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Orthopedic Infection pp 76–91Cite as

Chronic Infective Arthritis

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Part of the book series: Clinical Topics in Infectious Disease ((CLIN.TOP.INFECT))

Abstract

Mycobacteria, fungi, and saprophytic bacteria typically infect bones and joints from remote sites of infection via lymphatic spread, hematogenous spread, or spread along planes of tissue destruction. Occasionally they are introduced directly into the joint by penetrating trauma, surgery, or arthrocentesis. They produce a low-grade synovitis. Relatively early in the course of these chronic infections, symptoms prompting medical attention are local pain, stiffness, mild to moderate swelling, warmth, and erythema over the involved area. The granulomatous reaction associated with these infections can lead to substantial tissue destruction and is characterized by a mononuclear cell and giant cell inflammatory infiltrate, fibroblast proliferation, minimal edema, small vessel congestion, and little fibrin deposition.

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Authors
  1. Maren L. Mahowald
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  2. Ronald P. Messner
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Editors and Affiliations

  1. Temple University School of Medicine, Philadelphia, Pennsylvania, 19125, USA

    David Schlossberg M.D., F.A.C.P. (Professor of Medicine, Director) (Professor of Medicine, Director)

  2. Department of Medicine, Episcopal Hospital, Philadelphia, Pennsylvania, 19125, USA

    David Schlossberg M.D., F.A.C.P. (Professor of Medicine, Director) (Professor of Medicine, Director)

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Mahowald, M.L., Messner, R.P. (1988). Chronic Infective Arthritis. In: Schlossberg, D. (eds) Orthopedic Infection. Clinical Topics in Infectious Disease. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-3870-6_7

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  • DOI: https://doi.org/10.1007/978-1-4612-3870-6_7

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  • Print ISBN: 978-1-4612-8383-6

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