Tolerance of Perfluorocarbons, Fluorosilicone, and Silicone Liquids in the Vitreous

  • Mark E. Hammer
  • Deborah F. Rinder
  • E. Lynn Hicks
  • Chang-Hsu Yang
  • Carlton A. Hornung

Abstract

Silicone oil (polydimethylsiloxane) has been under investigation for over 20 years as a retinal tamponade in the treatment of retinal detachments. The use of intraocular air and sulfur hexafluoride gas has become routine for the tamponade of retinal breaks after vitrectomy while chorioretinal scarring from cryopexy, diathermy, or photothermal treatment gains adequate mechanical strength. Improvement in the rate of success for retinal reattachment has been reported in cases in which the longer lasting perfluorocarbon gases are used.1 The impression that longer retinal tamponade gives a higher reattachment rate for complex retinal detachments has lead to renewed interest in silicone oil. Clinical studies with silicone oil emphasize either favorable results2–4 or complications.5 Interpretation of the histopathology in these eyes has also varied. Some studies have shown that silicone oil is not toxic,6 while others reported retinal toxicity7 and degeneration of ganglion cells.8

Keywords

Foam Retina Fluor Cataract Butane 

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Copyright information

© Springer-Verlag New York Inc. 1988

Authors and Affiliations

  • Mark E. Hammer
  • Deborah F. Rinder
  • E. Lynn Hicks
  • Chang-Hsu Yang
  • Carlton A. Hornung

There are no affiliations available

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