Because of the inherent myocardial motion, hemodynamic variables of the coronary microcirculation have been difficult to examine in the intact, freely beating heart. However, some of these variables, such as pressure and diameter, have previously been examined using a free-motion technique (Nellis et al., 1981). With the use of a low-light-level video camera and fluorescent microscopy, we have developed a technique for using particles as flow tracers, specifically to measure the velocity of flow in vessels of the coronary microcirculation.
KeywordsRespiration Carboxylate Ketamine Xenon Pentobarbital
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