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Trichomoniasis

  • Henry M. Mathews

Abstract

Trichomoniasis is an infection of the genitourinary tract caused by the flagellated protozoan Trichomonas vaginalis. Infection in women may be asymptomatic or characterized by vaginal itching and discomfort with or without an accompanying discharge (Fouts and Kraus, 1980). In men, infections are most often transient and asymptomatic, but occasionally persistent infection with prostatitis, urethritis, or epididymitis may occur (Krieger, 1981). The disease derives its public health significance from its worldwide distribution, the economic burden for treatment, and the social and psychological impact on patients with persistent infections.

Keywords

Acridine Orange Acridine Orange Vaginal Discharge Indirect Fluorescent Antibody Test Vaginal Secretion 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Literature Cited

  1. Ackers, J. P., W. H. R. Lumsden, R. D. Catterall, and R. Coyle. 1975. Antitrichomonal antibody in the vaginal secretions of women infected with T. vaginalis. Br. J. Vener. Dis. 51:319–323.PubMedGoogle Scholar
  2. Ackers, J. P., R. D. Cattarall, W. H. R. Lumsden, and A. McMillan. 1978. Absence of detectable local antibody in genitourinary tract secretions of male contacts of women infected with Trichomonas vaginalis. Br. J. Vener. Dis. 54:168–171.PubMedGoogle Scholar
  3. Alderete, J. F. 1983. Antigen analysis of several pathogenic strains of Trichomonas vaginalis. Infec. Immun. 39:1041–1047.Google Scholar
  4. Alderete, J. F. 1984. Enzyme-linked immunosorbent assay for detecting antibody to Trichomonas vaginalis: use of whole cells and aqueous extract as antigen. Br. J. Vener. Dis. 60:164–170.PubMedGoogle Scholar
  5. Alderete, J. F., and E. Pearlman. 1984. Pathogenic Trichomonas vaginalis cytotoxicity to cell culture monolayers. Br. J. Vener. Dis. 60:99–105.PubMedGoogle Scholar
  6. Bennett, B. D., J. Bailey and W. A. Gardner, Jr. 1980. Immunocytochemical identification of trichomonads. Arch. Pathol. Lab. Med. 104:247–249.PubMedGoogle Scholar
  7. Bromke, B.J. 1986. A serum-free, lipid-supplemented medium for the growth of Trichomonas vaginalis. J. Microbiol. Methods 6:55–59.CrossRefGoogle Scholar
  8. Chang, T. H., S. Y. Tsing, and S. Tzeng. 1986. Monoclonal antibodies against Trichomonas vaginalis. Hybridoma 5:43–51.PubMedCrossRefGoogle Scholar
  9. Cogne, M., P. Brasseur, and J. J. Ballet. 1985. Detection and characterization of serum antitrichomonal antibodies in urogenital trichomoniasis. J. Clin. Microbiol. 21:588–592.PubMedGoogle Scholar
  10. Diamond, L. S. 1957. The establishment of various trichomonads of animals and man in axenic cultures. J. Parasitol. 43:488–490.PubMedCrossRefGoogle Scholar
  11. Feinberg, J. G., and M. J. Whittington. 1957. A culture medium for Trichomonas vaginalis Donne and species of Candida. J. Clin. Pathol. 10:327–329.PubMedCrossRefGoogle Scholar
  12. Fouts, A. C., and S. J. Kraus. 1980. Trichomonas vaginalis: reevaluation of its clinical presentation and laboratory diagnosis. J. Infect. Dis. 141:137–143.PubMedCrossRefGoogle Scholar
  13. Fripp, P. J., P. R. Mason, and H. Super. 1975. A method for the diagnosis of Trichomonas vaginalis using acridine orange. J. Parasitol. 61:966–967.PubMedCrossRefGoogle Scholar
  14. Gardner, W. A., Jr., D. E. Culberson, and B. D. Bennett. 1986. Trichomonas vaginalis in the prostate gland. Arch. Pathol. Lab. Med. 110:430–432.PubMedGoogle Scholar
  15. Gradus, M. S., and H. M. Matthews. 1985. Electrophoretic analysis of soluble proteins and esterase, superoxide dismutase and acid phosphotase isoenzymes of members of the protozoan family Trichomonadidae. Comp. Biochem. Physiol. 81B:229–233.Google Scholar
  16. Honigberg, B. M. 1961. Comparative pathogenicity of Trichomonas vaginalis and Trichomonas gallinae to mice. I. Gross pathology, quantitative evaluation of virulence, and some factors affecting pathogenicity. J. Parasitol. 47:545–571.PubMedCrossRefGoogle Scholar
  17. Honigberg, B. M. 1970. Trichomonads. In G. J. Jackson, R. Herman, and L. Singer (ed.), Immunity to parasitic animals, Vol. 2. Appleton, New York.Google Scholar
  18. Honigberg, B. M. 1978. Trichomonads of importance in human medicine, p. 275–454. In J. P. Kreier (ed.), Parasitic protozoa, Vol. 2. Academic Press, New York.Google Scholar
  19. Honigberg, B. M., P. K. Gupta, M. R. Spence, J. K. Frost, K. Kuczynska, L. Choromanski, and A. Warton, 1984. Pathogenicity of Trichomonas vaginalis: cytopathologic and histopathologic changes of the cervical epithelium. Obstet. Gynecol. 64:179–184.PubMedGoogle Scholar
  20. Hume, J. C. 1978. Trichomoniasis—eight reasons why you should take it seriously. Med. Times 106:59–63.PubMedGoogle Scholar
  21. Jirovec, O., and M. Petru. 1968. Trichomonas vaginalis and trichomoniasis. Adv. Parasitol. 6:117–188.PubMedCrossRefGoogle Scholar
  22. Jones, J. G., T. Yamauchi, and B. Lambert. 1985. Trichomonas vaginalis infestation in sexually abused girls. Am. J. Dis. Child. 139:846–847.PubMedGoogle Scholar
  23. Krajden, S., J. G. Lossick, E. Wilk, J. Yang, J. S. Keystone, and K. Elliot. 1986. Persistent Trichomonas vaginalis infection due to a metronidazole-resistant strain. Can. Med. Assoc. J. 134:1373–1374.Google Scholar
  24. Krieger, J. N. 1981. Urologic aspects of trichomoniasis. Invest. Urol. 18:411–417.PubMedGoogle Scholar
  25. Krieger, J. N., M. A. Poisson, and M. F. Rein. 1983. Betahemolytic activity of Trichomonas vaginalis correlates with virulence. Infect. Immun. 41:1291–1295.PubMedGoogle Scholar
  26. Krieger, J. N., K. K. Holmes, M. R. Spence, M. F. Rein, W. M. McCormack, and W. R. Tam. 1985a. Geographic variation among isolates of Trichomonas vaginalis: demonstration of antigenic heterogeneity by using monoclonal antibodies and the indirect immunofluorescence technique. J. Infect. Dis. 152:979–984.PubMedCrossRefGoogle Scholar
  27. Krieger, J. N., J. I. Ravdin, and M. F. Rein. 1985b. Contact-dependent cytopathogenic mechanisms of Trichomonas vaginalis. Infect. Immun. 50:778–786.PubMedGoogle Scholar
  28. Kuberski, T. 1978. Evaluation of the indirect hemagglutination technique for study of Trichomonas vaginalis infections, particularly in men. Sex. Transm. Dis. 5:97–102.PubMedCrossRefGoogle Scholar
  29. Levett, P. N. 1980. A comparison of five methods for the detection of Trichomonas vaginalis in clinical specimens. Med. Lab. Sci. 37:85–88.PubMedGoogle Scholar
  30. Linstead, D. 1981. New defined and semi-defined media for the cultivation of the flagellate Trichomonas vaginalis. Parasitology 83:125–137.PubMedCrossRefGoogle Scholar
  31. Littlewood, J. M., and H. G. Kohler. 1966. Urinary tract infection by Trichomonas vaginalis in a newborn baby. Arch. Dis. Child. 41:693–695.PubMedCrossRefGoogle Scholar
  32. Lossick, J. G. 1982. Treatment of Trichomonas vaginalis infections. Rev. Infect. Dis. (Suppl.) 4:S801–S818.Google Scholar
  33. Lossick, J. G., M. Muller, and T. E. Gorrell. 1986. In vitro drug susceptibility and doses of metronidazole required for cure in cases of refractory vaginal trichomoniasis. J. Infect. Dis. 153:948–955.PubMedCrossRefGoogle Scholar
  34. Mason, P. R. 1979. Serodiagnosis of Trichomonas vaginalis infection by the indirect fluorescent antibody test. J. Clin. Pathol. 32:1211–1215.PubMedCrossRefGoogle Scholar
  35. Mason, P. R., H. Super, and P. J. Fripp. 1976. Comparison of four techniques for the routine diagnosis of Trichomonas vaginalis infection. J. Clin. Pathol. 29:154–157.PubMedCrossRefGoogle Scholar
  36. Mathews, H. M., and G. R. Healy. 1983. Evaluation of two serologic tests for Trichomonas vaginalis infection. J. Clin. Microbiol. 17:840–843.PubMedGoogle Scholar
  37. McLaren, L. C., L. E. Davis, G. R. Healy, and C. G. James. 1983. Isolation of Trichomonas vaginalis from the respiratory tract of infants with respiratory disease. Pediatrics 71:888–890.PubMedGoogle Scholar
  38. McLellan, R., M. R. Spence, M. Brockman, L. Raffel, and J. L. Smith. 1982. The clinical diagnosis of trichomoniasis. Obstet. Gynecol. 60:30–34.PubMedGoogle Scholar
  39. Muller, M. 1980. The hydrogenosome. In G. W. Gooday, D. Lloyd, and A. P. J. Trinci (ed.), The eukaryotic microbial cell. Cambridge University Press, Cambridge, U.K.Google Scholar
  40. Muller, M., J. G. Meingasser, W. A. Miller, and W. J. Ledger. 1980. Three metronidazole-resistant strains of Trichomonas vaginalis from the United States. Am. J. Obstet. Gynecol. 138:808–812.PubMedGoogle Scholar
  41. Neinstein, L. S., J. Goldenring, and S. Carpenter. 1984. Nonsexual transmission of sexually transmitted diseases: an infrequent occurrence. Pediatrics 74:67–76.PubMedGoogle Scholar
  42. O’Hara, C. M., W. A. Gardener, Jr., and B. D. Bennett. 1980. Immunoperoxidase staining of Trichomonas vaginalis in cytologic material. Acta Cytol. 24:448–451.PubMedGoogle Scholar
  43. Perl, G. 1972. Errors in the diagnosis of Trichomonas vaginalis infection as observed among 1199 patients. Obstet. Gynecol. 39:7–9.PubMedGoogle Scholar
  44. Philip, A., P. Carter-Scott, and C. Rogers. 1987. An agar culture technique to quantitate Trichomonas vaginalis from women. J. Infect. Dis. 155:304–308.PubMedCrossRefGoogle Scholar
  45. Rebhun, J. 1964. Pulmonary trichomoniasis associated with a fever of unknown origin. Calif. Med. 100:443–444.PubMedGoogle Scholar
  46. Smith, R. F. 1983. Viability of Trichomonas vaginalis in vitro at four temperatures. J. Clin. Microbiol. 18:834–836.PubMedGoogle Scholar
  47. Smith, R. F. 1986. Incubation time, second blind passage, and cost considerations in the isolation of Trichomonas vaginalis. J. Clin. Microbiol. 24:139–140.PubMedGoogle Scholar
  48. Smith, R. F., R. Welch, R. Stickney, S. Venerable, S. Fredrickson, K. Shima, and P. Hilton. 1982. Serum-free modified Trichosel medium for the isolation of Trichomonas vaginalis. Curr. Microbiol. 7:153–156.CrossRefGoogle Scholar
  49. Soliman, M. A., J. P. Ackers, and R. D. Catterall. 1982. Isoenzyme characterisation of Trichomonas vaginalis. Br. J. Vener. Dis. 58:250–256.PubMedGoogle Scholar
  50. Street, D. A., D. Taylor-Robinson, J. P. Ackers, N. F. Hanna, and A. McMillan. 1982. Evaluation of an enzyme-linked immunosorbent assay for the detection of antibody to Trichomonas vaginalis in sera and vaginal secretions. Br. J. Vener. Dis. 58:330–333.PubMedGoogle Scholar
  51. Su, K. E. 1982. Antibody to Trichomonas vaginalis in human cervicovaginal secretions. Infect. Immun. 37:852–857.PubMedGoogle Scholar
  52. Su-Lin, K. E., and B. M. Honigberg. 1983. Antigenic analysis of Trichomonas vaginalis strains by quantitative fluorescent antibody methods. Z. Parasitenkd. 69:161–181.PubMedCrossRefGoogle Scholar
  53. Torian, B. E., R. J. Connelly, R. S. Stephens, and H. H. Stibbs. 1984. Specific and common antigens of Trichomonas vaginalis detected by monoclonal antibodies. Infect. Immun. 43:270–275.PubMedGoogle Scholar
  54. Trussell, R. E. 1947. Trichomonas vaginalis and trichomoniasis. Charles C. Thomas, Springfield, IL.Google Scholar
  55. Warton, A., and B. M. Honigberg. 1983. Analysis of surface saccharides in Trichomonas vaginalis strains with various pathogenicity levels by fluorescein-conjugated plant lectins. Z. Parasitenkd. 69:149–159.PubMedCrossRefGoogle Scholar
  56. Watt, R. M., A. Philip, S. M. Wos, and G. J. Sam. 1986. Rapid assay for immunological detection of Trichomonas vaginalis. J. Clin. Microbiol. 24:551–555.PubMedGoogle Scholar

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© Springer-Verlag New York Inc. 1988

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  • Henry M. Mathews

There are no affiliations available

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