Antigen Society #13 Report (B7, B27, Bw47, Bw73): Six Subtypes of HLA-B7 Defined by Histotypes, Epitopes and 1D-IEF

  • G. A. van Seventer
  • A. R. van der Horst
  • J. Semeijn
  • N. M. Lardy
  • F. E. J. M. Krom
  • B. S. Breur-Vriesendorp
  • L. P. de Waal
  • P. Ivanyi
Conference paper

Abstract

The HLA-B7 antigen was one of the best serologically defined HLA antigens in the Ninth Histocompatibility Workshop in 1984. Nevertheless, we could describe at least four different subtypes of the HLA-B7 antigen (*1). We now present data indicating a further heterogeneity of the HLA-B7 antigen as analyzed by HLA-B7 allospecific CTL clones, conventional pregnancy sera, and ID-IEF.

Keywords

Tyrosine Prefix Rhabdomyosarcoma 

References

  1. 1.
    Van Seventer GA, Huis B, Melief CJM, Ivanyi P. Fine specificity of human HLA-B7-specific cytotoxic T-lymphocyte clones. I. Identification of HLA-B7 subtypes and histotopes of the HLA-B7 cross-reacting group. Hum Immunol 1986; 1375.Google Scholar
  2. 2.
    Reekers P, Van der Beucken M, Andrien M, Beelen J, Mueller-Eckhardt G, Schreuder GMTh. HLA-BPot: A new HLA antigen within the B7-cross-reactive group. Tissue Antigens 1986; 28: 182.PubMedCrossRefGoogle Scholar
  3. 3.
    Taketani S, Krangel MS, Spits H, De Vries JE, Strominger JL. Structural analysis of an HLA-B7 antigen variant detected by cytotoxic T-lymphocytes. J Immunol 1984; 133: 816.PubMedGoogle Scholar

Copyright information

© Springer-Verlag New York 1989

Authors and Affiliations

  • G. A. van Seventer
  • A. R. van der Horst
  • J. Semeijn
  • N. M. Lardy
  • F. E. J. M. Krom
  • B. S. Breur-Vriesendorp
  • L. P. de Waal
  • P. Ivanyi

There are no affiliations available

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