Clinical Correlations of Malignant Ependymomas
The points of the following presentation are two-fold. The first illustrates the need to separate the embryonal central neuroepithelial tumors from those which are essentially composed of more differentiated, or adult-type cells in which anaplastic change has occurred. This is because those two distinct categories of neoplasm may display different biological, and therefore clinical, behavior. The second point is that, whereas clear clinicohistological correlations have been established in the astrocytomas, no such concordance seems to be apparent in the case of ependymomas that show histologic features of malignancy, provided the ependymoblastomas are excluded from the analysis.
KeywordsAttenuation Adenoma Sarcoma Trypsin Fibril
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