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Antigen Society #13 Report (B7, B27, Bw47, Bw73): Six Subtypes of HLA-B7 Defined by Histotypes, Epitopes and 1D-IEF

  • G. A. van Seventer
  • A. R. van der Horst
  • J. Semeijn
  • N. M. Lardy
  • F. E. J. M. Krom
  • B. S. Breur-Vriesendorp
  • L. P. de Waal
  • P. Ivanyi

Abstract

The HLA-B7 antigen was one of the best serologically defined HLA antigens in the Ninth Histocompatibility Workshop in 1984. Nevertheless, we could describe at least four different subtypes of the HLA-B7 antigen (*1). We now present data indicating a further heterogeneity of the HLA-B7 antigen as analyzed by HLA-B7 allospecific CTL clones, conventional pregnancy sera, and ID-IEF.

Keywords

Rhabdomyosarcoma Cell Line Human Fibroblast Cell Line Human Rhabdomyosarcoma Cell Human Rhabdomyosarcoma Cell Line Pregnancy Seron 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. 1.
    Van Seventer GA, Huis B, Melief CJM, Ivanyi P. Fine specificity of human HLA-B7-specific cytotoxic T-lymphocyte clones. I. Identification of HLA-B7 subtypes and histotopes of the HLA-B7 cross-reacting group. Hum Immunol 1986; 1375.Google Scholar
  2. 2.
    Reekers P, Van der Beucken M, Andrien M, Beelen J, Mueller-Eckhardt G, Schreuder GMTh. HLA-BPot: A new HLA antigen within the B7-cross-reactive group. Tissue Antigens 1986; 28: 182.PubMedCrossRefGoogle Scholar
  3. 3.
    Taketani S, Krangel MS, Spits H, De Vries JE, Strominger JL. Structural analysis of an HLA-B7 antigen variant detected by cytotoxic T-lymphocytes. J Immunol 1984; 133: 816.PubMedGoogle Scholar

Copyright information

© Springer-Verlag New York 1989

Authors and Affiliations

  • G. A. van Seventer
  • A. R. van der Horst
  • J. Semeijn
  • N. M. Lardy
  • F. E. J. M. Krom
  • B. S. Breur-Vriesendorp
  • L. P. de Waal
  • P. Ivanyi

There are no affiliations available

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