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Pinealomas: Need for an Ultrastructural Diagnosis

  • Jacques Hassoun
  • Danielle Gambarelli

Abstract

The pineal region is a highly privileged area of the brain. It includes many cell types of glial or non-glial origin. The pineal body itself contains a wide range of cells, pinealocytes, astrocytes, oligodendrocytes, ependy- mocytes, ganglion cells and even Schwann cells from the conary nerve. Moreover, the high frequency of germinomas, suggests that germ cells are another possible cell type of the human pineal body. This explains why a variety of tumors can develop in this region. The most accurate means of diagnosis, in this area, remains the stereotactic biopsy but the main disadvantage of this method is the small size of the biopsied specimen. It is the reason why electron microscopy appears, even more than immunohistochemistry, to be a useful tool for diagnosis in the frequent cases of small round cell tumor. Pinealomas offer a typical example of such a diagnostic process.

Keywords

Germ Cell Tumor Pineal Gland Stereotactic Biopsy Pineal Region Small Round Cell Tumor 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag New York Inc. 1989

Authors and Affiliations

  • Jacques Hassoun
    • 1
  • Danielle Gambarelli
    • 1
  1. 1.Laboratoire d’Anatomie Pathologique et de NeuropathologieFaculté de Médicine, et l’Hopital de la TimoneMarseilleFrance

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