous, R.: JAMA 56, 198 (1911).

    Google Scholar 

  2. Yamagiwa, K., and Ichikawa, K.: Mitt. Med. Fakult. Kais. Jpn. 15, 295 (1915).

    Google Scholar 

  3. Rous, P., and Kidd, J. G.: Science 83, 468 (1936).

    Article  PubMed  CAS  Google Scholar 

  4. Rous, P., and Kidd, J. G.: J. Exp. Med. 67, 399 (1938).

    Article  PubMed  CAS  Google Scholar 

  5. Duran-Reynals, F.: Texas Repts. Biol. Med. 15, 306 (1957).

    Google Scholar 

  6. Duran-Reynals, M. L.: Prog. Exp. Tumor Res. 3, 148 (1963).

    PubMed  CAS  Google Scholar 

  7. Duran-Reynals, M. L.: Acta Unio Intern. Contra Cancrum 19, 792 (1963).

    CAS  Google Scholar 

  8. Tennant, R. W., and Rascati, R. J.: Mechanisms of Cocarcinogenesis Involving Endogenous Retroviruses. In “Modifiers of Chemical Carcinogenesis” (T. J. Slaga, ed.). Raven Press, New York, 1980, p. 185.

    Google Scholar 

  9. Southam, C. M., Tanaka, S., Arata, T., Simkovic, D., Miura, M., and Petropulos, S. F.: Prog. Exp. Tumor Res. 11, 194(1969).

    PubMed  CAS  Google Scholar 

  10. Yamamoto, N.: Rev. Physiol. Biochem. Pharmacol. 101, 111 (1984).

    Article  PubMed  CAS  Google Scholar 

  11. Harris, C. C., and Sun, T.-T.: Cancer Surveys 5, 765 (1986).

    PubMed  CAS  Google Scholar 

  12. Henderson, E. E.: J. Natl. Cancer Inst. 80, 476 (1988).

    Article  PubMed  CAS  Google Scholar 

  13. Weinstein, I. B.: Cancer, Detection Prev. 14, 253 (1989).

    CAS  Google Scholar 

  14. Aboud, M., Rosner, M., Dombrovsky, A., Revazova, T., Feldman, G., Tolpolar, L., Strilitz-Hassan, Y., and Flugel, R. M.: Leukemia Res. 16, 1061 (1992).

    Article  CAS  Google Scholar 

  15. Jackson, M. E., Campo, M. S., and Gaukroger, J. M.: Crit. Rev. Oncogenesis 4, 277 (1993).

    PubMed  CAS  Google Scholar 

  16. Van Rensburg, S. J., Cook-Mozaffari, P., Van Schalkwyk, D. J., Van der Watt, J. J., Vincent, T. J., and Purchase, I. F.: Br. J. Cancer 51, 713 (1985).

    Article  PubMed  Google Scholar 

  17. Peers, F., Bosch, X., Kaldor, J., Linsell, A., and Pluijmen, M.: Int. J. Cancer 39, 545 (1987).

    Article  PubMed  CAS  Google Scholar 

  18. Yeh, F. S., Yu, M. C., Mo, C. C., Luo, S., Tong, M. J., and Henderson, B. E.: Cancer Res 49, 2506 (1989).

    PubMed  CAS  Google Scholar 

  19. Ross, R. K., Yuan, M. J., Yu, M. C., Wogan, G. N., Qian, G. S., Tu, J. T., Groopman, J. D., Gao, Y. T., and Henderson, B. E.: Lancet 339, 943 (1992).

    Article  PubMed  CAS  Google Scholar 

  20. Qian, G. S., Ross, R. K., Yu, M. C., Yuan, J. M., Gao, Y. T., Henderson, B. E., Wogan, G. N., and Groopman, J. D.: Cancer Epidemiol. Biomarkers Prev. 3, 3 (1994).

    PubMed  CAS  Google Scholar 

  21. Osato, T., Imai, S., Kinoshita, T., Aya, T., Sugiura, M., Koizumi, S., and Mizuno, F.: Epstein-Barr Virus, Burkitt’ Lymphoma, and an African Tumor Promoter. In “Immunobiology and Prophylaxis of Human Herpesvirus Infections” (C. Lopez, ed.). Plenum Press, New York, 1990, p. 147.

    Google Scholar 

  22. Ito, Y., Tokuka, H., Ohigashi, H., and Koshimizu, K.: Distribution and Characterization of Environmental Promoter Substances as Assayed by Synergistic Epstein-Barr Virus-Activating System. In “Cellular Interactions by Environmental Tumor Promoters” (H. Fujiki, ed.). Japan Sci. Soc. Press, Tokyo, 1984, p. 125.

    Google Scholar 

  23. Ho, J. H. C., Huang, D. P., and Fong, Y. Y.: Lancet ii, 626 (1978).

    Article  Google Scholar 

  24. Chang, K. W., Chang, C. S., Lai, K. S., Chou, M. J., and Choo, K. B.: J. Med. Virol. 28, 57 (1989).

    Article  PubMed  CAS  Google Scholar 

  25. Ito, Y., Matsuda, S., Tokuda, H., and Nakao, Y.: Tumor Promoting Diterpene Esters as Possible Environmental Co-factors of ATL. In “Human T-Cell Leukemia/Lymphoma Virus and Adult T-Cell Leukemia” (R. C. Gallo, M. Essex, and L. Gross, eds.). Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York, 1984, p. 69.

    Google Scholar 

  26. Lutwick, I. L.: Lancet i, 755 (1979).

    Article  Google Scholar 

  27. Munoz, N. M., and Bosch, F. X.: Epidemiology of Hepatocellular Carcinoma. In “Neoplasms of the Liver” (K. Okuda and K. G. Ishak, eds.). Springer-Verlag, Tokyo, 1987, p. 3.

    Google Scholar 

  28. Woo, Y.-t., Lai, D. Y., Arcos, J. C., and Argus, M. F.: “Chemical Induction of Cancer-Structural Bases and Biological Mechanisms,” Vol. IIIC: Natural, Metal, Fiber and Macromolecular Carcinogens. Academic Press, San Diego, 1988.

    Google Scholar 

  29. Beasley, R. P.: Cancer 61, 1942 (1988).

    Article  PubMed  CAS  Google Scholar 

  30. Greenblatt, M. S., Bennett, W. P., Hollstein, M., and Harris, C. C.: Cancer Res. 54, 4855 (1994).

    PubMed  CAS  Google Scholar 

  31. Kim, C. M., Koike, K., Saito, I., Miyamura, T., and Jay, G.: Nature 351, 317 (1991).

    Article  PubMed  CAS  Google Scholar 

  32. Wild, C., Jansen, L. A. M., Cova, L., and Montesano, R.: Environ. Health Perspect. 99, 115 (1993).

    Article  PubMed  CAS  Google Scholar 

  33. The Gambia Hepatitis Study Group: Lancet i, 1057 (1989).

    Article  Google Scholar 

  34. de Thé, G., Geser, A., and Day, N. E.: Nature 274, 756 (1978).

    Article  Google Scholar 

  35. Shank, R. C.: Epidemiology of Aflatoxin Carcinogenesis. In “Environmental Cancer” (H. F. Kraybill and M. A. Mehlman, eds.). Wiley, New York, 1977, p. 301.

    Google Scholar 

  36. Henle, W., Henle, G., and Ho, H. C.: J. Natl. Cancer Inst. 44, 225 (1970).

    PubMed  CAS  Google Scholar 

  37. Winkelstein, W.: Am. J. Epidemiol. 131, 945 (1990).

    PubMed  Google Scholar 

  38. Holly, E. A., Whittemore, A. S., Aston, D. A., Ahn, D. K., Nickoloff, B. J., and Kristiansen, J. L.: J. Natl. Cancer Inst. 81, 1726 (1989).

    Article  PubMed  CAS  Google Scholar 

  39. Cann, A. J., and Chen, I. S. Y.: Human T-Cell Leukemia Virus Types I and II. In “Virology” (B. N. Fields and D. M. Knipe, eds.), 2nd ed. Raven Press, New York, 1990, p. 1501.

    Google Scholar 

  40. Dragani, T. A., Manenti, G., Farza, H., Delia Porta, G., Tiollais, P., and Pourcel, C.: Carcinogenesis 11, 953 (1989).

    Article  Google Scholar 

  41. Sell, S., Hunt, J. M., Dunsford, H. A., and Chisari, F. V.: Cancer Res. 51, 1278 (1991).

    PubMed  CAS  Google Scholar 

  42. Rous, P., and Friedewald, W. F.: J. Exp. Med. 79, 511 (1944).

    Article  PubMed  CAS  Google Scholar 

  43. Rogers, S., and Rous, P.: J. Exp. Med. 93, 459 (1951).

    Article  PubMed  CAS  Google Scholar 

  44. Jarrett, W. F. H.: Bull. Cancer 65, 191 (1978).

    PubMed  CAS  Google Scholar 

  45. Campo, M. S., Moar, M. H., Jarrett, W. F. H., and Laird, H. M.: Nature 286, 180 (1980).

    Article  CAS  Google Scholar 

  46. Campo, M. S.: Cancer Surveys 6, 39 (1987).

    PubMed  CAS  Google Scholar 

  47. Rowson, K. E. K., Roe, F. J. C., Ball, J. K., and Salaman, M. H.: Nature 191, 893 (1961).

    Article  PubMed  CAS  Google Scholar 

  48. Roe, F. J. C., and Rowson, K. E. K.: Int. Rev. Exp. Pathol. 6, 181 (1968).

    PubMed  CAS  Google Scholar 

  49. Ahlström, C. G., and Andrewes, C. N.: J. Pathol. Bacteriol. 47, 65 (1938).

    Article  Google Scholar 

  50. Carr, J. G.: Br. J. Exp. Pathol. 23, 221 (1942).

    CAS  Google Scholar 

  51. Irons, R. D.: Environ. Health Perspect. 86, 49 (1990).

    Article  PubMed  CAS  Google Scholar 

  52. Tanaka, S., and Southam, C. M.: J. Natl. Cancer Inst. 34, 441 (1965).

    PubMed  CAS  Google Scholar 

  53. Imagawa, D. T., Yorhimori, M., and Adams, J. M.: Proc. Am. Assoc. Cancer Res. 2, 217 (1957).

    Google Scholar 

  54. Kotin, P., and Wiseley, D. V.: Prog. Exp. Tumor Res. 3, 186 (1963).

    PubMed  CAS  Google Scholar 

  55. Harris, R. J., and Negroni, C.: Br. Med. J. 58, 6337 (1967).

    Google Scholar 

  56. Schmidt-Ruppin, K. H., and Papadopulu, G.: Z. Krebsforsch. 77, 150 (1972).

    Article  CAS  Google Scholar 

  57. Sherker, A. H., and Marion, P.: Annu. Rev. Microbiol. 45, 475 (1991).

    Article  PubMed  CAS  Google Scholar 

  58. Rogler, C. E.: Curr. Top. Microbiol. Immunobiol. 168, 104 (1991).

    Google Scholar 

  59. Cova, L., Duflot, A., Prave, M., and Trepo, C.: Arch. Virol. [Suppl.] 8, 81 (1993).

    CAS  Google Scholar 

  60. Shope, R. E., and Hurst, E. W.: J. Exp. Med. 58, 607 (1933).

    Article  PubMed  CAS  Google Scholar 

  61. Lancaster, W. D., and Olson, C.: Microbiol. Rev. 46, 191 (1982).

    PubMed  CAS  Google Scholar 

  62. Syverton, J. T.: Ann. NY Acad. Sci. 54, 1126 (1952).

    Article  PubMed  CAS  Google Scholar 

  63. Shope, R. E.: J. Exp. Med. 56, 803 (1932).

    Article  PubMed  CAS  Google Scholar 

  64. Andrewes, C., Allison, A. C., Armstrong, J. A., Bearcroft, G., Niven, J. S. F., and Pereira, H. S.: Acta Unio Int. Contra Cancrum 15, 760 (1959).

    PubMed  CAS  Google Scholar 

  65. Bearcroft, W. G. C., and Jamieson, M. F.: Nature 182, 195 (1958).

    Article  PubMed  CAS  Google Scholar 

  66. LaPlaca, M., Portolani, M., Mannini-Palenzona, A., Barbanti-Brodano, G., and Bernardini, A.: J. Microbiol. 15, 205 (1967).

    Google Scholar 

  67. Vreeswijk, J., Leene, W., and Kalsbeek, G. L.: J. Invest. Dermatol. 69, 249 (1977).

    Article  PubMed  CAS  Google Scholar 

  68. Pound, A. W., and Withers, H. R.: Br. J. Cancer 17, 460 (1963).

    Article  PubMed  CAS  Google Scholar 

  69. Rous, P., and Kidd, J. G.: J. Exp. Med. 73, 365 (1941).

    Article  PubMed  CAS  Google Scholar 

  70. Deelman, H. T.: Z. Krebsforsch. 18, 261 (1923).

    Google Scholar 

  71. Pullinger, B. D.: J. Pathol. Bacteriol. 57, 477 (1945).

    Article  PubMed  CAS  Google Scholar 

  72. Salaman, M. H., and Glendenning, O. M.: Br. J. Cancer 11, 434 (1957).

    Article  PubMed  CAS  Google Scholar 

  73. Mazurenko, N. P.: Probl. Oncol. (USSR). (English Transl.) 6, 873 (1960).

    Google Scholar 

  74. Sula, J.: Neoplasma 26, 1 (1979).

    Google Scholar 

  75. Askanazy, M.: Zentrabl. allg. Pathol, pathol. Anat. 30, 443 (1919).

    Google Scholar 

  76. Tsang, S. S., and Stich, H. F.: Cancer Lett. 43, 93 (1988).

    Article  PubMed  CAS  Google Scholar 

  77. Pennie, W. D., and Campo, M. S.: Virology 190, 861 (1992).

    Article  PubMed  CAS  Google Scholar 

  78. Mitrani-Rosenbaum, S., and Tsvieli, R.: Intervirology 33, 76 (1992).

    PubMed  CAS  Google Scholar 

  79. Garrett, L. R., Perez-Reyes, N., Smith, P. P., and McDougall, J. K.: Carcinogenesis 14, 329 (1993).

    Article  PubMed  CAS  Google Scholar 

  80. Self, R.: J. Virol. 36, 421 (1980).

    Google Scholar 

  81. Diamond, L., Knorr, R., and Shimizu, Y.: Cancer Res. 34, 2599 (1974).

    PubMed  CAS  Google Scholar 

  82. Reznikoff, C. A., Loretz, L. J., Christian, B. J., Wu, S.-Q., and Meisner, L. F.: Carcinogenesis 9, 1427 (1988).

    Article  PubMed  CAS  Google Scholar 

  83. Martin, R. G., Stelow, V. P., and Edwards, C. A. F.: Virol. 31, 596 (1979).

    CAS  Google Scholar 

  84. Tomei, L. D., Noyes, I., Blocker, D., Holliday, J., and Glaser, R.: Nature 329, 73 (1987).

    Article  PubMed  CAS  Google Scholar 

  85. Yamamoto, N., and zur Hausen, H.: Nature 280, 244 (1979).

    Article  PubMed  CAS  Google Scholar 

  86. Casto, B. C.: Cancer Res. 33, 402 (1973).

    PubMed  CAS  Google Scholar 

  87. Casto, B. C., Pieczynski, W. J., and DiPaolo, J. A.: Cancer Res. 34, 72 (1974).

    PubMed  CAS  Google Scholar 

  88. Casto, B. C., Meyer, J., and DiPaolo, J. A.: Cancer Res. 39, 193 (1979).

    PubMed  CAS  Google Scholar 

  89. Fisher, P. B., Weinstein, I. B., Eisenberg, D., and Ginsberg, H.: Proc. Natl. Acad. Sci. U.S.A. 75, 2311 (1978).

    Article  PubMed  CAS  Google Scholar 

  90. Fisher, P. B., Mufson, R. A., Weinstein, I. B., and Little, J. B.: Carcinogenesis 2, 183 (1981).

    Article  PubMed  CAS  Google Scholar 

  91. Freeman, A. E., Price, P. J., Igel, H. J., Young, J. C., Maryak, J. M., and Huebner, R. J.: J. Natl. Cancer Inst. 44, 65 (1970).

    PubMed  CAS  Google Scholar 

  92. Lipp, M., Scherer, B., Lips, G., Brandner, G., and Hunsmann, G.: Carcinogenesis 3, 261 (1982).

    Article  PubMed  CAS  Google Scholar 

  93. Rhim, J. S., Vass, W., Cho, H. Y., and Huebner, R. J.: Int. J. Cancer 7, 65 (1971).

    Article  PubMed  CAS  Google Scholar 

  94. Howard, D. K., Schlom, J. H., and Fisher, P. B.: In Vitro 19, 58 (1983).

    Article  PubMed  CAS  Google Scholar 

  95. Matsuda, S., Nakao, Y., Ohigashi, H., Koshimizu, K., and Ito, Y.: Int. J. Cancer 38, 859 (1986).

    Article  PubMed  CAS  Google Scholar 

  96. Frolov, A. F., Sherbinskaya, A. M., and Botsman, N. E.: Folia Biol. 17, 521 (1971).

    Google Scholar 

  97. zur Hausen, H., Yamamoto, N., and Bauer, G.: Virus Induction by Tumor Promoters. In “Carcinogenesis”, Vol. 7 (E. Hecker, ed.). Raven Press, New York, 1982, p. 617.

    Google Scholar 

  98. Yamamoto, N.: Rev. Physiol. Biochem. Pharmacol. 101, 111 (1984).

    Article  PubMed  CAS  Google Scholar 

  99. Hashida, T., and Yamamoto, S.: J. Gen. Virol. 72, 1569 (1991).

    Article  PubMed  CAS  Google Scholar 

  100. Ishidate, M.: “Data Book on Chromosome Aberration Tests in vitro”. Elsevier, Amsterdam, 1988.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Tulane University School of Medicine, New Orleans, LA, 70112, USA

    Yin-tak Woo

Authors
  1. Yin-tak Woo
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. U.S. Environmental Protection Agency, Washington, D.C., 20460, USA

    Joseph C. Arcos , Mary F. Argus  & Yin-tak Woo ,  & 

  2. Tulane University School of Medicine, New Orleans, LA, 70112, USA

    Joseph C. Arcos  & Mary F. Argus  & 

Rights and permissions

Reprints and permissions

Copyright information

© 1995 Birkhäuser Boston

About this chapter

Cite this chapter

Woo, Yt. (1995). Viral-Chemical Combination Effects in Tumorigenesis. In: Arcos, J.C., Argus, M.F., Woo, Yt. (eds) Chemical Induction of Cancer. Birkhäuser Boston. https://doi.org/10.1007/978-1-4612-4076-1_31

Download citation

  • DOI: https://doi.org/10.1007/978-1-4612-4076-1_31

  • Publisher Name: Birkhäuser Boston

  • Print ISBN: 978-1-4612-8640-0

  • Online ISBN: 978-1-4612-4076-1

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation