Clostridial Myconecrosis (Gas Gangrene)

  • W. Lance George
  • Sydney M. Finegold


Certain species of Clostridium, sometimes termed the histotoxic clostridia, produce a necrotizing infection termed gas gangrene or clostridial myonecrosis (MacLennan, 1962). This disease has the potential to be rapidly lethal; prompt diagnosis and treatment can be lifesaving.


Ischemia Penicillin Bacillus Chloramphenicol Metronidazole 


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Literature Cited

  1. Altemeier, W. A., and W. D. Fullen. 1971. Prevention and treatment of gas gangrene. J. Am. Med. Assoc. 217:806.CrossRefGoogle Scholar
  2. Caplan, E. S., and R. M. Kluge. 1976. Gas gangrene: review of 34 cases. Arch. Intern. Med. 136:788.PubMedCrossRefGoogle Scholar
  3. Finegold, S. M. 1977. Anaerobic bacteria in human disease. Academic Press, Inc., New York.Google Scholar
  4. Finegold, S. M., W. L. George, and M. E. Mulligan. 1986. Anaerobic infections. Year Book Medical Publishers, Inc., Chicago.Google Scholar
  5. MacLennan, J. D. 1962. The histotoxic clostridial infections of man. Bacteriol. Rev. 26:177.PubMedGoogle Scholar
  6. Sneath, P. H. A., N. S. Mair, M. E. Sharpe, and J. G. Holt (ed.). 1986. Bergey’s manual of systematic bacteriology, 9th ed., vol. 2. The Williams & Wilkins Co., Baltimore.Google Scholar
  7. Swartz, M. N. 1985. Myositis, p. 613. In G. L. Mandell, R. G. Douglas, Jr., and J. E. Bennett (ed.), Principles and practice of infectious diseases, 2nd ed. John Wiley & Sons, Inc., New York.Google Scholar

Copyright information

© Springer-Verlag New York Inc. 1988

Authors and Affiliations

  • W. Lance George
  • Sydney M. Finegold

There are no affiliations available

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