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HLA Class II Typing by the Workshop Defined RFLP Specificities in Unrelated Individuals

  • M. Martell
  • A. Marcadet
  • D. Cohen

Abstract

The Southern blot component of the Tenth International Workshop (WS) was based on the study of 70 cell lines, most of which were homozygous for the HLA complex. Thirty-four different, DR, DQ, Dw haplotypes emerged from serologic and Dw typings. The Tenth Workshop analysis demonstrates conclusively that almost all of these 34 haplotypes can be detected using RFLP techniques. This method, therefore, provides a convenient tool for accurate typing, which can now be based on a standard method. The aim of this chapter is to discuss the practical aspects of DR-DQ RFLP typing.

Keywords

Chronic Myeloid Leukemia Molecular Weight Marker Fragment Pattern Double Intensity RFLP Pattern 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag New York 1989

Authors and Affiliations

  • M. Martell
  • A. Marcadet
  • D. Cohen

There are no affiliations available

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