Gastric Carcinoma — Precancerous Conditions and Lesions, Classification, and Prognosis

  • P. Hermanek
Conference paper


As has been done for other organs, the term “precancerosis” with regard to the stomach should be subdivided into two separate categories. A precancerous condition is a clinically defined state which involves an elevated risk of cancer in comparison with the normal population. By contrast, a precancerous lesion is defined as a histopathologic abnormality in which cancer is more likely to occur than its apparently normal counterpart. Epithelial dysplasia is the histological substrate of the precancerous lesion.1


Gastric Carcinoma Precancerous Condition Intestinal Metaplasia Atrophic Gastritis Precancerous Lesion 
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  1. 1.
    Hermanek P: Dysplasia in the gastrointestinal tract: definition and clinical significance. Surg Endosc 1987; 1: 5.PubMedCrossRefGoogle Scholar
  2. 2.
    Heilmann KL: Gastritis-intestinale Metaplasie—Karzinom. Stuttgart, Georg Thieme, 1978.Google Scholar
  3. 3.
    Jass JR: A classification of gastric dysplasia. Histopathology 1983; 7: 181.PubMedCrossRefGoogle Scholar
  4. 4.
    Segura DI, Montero C: Histochemical characterization of different types of intestinal metaplasia in gastric mucosa. Cancer 1983; 52: 498.PubMedCrossRefGoogle Scholar
  5. 5.
    Morson BC, Jass JR, Sobin LH: Precancerous Lesions of the Gastrointestinal Tract. A Histological Classification. London, Bailliere Tindall, 1985, p 5.Google Scholar
  6. 6.
    Oota K, Sobin LH: Histological typing of gastric and oesophageal tumours. International Histological Classification of Tumours. No. 18. Geneva, WHO, 1977, p 38.Google Scholar
  7. 7.
    Hermanek P: Magenkarzinom-Typing, grading, staging, in Gall FP, Hermanek P, Hornig D (eds): Magenkarzinom: Epidemiologie, Pathologie, Therapie, Nachsorge. Munich-Bern-Vienna, W Zuckschwerdt, 1986, p 36.Google Scholar
  8. 8.
    Craven J: Prognostic indices in stomach cancer, in Stoll BA (ed): Pointers to Cancer Prognosis. Dordrecht, Martinus Nijhoff, 1987, p 322.Google Scholar
  9. 9.
    Laurén P: The two histological main types of gastric carcinoma: diffuse and so-called intestinal-type carcinoma. Acta Path Microbiol Scand 1965; 64: 31.PubMedGoogle Scholar
  10. 10.
    Giedl J: Klinische Bedeutung der histologischen Typenbestimmung beim Magenkrebs. Mün Med Wschr 1980; 122: 205.Google Scholar
  11. 11.
    Munoz N, Correa P, Cuello C, et al: Histologic types of gastric carcinoma in high-and low-risk areas. Inter J Cancer 1968; 3: 809.CrossRefGoogle Scholar
  12. 12.
    Husemann B. Altendorf A: Magenkarzinomrezidiv-eine vermeidbare Komplikation? in Jakesz R (ed): Derzeitiger Stand in Diagnose und Therapie des Magenkarzinoms. Vienna, Facultas, 1987, p 134.Google Scholar
  13. 13.
    Husemann B, Altendorf-Hofmann A: Hat der histologische Typ nach Laurén für die Planung des operativen Vorgehens bei kurativer Therapie des Magenkarzinoms Bedeutung? Langenbecks Arch Chir 1987; 372: 867.CrossRefGoogle Scholar
  14. 14.
    Hermanek P, Gall FP: Intestinal and diffuse type of gastric carcinoma. Two clinical entities. J Cancer Res Clin Oncol 1986; 111 (suppl): 82.CrossRefGoogle Scholar
  15. 15.
    Hornig D, Hermanek P, Gall FP: The significance of the extent of proximal margin of clearance in gastric cancer surgery. Scand J Gastroenterol 1987; 22 (suppl 133): 69.CrossRefGoogle Scholar
  16. 16.
    Hermanek P, Sobin LH (eds): UICC: TNM Classification of Malignant Tumours, ed 4. Berlin-Heidelberg-New York, Springer, 1987, p 43.Google Scholar
  17. 17.
    Hermanek P, Scheibe O, Spiessl B, et al (eds): UICC: TNM-Klassifikation maligner Tumoren, ed 4. Berlin-Heidelberg-New York, Springer, 1987, p 45.Google Scholar
  18. 18.
    Guggenmoos-Holzmann I, Hermanek P: Multivariate Analyse der Therapieergebnisse bei kolorektalen Karzinomen, in Hermanek P (ed): Bedeutung des TNM-Systems für die klinische Onkologie. Munich-Bern-Vienna, W. Zuckschwerdt, 1986, p 223.Google Scholar
  19. 19.
    Hermanek P: Klinische Krebsforschung, in Gall FP, Hermanek P, Tonak J (eds): Chirurgische Onkologie, Histologie-und stadien-gerecht Therapie maligner Tumoren. Berlin-Heidelberg-New York, Springer, 1986, p 236.Google Scholar
  20. 20.
    Hermanek P, Guggenmoos-Holzmann I: Multivariate analysis of prognosis following curative tumor resection of stomach carcinoma, abstract from the Proceedings of the 4th European Conference on Clinical Oncology and Cancer Nursing (ECCO), held at Madrid, November 1–4 1987. Madrid, Fundación para la Investigacion y la Formacion en Oncologia, 1987, p 32.Google Scholar

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© Springer-Verlag New York, Inc. 1989

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  • P. Hermanek

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