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Mice Immunized to Insulin Develop Anti-idiotypic Antibody to the Insulin Receptor

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Anti-Idiotypes, Receptors, and Molecular Mimicry

Abstract

Several diseases of man can be related to the formation of autoantibodies that interact with surface receptors. Examples are the antibodies that trigger TSH receptor in Graves’ disease (1), antibodies that bind to and block the receptor for acetylcholine at the neuromuscular junction in myasthenia gravis (2), and antibodies that trigger insulin like responses which appear in certain (very rare) types of severe insulin-resistant diabetes (3).

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Authors
  1. Yoram Shechter
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  2. Dana Elias
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  3. Rafael Bruck
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  4. Ruth Maron
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  5. Irun R. Cohen
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Editor information

Editors and Affiliations

  1. Department of Pathology and Laboratory Medicine, University of Texas Health Science Center, TX, 77225, Houston, USA

    D. Scott Linthicum

  2. Department of Medicine, Memorial University, St. Johns, Newfoundland, A1B 3V6, Canada

    Nadir R. Farid

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© 1988 Springer-Verlag New York Inc.

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Shechter, Y., Elias, D., Bruck, R., Maron, R., Cohen, I.R. (1988). Mice Immunized to Insulin Develop Anti-idiotypic Antibody to the Insulin Receptor. In: Linthicum, D.S., Farid, N.R. (eds) Anti-Idiotypes, Receptors, and Molecular Mimicry. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-3734-1_8

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  • DOI: https://doi.org/10.1007/978-1-4612-3734-1_8

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4612-8325-6

  • Online ISBN: 978-1-4612-3734-1

  • eBook Packages: Springer Book Archive

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