Activity, Chemoaffinity and Competition: Factors in the Formation of the Retinotectal Map
For more than forty years, the retinotectal system of lower vertebrates has been used by developmental neurobiologists as a model to study how growing nerve fibers establish ordered neuronal connections in the central nervous system. For the most part, ordered connections has meant the retinotopic order of the optic projection onto contralateral tectum. Much of the early work has been premised on the assumption that the explanation would come down to a single basic principle, the simpler the hypothesis and the more it could explain, the better.
KeywordsMigration Retina Neurol NMDA Choline
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